Hub : Genes

SLC9B1

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 CommonMind Brain Pre-frontal Cortex 0.132 0.0320 0.0000 0.229 0.155 0.242 0.147 0.130 1.8e-27 2.0e-18 4.4e-29 1.6e-17 1.4e-15
2 METSIM Adipose 0.024 0.0138 0.0035 0.026 0.011 0.022 0.009 0.024 7.4e-05 6.3e-03 2.3e-04 1.4e-02 1.2e-04

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2
Bipolar Disorder (2018) 0.4 0.7 0.9 -0.7 -1.0
Bipolar Disorder or Schizophrenia 2.3 5.5 10.4 -3.2 0.7
Depressed Affect (Nagel 2018) 1.8 3.7 5.7 2.4 -1.3
Depression (Nagel 2018) 0.5 0.8 1.0 1.0 -0.8
Intelligence (Savage-Jansen 2018) 0.5 1.4 2.7 -1.6 -0.4
Neuroticism (Nagel 2018) 2.0 4.7 7.6 2.7 -1.4
Schizophrenia (2018) 3.8 7.9 12.8 -3.6 1.7
Schizophrenia vs Biploar Disorder 0.6 0.8 1.6 -0.2 1.2
Worry (Nagel 2018) 0.3 0.5 1.1 1.0 -0.1
Alzheimer’s Disease (in mother) 0.2 0.2 0.4 0.2 0.6
Alzheimer’s Disease (in father) 0.0 0.0 0.1 -0.1 0.3
Alzheimer’s Disease (including proxy) 0.2 0.3 0.4 0.5 0.6
Crohns Disease (2017) 0.9 2.0 3.7 0.6 -1.9
Irritable Bowel Disease (IBD) 1.7 4.1 6.2 -2.5 1.4
Ulcerative Colitis (UC) 7.9 14.8 15.8 -4.0 3.7
Major Depression (MDD) 0.2 0.2 0.3 -0.5 -0.3
Reaction Time 1.1 2.1 2.6 -1.3 1.6
Verbal and Numeric Reasoning (VNR) 0.4 0.9 1.1 -0.8 -1.1
Breast Cancer 0.5 1.1 1.8 -1.4 -0.6
Ovarian Cancer 0.2 0.3 0.3 -0.6 0.5
Prostate Cancer 0.4 0.5 1.1 0.1 1.0
Age at First Birth 0.4 0.6 0.8 0.5 -0.9
Bipolar Disorder (2011) 1.9 1.8 3.6 -0.1 -1.9
Body Mass Index (BMI) (2010) 4.3 5.8 8.0 2.8 -1.9
Coronary Artery Disease (CAD) 0.7 0.8 1.7 0.1 1.3
Crohns Disease (2012) 2.2 3.6 4.4 2.1 -1.6
Mean Putamen Volume 1.2 1.4 2.7 -1.6 0.2
Fasting Glucose 9.9 11.9 15.8 2.8 -4.0
HbA1C 2.0 2.2 2.2 1.5 -1.5
HDL Cholesterol 1.7 2.8 3.3 -1.8 1.5
LDL Cholesterol 0.2 0.3 0.6 -0.1 -0.8
Lupus 1.1 1.7 3.5 -0.1 1.9
Neuroticism (2016) 1.7 2.4 3.6 1.9 -1.1
Primary Biliary Cirrhosis 19.9 28.4 37.7 -4.4 6.1
Rheumatoid Arthritis 1.8 2.5 5.0 -2.2 0.0
Schizophrenia (2014) 3.3 7.3 13.6 -3.7 0.9
Triglycerides 1.5 2.5 2.6 1.6 1.5
Type 2 Diabetes (T2D) (2012) 10.7 12.3 18.7 4.3 -2.4
Ulcerative Colitis 6.6 9.6 10.6 -2.9 3.3
Blood Eosinophil Count 1.5 11.7 22.5 -1.0 4.7
Blood Platelet Count 0.2 2.0 4.0 0.2 -2.0
Blood Red Count 1.3 12.9 22.3 1.9 -4.7
Blood White Count 1.4 10.2 19.3 -1.0 4.4
Heel T-Score 0.6 4.9 9.9 -3.1 -0.2
BMI 1.9 11.1 17.0 4.1 -2.3
Height 0.7 12.6 17.6 -4.2 2.8
Waist Hip Ratio (WHR) 0.7 2.9 5.8 0.2 2.4
Systolic Blood Pressure 0.1 0.5 1.0 1.0 0.0
Smoking Status 0.3 0.8 1.4 -1.2 -0.3
Allergy or Eczema 10.8 28.4 45.4 3.4 -6.7
Cardiovascular Disease 6.9 22.8 34.2 5.9 -3.4
Hypothyroidism (self reported) 0.0 0.0 0.0 -0.0 -0.0
Respiratory disease 4.4 9.7 10.5 3.0 -3.2
Type 2 Diabetes (T2D) (2018) 3.1 5.9 9.9 3.1 -1.4
Lung FEV1/FVC ratio 0.3 1.5 2.4 0.8 -1.6
Lung FVC 0.2 1.0 1.9 -1.4 -0.1
Neuroticism 1.3 3.0 4.0 2.0 -1.4
Chronotype (morning person) 3.8 8.9 14.1 3.8 -1.9
Hair Pigment 0.1 2.8 5.7 2.4 0.0
Tanning 0.0 0.4 0.7 -0.1 0.9
Hand grip strength (left) 0.5 1.3 2.0 -1.4 0.7
Number of treatments/medications taken 13.8 24.9 37.2 6.1 -3.5
Average weekly spirits intake 0.2 0.3 0.5 -0.4 -0.7
Sensitivity / hurt feelings 5.2 8.8 12.9 3.6 -2.2
Frequency of depressed mood in last 2 weeks 1.8 2.6 3.4 1.8 -1.3
Hearing difficulty/problems: Yes 3.6 5.5 9.7 1.1 -3.1
Relative age of first facial hair 1.9 3.9 4.8 -2.2 1.7
Other serious medical condition/disability diagnosed by doctor 1.7 2.2 4.4 -0.2 2.1
Ever used hormone-replacement therapy (HRT) 6.1 7.8 10.6 3.3 -2.2
Ever had hysterectomy (womb removed) 4.2 4.8 7.4 2.7 -1.5
Systolic blood pressure, automated reading 0.1 0.2 0.4 -0.1 -0.7
Eye problems/disorders: Diabetes related eye disease 0.8 0.9 1.2 0.7 -1.1
Angina 0.4 0.5 0.6 0.6 -0.8
Medication for hormone replacement therapy 2.9 3.3 4.7 2.2 -1.4
Vitamin and mineral supplements 0.4 0.5 0.8 -0.9 0.4
Supplements: Zinc 1.7 1.9 3.6 1.9 -0.3
Medication: Co-codamol 0.2 0.2 0.3 0.3 -0.5
Medication: Metformin 11.4 16.1 27.0 5.2 -2.3
Diabetes (father) 1.8 2.3 4.5 2.1 -0.3
Diabetes (mother) 0.5 0.7 0.8 0.8 -0.9
Severe depression (siblings) 1.0 1.1 2.1 -0.0 -1.5
Pack years adult smoking proportion 2.0 3.0 4.4 1.3 -2.1
Impedance of leg (right) 1.3 6.4 11.0 -3.3 1.3
Leg fat-free mass (left) 0.1 0.7 0.8 0.8 -0.9
Trunk fat percentage 0.2 0.9 1.0 -1.0 -0.8
Hand grip strength (right) 0.2 0.7 1.3 -1.1 0.3
Townsend deprivation index at recruitment 0.0 0.0 0.0 -0.1 0.1
Current tobacco smoking 0.6 1.0 1.9 -1.4 0.2
Average weekly fortified wine intake 1.6 1.9 2.3 -1.2 -1.5
Maternal smoking around birth 4.2 6.0 8.1 2.0 -2.8
Fed-up feelings 1.7 3.2 4.3 1.4 -2.1
Frequency of unenthusiasm / disinterest in last 2 weeks 0.9 1.2 2.3 0.0 -1.5
Relative age voice broke 0.8 1.2 1.3 -1.1 1.0
Taking other prescription medications 8.6 13.3 17.7 4.2 -3.0
Age when periods started (menarche) 3.7 8.9 13.6 2.0 -3.7
Bilateral oophorectomy (both ovaries removed) 0.5 0.6 0.8 0.6 -0.9
Heel bone mineral density (BMD) T-score, automated (left) 3.2 7.4 10.1 -3.2 2.1
Tinnitus: Yes, but not now, but have in the past 1.6 1.7 2.8 -1.7 0.7
Qualifications: CSEs or equivalent 1.1 1.5 1.7 -1.3 -1.1
Serious illness, injury or assault to yourself 1.9 2.2 4.5 2.1 -0.0
High blood pressure 7.5 20.9 31.4 5.6 -3.2
Hayfever, allergic rhinitis or eczema 8.6 18.7 30.0 2.7 -5.5
Multivitamins +/- minerals 0.1 0.2 0.3 0.1 -0.5
Stomach or abdominal pain in last month 0.1 0.1 0.3 -0.5 -0.0
Supplements: Glucosamine 2.2 2.8 4.0 1.3 -2.0
Diverticular disease/diverticulitis (self-reported) 0.0 0.1 0.1 0.3 -0.2
Medication: Atenolol 1.2 1.5 2.4 1.6 -0.8
Medication: Levothyroxine sodium 0.1 0.2 0.3 -0.5 -0.3
Sitting height 1.0 7.3 12.9 -3.6 1.3
Chronic bronchitis/emphysema (father) 0.7 0.8 1.4 -1.2 -0.6
High blood pressure (mother) 0.4 0.5 0.7 0.6 -0.9
Body mass index (BMI) 1.5 6.4 6.5 2.5 -2.5
Impedance of leg (left) 1.4 7.0 11.9 -3.4 1.5
Leg predicted mass (left) 0.1 0.8 0.9 0.8 -1.0
Trunk fat mass 0.2 0.8 1.3 -0.5 -1.1
Waist circumference 0.1 0.4 0.6 0.8 -0.5
Number of incorrect matches in round 0.0 0.1 0.1 0.4 0.0
Past tobacco smoking 0.2 0.4 0.5 -0.7 0.6
Alcohol usually taken with meals 0.9 1.4 1.6 1.3 1.1
Nervous feelings 0.8 1.5 2.9 0.2 1.7
Frequency of tenseness / restlessness in last 2 weeks 0.2 0.2 0.5 -0.1 0.7
Hearing difficulty/problems with background noise 1.6 2.6 4.9 0.6 -2.2
Hair/balding pattern: Pattern 2 0.5 0.7 1.2 -0.3 -1.1
Had menopause 0.9 1.1 2.0 1.4 -0.5
Had other major operations 0.7 0.9 1.3 1.1 -0.7
Forced vital capacity (FVC) 1.1 4.3 8.5 -2.9 0.2
Heel bone mineral density (BMD) T-score, automated (right) 1.2 2.7 4.6 -2.1 0.9
Ever unenthusiastic/disinterested for a whole week 0.3 0.3 0.6 0.8 -0.1
Qualifications: None of the above 2.0 4.3 8.5 2.9 -0.4
Financial difficulties in last 2 years 0.1 0.1 0.2 -0.5 0.1
Mouth/teeth dental problems 2.8 4.3 6.1 -1.6 2.5
Heart attack 0.2 0.3 0.6 -0.8 -0.2
Allergy 8.6 19.7 28.0 -3.4 5.3
Pain all over the body in last month 0.7 0.7 1.3 1.1 0.3
Diabetes (self-reported) 5.7 8.8 13.7 3.7 -2.0
Hayfever/allergic rhinitis (self-reported) 1.9 2.6 4.5 0.8 -2.1
Medication: Ramipril 8.0 10.2 14.4 3.8 -2.5
Medication: Simvastatin 1.4 2.1 2.4 1.3 -1.5
Fluid intelligence score 1.1 2.2 3.8 -1.9 -0.8
Illnesses of siblings 3.0 4.2 4.6 -1.9 2.1
Neuroticism score 1.0 2.0 2.8 1.7 -1.1
Weight 0.3 1.2 2.0 0.7 -1.4
Impedance of arm (right) 7.2 33.5 42.3 -6.5 5.0
Arm fat percentage (right) 0.0 0.1 0.2 0.3 -0.4
Trunk fat-free mass 0.4 2.5 3.3 1.3 -1.8
Hip circumference 0.1 0.5 0.9 0.4 -0.9
Time employed in main current job 0.6 0.7 1.3 -0.4 1.1
Alcohol intake versus 10 years previously 0.8 1.2 1.6 1.3 -0.9
Father’s age at death 0.0 0.0 0.1 -0.0 -0.3
Worrier / anxious feelings 0.9 1.6 3.1 1.8 -0.3
Frequency of tiredness / lethargy in last 2 weeks 2.9 4.7 7.5 2.7 -1.4
Falls in the last year 0.8 1.1 1.1 1.0 1.0
Hair/balding pattern: Pattern 3 0.2 0.3 0.4 0.5 0.6
Number of live births 10.8 15.3 17.2 3.7 -4.1
Forced expiratory volume in 1-second (FEV1) 0.7 2.5 4.8 -2.2 -0.4
Pulse rate 2.5 4.3 5.4 2.3 -1.8
Happiness 1.4 1.7 2.3 1.1 -1.5
Noisy workplace 0.1 0.2 0.3 0.1 -0.6
Qualifications: A levels/AS levels or equivalent 0.4 0.9 1.7 -1.3 0.2
Serious illness, injury or assault of a close relative in last 2 years 0.1 0.1 0.2 0.3 0.4
Mouth/teeth dental problems: Dentures 0.5 0.9 1.8 0.1 -1.3
Asthma 3.0 5.8 6.0 2.4 -2.4
Medication: Ibuprofen (e.g. Nurofen) 1.1 1.4 1.8 1.3 -1.1
Medication: Cholesterol lowering 2.5 3.8 5.6 2.4 -1.4
Depression (self-reported) 0.5 0.5 1.1 1.0 0.2
Medication: Lansoprazole 1.7 1.9 2.7 1.6 -1.1
Prospective memory result 0.7 0.9 1.4 1.2 0.6
Lung cancer (father) 1.3 1.5 2.9 -0.2 -1.7
Illnesses of mother 0.2 0.3 0.3 -0.5 -0.5
Forced expiratory volume in 1-second (FEV1), Best measure 0.6 2.0 3.8 -2.0 -0.4
Pulse wave Arterial Stiffness index 1.6 1.9 2.5 1.6 -1.1
Impedance of arm (left) 8.4 38.9 48.9 -7.0 5.4
Arm fat mass (right) 0.2 0.9 1.3 0.7 -1.2
Trunk predicted mass 0.4 2.4 3.2 1.2 -1.8
Standing height 0.9 8.8 13.7 -3.7 2.0
Length of working week for main job 0.1 0.1 0.2 0.5 0.3
Exposure to tobacco smoke at home 0.4 0.5 0.5 0.7 -0.7
Breastfed as a baby 0.0 0.0 0.0 -0.1 -0.2
Tense / ‘highly strung’ 0.1 0.1 0.2 0.2 0.5
Seen doctor (GP) for nerves, anxiety, tension or depression 2.0 3.0 4.6 2.1 -1.2
Hair/balding pattern: Pattern 4 1.6 3.9 5.1 -2.3 1.7
Birth weight of first child 0.4 0.7 1.2 -0.4 1.1
Peak expiratory flow (PEF) 1.3 2.9 3.6 1.5 -1.9
Pulse wave reflection index 0.2 0.3 0.3 0.6 -0.5
Ever highly irritable/argumentative for 2 days 0.9 1.1 2.0 0.4 -1.4
Loud music exposure frequency 0.5 0.5 0.7 -0.8 0.6
Qualifications: O levels/GCSEs or equivalent 1.9 3.0 6.0 -2.4 0.3
Mouth/teeth dental problems: Bleeding gums 0.5 0.6 1.3 0.2 1.1
Blood clot in the leg (DVT) 0.2 0.3 0.6 -0.8 -0.0
Medication: Paracetamol 3.9 6.5 10.7 3.3 -1.5
Headache pain in last month 6.3 10.8 15.8 4.0 -2.4
Medication for cholesterol, blood pressure or diabetes 9.5 15.7 23.2 -4.8 2.9
Glaucoma (self-reported) 0.8 1.0 1.8 1.3 0.4
Gout (self-reported) 2.4 3.3 6.1 0.7 -2.5
Hypothyroidism/myxoedema (self-reported) 0.2 0.4 0.7 0.2 -0.8
Medication: Amlodipine 5.5 7.7 9.5 3.1 -2.4
Medication: Ventolin 100micrograms inhaler 4.1 5.2 6.2 2.1 -2.5
Birth weight 2.0 4.2 5.2 -1.8 2.3
Chronic bronchitis/emphysema (mother) 1.2 1.4 2.2 1.5 -0.7
High blood pressure (siblings) 0.9 1.2 2.0 1.4 -0.7
Forced vital capacity (FVC), Best measure 0.7 2.5 5.0 -2.2 0.3
Body fat percentage 0.1 0.5 0.9 -0.2 -0.9
Leg fat percentage (right) 0.7 2.7 3.2 1.5 -1.8
Arm fat-free mass (right) 1.3 6.6 8.6 2.2 -2.9
Exposure to tobacco smoke outside home 0.5 0.6 1.3 -1.1 0.0
Comparative body size at age 10 0.0 0.1 0.1 0.3 0.0
Number of full brothers 2.9 3.6 5.0 1.5 -2.2
Worry too long after embarrassment 0.6 0.9 1.5 1.2 -0.6
Seen a psychiatrist for nerves, anxiety, tension or depression 0.1 0.1 0.2 -0.4 0.4
Wheeze or whistling in the chest in last year 2.6 4.7 5.1 2.0 -2.3
Number of children fathered 2.3 2.6 4.5 0.8 -2.1
Reason for reducing amount of alcohol drunk: Health precaution 8.9 10.4 10.6 -3.2 3.3
Age at first live birth 1.9 3.4 4.3 -1.6 2.1
Pulse wave peak to peak time 2.1 2.5 3.7 -1.9 1.1
Health satisfaction 3.8 4.9 6.8 2.6 -1.8
Shortness of breath walking on level ground 1.8 2.2 4.4 0.2 -2.1
Qualifications: College or University degree 0.4 1.3 2.3 -1.5 0.6
Eye problems/disorders: None of the above 0.8 0.9 1.8 -1.3 0.2
Mouth/teeth dental problems: Loose teeth 1.4 1.7 3.4 -1.9 -0.0
Emphysema/chronic bronchitis 0.9 1.0 1.4 1.2 -0.8
Medication for pain relief, constipation, heartburn 6.9 11.8 14.3 -3.8 3.0
Neck or shoulder pain in last month 1.3 1.8 3.3 0.7 -1.8
Medication: Blood pressure 11.3 19.9 30.1 5.5 -3.1
Angina (self-reported) 0.4 0.5 0.9 0.3 -1.0
Migraine (self-reported) 3.9 4.8 9.4 3.1 -0.4
Medication: Ibuprofen 2.4 2.8 3.1 1.6 -1.8
Medication: Allopurinol 1.5 2.0 2.9 1.0 -1.7
Medication: Omeprazole 0.8 1.0 2.0 1.4 0.1
Medication: Seretide 50 evohaler 0.3 0.4 0.6 -0.8 0.3
Mean time to correctly identify matches 1.0 1.9 2.9 -0.9 1.7
Heart disease (mother) 0.0 0.1 0.1 0.1 -0.3
Reproduciblity of spirometry measurement using ERS/ATS criteria 0.4 0.5 0.7 -0.8 -0.6
Whole body fat mass 0.2 0.9 1.8 0.2 -1.3
Leg fat mass (right) 0.7 2.8 3.5 1.4 -1.9
Arm predicted mass (right) 1.3 6.8 9.5 2.0 -3.1
Pulse rate, automated reading 0.5 1.7 2.0 1.2 -1.4
Alcohol intake frequency. 5.4 12.6 14.8 3.2 -3.8
Comparative height size at age 10 1.5 8.0 8.5 -2.9 2.8
Number of full sisters 1.1 1.3 2.6 0.2 -1.6
Suffer from ‘nerves’ 0.3 0.5 1.1 0.1 -1.0
Overall health rating 3.3 7.1 12.3 3.5 -1.4
Chest pain or discomfort 1.7 2.4 2.9 1.7 -1.4
Had major operations 2.5 2.9 4.4 1.2 -2.1
Age at last live birth 0.7 1.1 1.6 -0.7 1.3
Family relationship satisfaction 1.2 1.4 2.7 0.4 -1.6
Leg pain on walking 1.7 2.1 2.2 1.5 -1.4
Qualifications: NVQ or HND or HNC or equivalent 0.5 0.6 1.2 -0.0 -1.1
Commuting to job workplace: Car/motor vehicle 0.2 0.2 0.5 -0.1 -0.7
Illness, injury, bereavement, stress in last 2 years 1.7 2.1 4.1 -2.0 0.2
Medication: Aspirin 3.8 5.0 5.2 2.3 -2.2
Supplements: Vitamin C 0.5 0.5 0.8 0.9 -0.5
Knee pain experienced in last month 0.3 0.4 0.7 0.3 -0.9
Hypertension (Self-reported) 7.9 21.9 32.7 5.7 -3.3
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 0.0 0.0 0.0 -0.1 0.1
Illnesses of father: Heart disease 0.1 0.2 0.3 -0.6 -0.1
Illnesses of siblings: Diabetes 2.8 3.5 5.4 1.3 -2.3
Smoking status: Previous 0.2 0.3 0.5 0.7 -0.4
Forced expiratory volume in 1-second (FEV1), predicted 4.8 9.9 12.8 -3.6 2.7
Whole body fat-free mass 0.4 2.4 3.2 1.3 -1.8
Leg fat-free mass (right) 0.1 0.4 0.4 0.6 -0.7
Arm fat percentage (left) 0.0 0.1 0.1 0.0 -0.3
Average weekly red wine intake 2.1 3.2 3.9 -1.6 2.0
Handedness (chirality/laterality): Left-handed 0.9 1.1 1.7 0.7 -1.3
Mood swings 1.9 3.4 6.3 2.5 -0.7
Loneliness, isolation 1.0 1.4 2.0 1.4 -0.8
Long-standing illness, disability or infirmity 1.2 1.9 3.3 1.8 -0.7
Ever had bowel cancer screening 1.4 1.7 3.3 1.8 -0.2
Diabetes diagnosed by doctor 8.1 13.3 20.5 4.5 -2.5
Ever had stillbirth, spontaneous miscarriage or termination 0.3 0.3 0.6 -0.1 0.8
Friendships satisfaction 1.3 1.6 3.1 -1.8 -0.4
Qualifications: nursing, teaching 0.1 0.2 0.2 0.5 -0.3
Commuting to job workplace: Walk 1.4 1.5 1.7 -1.3 1.1
Eye problems/disorders: Cataract 0.1 0.1 0.2 0.2 -0.4
Mouth/teeth dental problems: Mouth ulcers 5.5 8.7 13.8 1.9 -3.7
Medication for cholesterol 6.4 9.7 15.9 -4.0 1.9
Medication: Laxatives (e.g. Dulcolax, Senokot) 1.9 2.2 4.4 0.1 -2.1
Back pain experienced in last month 0.1 0.2 0.3 -0.0 0.6
Mineral and other dietary supplements 1.2 1.6 2.1 -1.4 1.1
Breast cancer (self-reported) 0.2 0.2 0.5 -0.7 0.1
Asthma (self-reported) 3.7 7.4 8.1 2.6 -2.8
Osteoporosis (self-reported) 0.3 0.3 0.5 -0.4 0.7
Osteoarthritis (self-reported) 0.2 0.3 0.4 0.6 -0.4
Medication: Aspirin 5.0 6.5 7.0 2.6 -2.5
Medication: Gliclazide 6.6 7.4 10.7 3.3 -2.0
Illnesses of father: None of the above (group 1) 0.1 0.1 0.2 0.2 0.5
Smoking status: Current 0.7 1.2 2.3 -1.5 0.1
Forced expiratory volume in 1-second (FEV1), predicted percentage 0.4 0.8 1.2 0.6 -1.1
Whole body water mass 0.5 2.7 3.5 1.4 -1.9
Leg predicted mass (right) 0.1 0.3 0.3 0.5 -0.6
Arm fat mass (left) 0.2 0.9 1.3 0.7 -1.1
Number of self-reported non-cancer illnesses 7.8 13.6 21.9 4.7 -2.3
Average weekly champagne plus white wine intake 0.3 0.5 0.8 0.9 -0.3
Miserableness 0.3 0.5 0.5 -0.6 0.7
Guilty feelings 1.2 1.8 1.9 1.3 -1.4
Wears glasses or contact lenses 0.1 0.1 0.2 0.5 -0.1
Ever taken oral contraceptive pill 0.5 0.6 0.9 1.0 -0.5
Hearing aid user 3.1 3.5 4.2 2.1 -1.6
Mother’s age at death 0.7 0.9 1.7 1.3 0.3
Financial situation satisfaction 0.2 0.3 0.6 -0.8 0.1
Tinnitus: Yes, now most or all of the time 0.0 0.0 0.0 0.1 -0.2
Commuting to job workplace: Public transport 0.2 0.2 0.2 0.4 0.5
Eye problems/disorders: Glaucoma 1.6 1.9 3.6 1.9 0.4
Medication: Blood pressure 4.6 8.7 14.6 3.8 -1.7
Pain type(s) experienced in last month: Hip pain 0.1 0.1 0.1 0.3 0.3
Supplements: Fish oil (including cod liver oil) 0.1 0.1 0.1 0.2 -0.3
High cholesterol (Self-reported) 0.1 0.1 0.1 0.4 0.2
Medication: Bendroflumethiazide 3.6 5.4 10.6 3.2 -0.6
Medication: Paracetamol 4.9 7.5 13.2 3.6 -1.4
Medication: Lisinopril 2.9 3.7 7.3 2.7 0.4
Medication: Atorvastatin 2.0 2.5 4.6 2.1 -0.6
Illnesses of father: High blood pressure 0.8 1.0 1.4 0.8 -1.2
Alcohol drinker status: Never 1.9 2.3 2.3 1.5 -1.5
Ever smoked 0.1 0.1 0.2 -0.2 -0.5
Basal metabolic rate 0.3 1.9 2.8 1.0 -1.7
Leg fat percentage (left) 0.8 2.8 3.6 1.4 -1.9
Arm fat-free mass (left) 1.5 7.7 10.1 2.3 -3.2
Number of operations (self-reported) 3.8 5.7 7.1 2.7 -2.1
Average weekly beer plus cider intake 3.3 4.8 6.1 -2.5 1.9
Irritability 0.0 0.1 0.1 0.3 -0.2
Risk taking 0.3 0.4 0.7 0.1 -0.9
Ever had prostate specific antigen (PSA) test 1.0 1.2 1.4 1.0 -1.2
Fractured/broken bones in last 5 years 1.2 1.6 3.1 1.8 0.2
Age started oral contraceptive pill 0.0 0.0 0.0 0.1 -0.0
Diastolic blood pressure, automated reading 2.9 9.1 12.5 3.5 -2.4
Ever depressed for a whole week 0.7 0.8 1.6 0.2 -1.3
Unable to work because of sickness or disability 0.2 0.3 0.3 0.6 -0.5
Commuting to job workplace: Cycle 0.2 0.3 0.4 0.4 0.6
Myopia 0.1 0.1 0.1 -0.2 -0.4
Vascular/heart problems diagnosed by doctor 8.6 23.5 35.6 -6.0 3.4
Cholesterol lowering medication 0.2 0.3 0.7 0.8 -0.1
Medication: Omeprazole (e.g. Zanprol) 1.3 1.5 2.6 1.6 -0.7
Pain experienced in last month 3.5 5.8 6.7 -2.6 2.2
Supplements: Calcium 0.4 0.5 0.7 0.4 -0.9
Basal cell carcinoma (self-reported) 0.6 0.7 1.0 1.0 -0.6
Heart attack/myocardial infarction (self-reported) 0.3 0.4 0.8 -0.9 -0.0
Deep venous thrombosis (DVT) (self-reported) 0.2 0.2 0.5 -0.7 0.0
Heart disease (siblings) 1.1 1.4 1.7 -1.0 -1.3
Alcohol drinker status: Previous 1.9 2.1 2.4 1.6 -1.3
Pack years of smoking 3.0 4.4 6.4 1.6 -2.5
Impedance of whole body 4.6 23.4 33.8 -5.8 3.6
Leg fat mass (left) 0.8 3.1 4.1 1.4 -2.0
Arm predicted mass (left) 1.5 7.4 9.7 2.3 -3.1