Hub : Genes

MANBA

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.0840	0.0410	3.5e-05	0.044	0.028	0.012	0.031	0.027	4.0e-06	2.2e-04	1.2e-02	9.6e-05	2.4e-04
2	GTEx	Brain Cerebellum	0.1790	0.0770	2.2e-03	0.026	NA	0.052	NA	0.022	5.9e-02	NA	1.2e-02	NA	7.1e-02
3	GTEx	Cells Transformed fibroblasts	0.2620	0.0550	0.0e+00	0.220	NA	0.268	NA	0.271	2.0e-16	NA	3.5e-20	NA	1.9e-20
4	GTEx	Pancreas	0.1430	0.0650	3.8e-03	0.142	NA	0.058	NA	0.022	1.4e-06	NA	1.8e-03	NA	3.9e-02
5	GTEx	Skin Sun Exposed Lower leg	0.1130	0.0440	8.0e-05	0.032	NA	0.044	NA	0.045	1.1e-03	NA	1.6e-04	NA	1.3e-04
6	GTEx	Spleen	0.2850	0.0970	4.3e-05	0.233	NA	0.298	NA	0.286	1.1e-06	NA	2.3e-08	NA	4.8e-08
7	NTR	Blood	0.0107	0.0073	2.2e-02	0.001	0.005	0.001	0.006	-0.001	9.3e-02	5.7e-03	1.4e-01	3.1e-03	5.4e-01
8	ROSMAP	Brain Pre-frontal Cortex	0.1967	0.0392	0.0e+00	0.303	0.279	0.309	0.278	0.306	1.9e-39	5.3e-36	2.3e-40	7.2e-36	5.2e-40
9	YFS	Blood	0.0881	0.0223	0.0e+00	0.097	0.088	0.092	0.095	0.097	3.6e-30	3.1e-27	1.2e-28	2.7e-29	5.2e-30
10	TCGA	Bladder Urothelial Carcinoma	0.1000	0.0400	1.5e-07	0.127	0.096	0.107	NA	0.109	7.1e-11	1.7e-08	2.6e-09	NA	1.8e-09
11	TCGA	Breast Invasive Carcinoma	0.1120	0.0325	0.0e+00	0.157	0.150	0.162	NA	0.163	6.9e-31	1.6e-29	7.3e-32	NA	3.3e-32
12	TCGA	Colon Adenocarcinoma	0.3270	0.1000	7.3e-11	0.108	0.195	0.212	NA	0.135	8.9e-07	1.9e-11	2.0e-12	NA	3.5e-08
13	TCGA	Glioblastoma Multiforme	0.2670	0.1300	8.2e-03	-0.001	0.029	-0.004	NA	-0.008	3.5e-01	4.5e-02	4.6e-01	NA	6.4e-01
14	TCGA	Head and Neck Squamous Cell Carcinoma	0.1537	0.0562	9.5e-10	0.093	0.068	0.082	NA	0.094	1.4e-10	4.1e-08	1.5e-09	NA	1.0e-10
15	TCGA	Kidney Renal Clear Cell Carcinoma	0.0336	0.0159	5.3e-05	0.033	0.041	0.035	NA	0.026	1.0e-04	2.0e-05	7.9e-05	NA	6.2e-04
16	TCGA	Brain Lower Grade Glioma	0.0968	0.0403	2.1e-04	-0.001	0.000	0.017	NA	0.005	4.6e-01	3.3e-01	4.7e-03	NA	8.4e-02
17	TCGA	Lung Adenocarcinoma	0.1277	0.0432	2.3e-12	0.097	0.103	0.098	NA	0.097	2.0e-11	4.5e-12	1.6e-11	NA	2.1e-11
18	TCGA	Lung Squamous Cell Carcinoma	0.0718	0.0307	5.0e-05	0.038	0.030	0.027	NA	0.025	3.6e-05	2.2e-04	4.7e-04	NA	7.5e-04
19	TCGA	Prostate Adenocarcinoma	0.1089	0.0451	3.5e-06	0.042	0.023	0.033	NA	0.041	2.8e-05	1.6e-03	1.9e-04	NA	3.5e-05
20	TCGA	Stomach Adenocarcinoma	0.2820	0.0720	1.1e-10	0.116	0.138	0.127	NA	0.116	9.7e-09	3.7e-10	1.9e-09	NA	1.0e-08
21	TCGA	Thyroid Carcinoma	0.1170	0.0480	2.4e-06	0.061	0.055	0.059	NA	0.055	1.4e-06	4.6e-06	1.9e-06	NA	4.2e-06

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18	19	20	21
Bipolar Disorder (2018)	0.3	0.4	2.1	-0.9	-0.0	-0.0	0.9	0.2	0.3	0.6	-0.2	-0.9	0.7	0.5	0.8	1.4	-0.0	0.0	1.4	0.5	0.3	0.4	0.4	-0.2
Bipolar Disorder or Schizophrenia	2.2	5.3	11.5	0.7	-2.3	2.5	-0.9	-1.1	-2.2	2.4	-2.4	0.8	2.6	2.7	2.8	2.5	2.5	2.6	2.7	3.4	1.8	2.3	2.6	2.3
Depressed Affect (Nagel 2018)	1.5	3.2	6.3	-1.8	2.3	-2.1	1.2	1.4	1.3	-1.8	1.8	-1.3	-2.1	-2.1	-2.5	-1.5	-1.8	-2.2	-1.2	-2.4	-0.7	-1.8	-1.1	-1.6
Depression (Nagel 2018)	1.1	1.7	4.7	-2.2	1.8	-1.4	1.0	1.1	0.9	-0.7	1.1	-0.8	-1.6	-1.6	-2.1	-0.8	-1.1	-1.5	-1.0	-1.7	-0.5	-1.4	-0.5	-0.9
Intelligence (Savage-Jansen 2018)	1.9	5.9	11.8	1.8	-0.5	2.5	0.5	0.9	-3.0	2.0	-2.5	-0.4	2.5	2.9	2.2	2.7	3.2	1.9	2.1	2.9	3.4	3.2	3.3	2.7
Neuroticism (Nagel 2018)	0.7	1.7	5.9	-1.1	1.7	-1.4	1.2	1.4	0.0	-1.4	1.4	-1.4	-1.7	-1.4	-2.4	-1.1	-0.9	-1.8	-0.9	-1.7	0.5	-1.1	-0.2	-0.7
Schizophrenia (2018)	3.4	7.2	15.4	1.6	-3.0	3.2	-1.8	-1.5	-3.0	2.5	-2.9	1.8	2.7	3.0	3.1	2.1	3.2	3.3	2.4	3.9	2.1	0.0	3.0	3.1
Schizophrenia vs Biploar Disorder	0.6	0.8	3.8	0.9	-0.3	0.9	-1.2	-1.9	-1.2	0.2	-0.7	1.2	0.0	0.5	0.8	0.1	0.6	1.2	-1.3	0.7	0.9	0.3	0.5	1.1
Worry (Nagel 2018)	0.3	0.7	5.3	0.2	0.7	0.5	-0.0	0.4	-1.8	-0.3	-0.2	-0.1	-0.3	0.3	-1.0	0.6	0.8	0.2	-0.6	-0.0	2.3	0.4	1.0	1.4
Alzheimer’s Disease (in mother)	0.2	0.2	1.8	0.7	-0.2	0.0	-0.7	-0.3	0.1	0.6	-0.2	0.6	0.0	0.1	0.2	-1.4	-0.2	-0.1	-0.2	-0.2	-0.6	0.2	-0.6	-0.2
Alzheimer’s Disease (in father)	0.3	0.3	2.0	0.0	0.2	-0.3	-0.3	0.4	0.7	-1.4	0.7	0.3	-0.3	-0.5	-0.7	-0.8	-0.7	-0.0	0.1	-0.3	-0.6	-0.4	-0.9	-0.3
Alzheimer’s Disease (including proxy)	0.2	0.3	1.9	0.9	-0.5	0.2	-1.1	-0.5	0.3	-0.7	0.1	0.6	0.1	0.1	0.1	-1.4	-0.3	0.1	0.0	-0.1	-0.7	0.2	-0.9	-0.2
Crohns Disease (2017)	1.5	3.3	12.5	-3.5	1.6	-1.8	1.9	0.7	2.0	-1.3	2.0	-2.1	-1.6	-2.0	-0.7	-1.5	-1.4	-2.0	1.7	-0.6	-2.4	-2.3	-0.3	-1.7
Irritable Bowel Disease (IBD)	0.5	1.3	4.5	0.3	-1.3	1.2	-1.4	-0.8	-0.7	0.4	-1.1	1.2	1.3	1.1	2.1	0.1	1.0	1.6	0.8	1.8	0.2	1.0	0.6	1.1
Ulcerative Colitis (UC)	5.0	9.3	17.4	3.3	-3.2	3.4	-3.6	-1.9	-3.0	1.7	-3.4	3.5	3.5	3.6	3.7	1.9	2.8	4.2	-0.3	3.1	2.7	3.6	1.4	3.3
Major Depression (MDD)	0.3	0.4	1.5	-0.3	-0.9	0.3	0.3	0.9	-0.3	0.3	-0.6	-0.3	1.0	0.8	0.2	0.9	0.5	0.1	0.7	0.0	1.2	1.1	0.1	0.4
Reaction Time	1.5	2.8	5.2	1.5	-2.0	2.0	-1.7	-1.7	-2.3	1.9	-1.5	1.6	0.5	1.1	2.0	-0.6	1.7	1.6	0.1	1.6	1.5	1.4	2.3	2.3
Verbal and Numeric Reasoning (VNR)	0.6	1.4	3.5	0.8	0.7	1.1	1.1	0.9	-1.3	1.0	-1.2	-1.0	0.8	1.2	1.4	1.3	1.5	0.4	1.2	1.4	1.4	1.3	1.9	1.5
Breast Cancer	0.9	2.2	7.4	0.5	0.6	1.5	0.6	0.8	-0.8	0.8	-1.2	-0.6	2.5	1.9	0.9	2.1	1.6	1.2	2.7	1.3	1.4	2.2	1.7	1.1
Ovarian Cancer	0.5	0.7	2.2	0.7	-0.5	0.8	-0.5	-1.1	-0.6	1.1	-0.8	0.5	1.0	0.9	1.2	-0.4	0.7	0.5	1.0	0.8	0.2	0.6	1.5	0.3
Prostate Cancer	0.5	0.7	3.1	1.8	-1.2	0.6	-1.0	-1.1	-0.9	0.2	-0.7	1.0	0.2	0.4	0.1	-1.5	0.6	0.4	-0.5	0.4	0.3	0.4	0.7	0.3
Age at First Birth	0.2	0.3	1.8	-0.7	-0.5	-0.1	1.0	-0.3	0.1	0.1	-0.2	-0.8	-0.1	-0.2	-0.1	-0.4	0.3	-0.6	1.3	0.5	-0.2	-0.3	0.7	-0.2
Bipolar Disorder (2011)	0.8	0.8	3.8	-1.2	-0.4	-0.4	1.9	1.3	0.1	1.0	-0.3	-1.9	0.2	0.1	0.1	1.7	-0.4	-0.7	0.6	0.1	0.5	0.0	0.0	-0.8
Body Mass Index (BMI) (2010)	4.2	5.8	13.1	-2.6	2.6	-2.8	1.9	2.4	2.6	-3.6	2.8	-1.9	-2.2	-2.5	-2.6	-0.3	-2.6	-2.4	-1.3	-2.6	-1.5	-2.8	-2.4	-2.4
Coronary Artery Disease (CAD)	0.5	0.6	1.9	1.0	-1.4	0.4	-1.2	-1.2	-0.9	-0.8	0.6	1.1	0.3	0.5	0.2	0.2	0.4	1.0	-0.8	0.4	0.3	0.7	-0.1	0.9
Crohns Disease (2012)	2.8	4.6	9.9	-3.2	2.6	-2.6	1.7	0.8	2.2	-1.5	2.8	-1.7	-2.4	-2.5	-2.0	-1.1	-2.2	-2.4	-0.8	-2.1	-2.1	-2.8	-1.5	-2.1
Mean Putamen Volume	1.2	1.3	2.8	0.4	-1.4	1.1	-0.1	-0.8	-0.9	0.4	-1.4	0.1	1.6	1.4	1.7	1.0	1.1	1.0	1.5	1.5	1.1	1.2	1.7	0.8
Fasting Glucose	6.6	7.8	16.4	-2.5	3.0	-3.2	2.4	4.0	2.5	-2.2	2.6	-3.8	-3.2	-3.2	-3.0	-0.7	-2.9	-3.5	-0.4	-2.6	-1.5	-3.2	-2.2	-3.1
HbA1C	2.6	2.9	6.8	-1.4	1.7	-2.0	0.8	0.8	1.8	-2.1	1.9	-1.6	-1.8	-1.9	-1.2	-1.0	-1.9	-2.2	-0.0	-1.6	-1.9	-2.6	-1.3	-2.1
HDL Cholesterol	1.2	1.9	7.7	2.8	-1.6	1.0	-1.6	-0.7	-1.5	2.3	-1.3	1.6	0.9	1.2	1.2	0.9	0.9	1.6	-1.7	0.8	0.9	1.3	0.4	0.9
LDL Cholesterol	0.2	0.3	1.6	0.1	0.1	0.4	0.9	0.7	-0.8	-0.7	-0.4	-0.9	0.0	0.2	0.0	0.6	0.2	-0.1	0.4	0.3	1.2	0.2	0.7	0.5
Lupus	0.7	1.0	4.2	1.0	-1.0	0.0	-1.9	-2.0	-0.1	0.3	0.5	1.9	-0.4	-0.2	0.5	-1.5	-0.4	0.6	-1.6	-0.1	-1.0	-0.4	-0.7	0.2
Neuroticism (2016)	0.9	1.3	4.4	-1.2	1.0	-1.3	1.1	1.7	0.7	-2.1	1.0	-1.0	-0.8	-0.9	-1.1	-0.4	-1.1	-1.4	-0.9	-1.7	0.0	0.0	-0.9	-1.3
Primary Biliary Cirrhosis	11.9	17.0	37.5	4.4	-4.7	4.4	-6.1	-5.2	-3.7	3.1	-3.5	6.1	4.1	4.1	2.8	1.8	4.4	5.5	-1.7	3.6	3.3	4.1	1.7	4.1
Rheumatoid Arthritis	1.0	1.4	9.1	3.0	-1.8	0.0	0.0	-2.9	0.0	2.3	-1.6	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Schizophrenia (2014)	4.0	8.8	16.8	1.2	-3.4	3.2	-1.0	-1.2	-3.1	2.6	-3.2	0.9	3.2	3.4	3.5	3.6	3.2	3.5	2.9	4.1	2.8	3.1	3.2	3.2
Triglycerides	0.7	1.2	5.2	-0.8	0.4	-0.3	-1.6	-0.9	-0.0	-2.2	1.0	1.6	-0.8	-0.7	-1.6	-2.3	-0.3	-0.1	-1.1	-0.7	-0.2	-1.0	-0.8	0.2
Type 2 Diabetes (T2D) (2012)	7.1	8.2	16.2	-2.1	3.1	-3.5	2.5	2.1	2.9	-2.7	3.4	-2.5	-3.4	-3.2	-2.4	-3.4	-2.7	-4.0	-0.6	-3.0	-3.0	-3.2	-1.1	-2.9
Ulcerative Colitis	4.5	6.5	11.5	3.0	-2.4	2.9	-3.1	-1.7	-2.6	1.7	-2.7	3.3	2.9	3.0	2.7	1.6	2.3	3.4	-0.9	2.2	2.4	3.0	0.9	2.7
Blood Eosinophil Count	0.7	5.6	23.4	4.4	-0.7	1.2	-4.8	-4.0	-1.4	-1.0	0.0	4.8	0.8	1.1	0.6	-1.6	1.4	2.5	-3.5	0.4	0.7	1.2	-0.6	1.9
Blood Platelet Count	0.1	1.3	7.3	0.2	1.9	0.2	2.0	1.6	-0.2	0.1	-0.4	-2.0	0.6	0.6	0.9	0.7	0.6	-0.8	2.7	0.4	0.2	1.1	1.5	0.6
Blood Red Count	0.8	7.7	22.4	-3.3	2.8	-2.2	4.6	3.8	2.9	-1.3	1.7	-4.7	-1.8	-2.2	-0.3	-1.7	-2.1	-3.6	4.2	-1.2	-3.0	-1.9	0.3	-2.5
Blood White Count	0.5	4.0	23.1	1.2	-0.1	0.8	-4.4	-4.8	0.3	-0.8	0.4	4.4	0.6	0.3	0.3	-2.1	0.3	2.1	-2.5	-0.0	-0.7	0.4	-1.5	0.6
Heel T-Score	0.9	7.0	14.7	0.7	-1.5	2.9	0.2	0.4	-1.8	2.9	-3.5	-0.2	3.8	3.3	2.6	3.8	2.7	2.2	3.8	2.5	2.6	3.4	2.8	2.1
BMI	2.7	15.5	37.3	-4.5	2.8	-4.5	2.3	2.3	4.4	-6.1	4.8	-2.3	-4.3	-4.6	-4.4	-3.3	-4.4	-3.8	-2.2	-4.2	-3.0	-4.0	-3.5	-4.4
Height	0.6	12.1	37.9	4.3	-6.2	3.8	-2.8	-1.7	-3.0	4.1	-4.2	2.8	4.2	4.1	2.2	3.0	3.8	3.5	0.1	2.8	3.2	4.0	1.1	3.5
Waist Hip Ratio (WHR)	0.4	1.7	5.8	2.4	0.3	0.1	-2.4	-2.2	-0.7	-0.5	1.0	2.4	-0.8	-0.4	-1.1	-2.0	0.4	0.6	-2.3	-0.2	-0.4	-0.5	-0.4	0.5
Systolic Blood Pressure	0.2	0.9	6.6	2.6	0.1	-0.8	-0.0	0.8	-0.8	0.3	0.6	0.0	-1.3	-0.7	-0.5	-0.4	-0.1	-0.8	-2.1	-0.7	-0.1	-0.6	-0.7	0.0
Smoking Status	0.2	0.5	1.8	0.3	-0.5	0.8	0.3	-0.3	-0.3	0.8	-1.3	-0.3	1.3	1.0	0.3	0.9	0.9	0.1	0.8	0.4	0.8	0.8	0.4	0.3
Allergy or Eczema	7.1	18.7	45.0	-6.5	4.3	-4.5	6.7	5.0	4.0	-2.8	3.3	-6.7	-3.9	-4.1	-2.1	-1.8	-4.4	-5.8	3.0	-3.1	-3.9	-3.9	-0.7	-4.5
Cardiovascular Disease	5.9	19.6	33.2	-1.9	5.4	-5.3	3.5	4.1	3.3	-4.5	5.1	-3.4	-5.8	-5.2	-5.6	-4.1	-4.2	-5.7	-3.0	-5.0	-3.1	-5.2	-3.2	-4.0
Hypothyroidism (self reported)	0.2	0.5	2.4	-0.4	1.0	-0.6	0.0	0.3	0.6	1.6	0.4	-0.0	-0.7	-0.7	-0.4	-1.2	-0.5	-0.9	0.1	-0.9	-1.0	-0.7	-0.5	-0.6
Respiratory disease	3.2	7.0	12.3	-3.1	2.2	-3.3	3.3	2.8	2.5	-2.2	2.7	-3.3	-2.4	-2.7	-2.4	-1.1	-2.9	-3.5	0.5	-2.5	-2.4	-2.9	-1.6	-3.3
Type 2 Diabetes (T2D) (2018)	2.5	4.6	7.8	-2.8	2.7	-2.4	1.4	0.7	1.6	-1.9	2.5	-1.4	-2.8	-2.6	-2.1	-2.3	-2.3	-2.5	-1.1	-2.5	-1.6	-2.6	-1.2	-2.1
Lung FEV1/FVC ratio	0.5	2.6	6.7	-2.0	2.3	-1.6	1.5	0.6	2.5	-0.9	1.2	-1.5	-0.8	-1.5	-1.0	-1.4	-1.6	-2.0	1.0	-1.6	-2.6	-1.2	-0.8	-2.2
Lung FVC	0.2	1.1	3.7	-1.1	0.2	0.9	0.1	-1.1	-0.1	0.8	-0.6	-0.1	1.1	0.8	1.4	1.8	0.5	1.6	1.9	1.7	0.4	0.3	1.3	0.7
Neuroticism	0.6	1.3	4.2	-1.9	2.1	-1.2	1.3	1.1	0.1	-1.0	0.5	-1.4	-1.1	-0.9	-1.5	-0.8	-0.8	-1.7	-0.5	-1.4	0.7	-0.8	0.2	-1.0
Chronotype (morning person)	3.1	7.1	11.2	-1.7	1.9	-3.2	1.9	2.2	2.5	-2.9	3.1	-1.9	-3.3	-3.2	-3.2	-2.0	-3.0	-3.0	-1.3	-2.8	-2.3	-3.3	-2.9	-2.8
Hair Pigment	0.2	5.8	16.7	-0.7	2.1	-2.5	-0.1	-0.4	1.8	-4.1	3.2	0.0	-3.3	-3.1	-3.3	-3.1	-2.1	-2.0	-2.7	-2.7	-1.6	-2.9	-1.8	-1.6
Tanning	0.1	1.1	4.4	-0.1	-0.5	1.3	-0.9	-1.5	-0.7	2.1	-1.0	0.8	1.3	1.1	1.1	-0.7	1.1	0.7	1.0	0.8	-0.1	1.2	1.3	0.7
Hand grip strength (left)	0.8	2.1	10.8	3.3	-3.0	1.1	-0.7	-0.8	-1.1	1.1	-1.3	0.8	1.5	1.4	1.2	1.4	1.3	1.4	-0.3	1.2	1.3	1.2	0.5	1.1
Number of treatments/medications taken	11.8	21.2	34.9	-4.4	5.0	-5.5	3.6	3.1	4.0	-4.4	5.2	-3.6	-5.9	-5.7	-5.5	-4.0	-4.8	-5.7	-2.4	-5.4	-3.6	-5.1	-3.3	-4.4
Average weekly spirits intake	0.3	0.3	2.0	-1.3	0.9	-0.2	0.8	0.2	0.3	0.2	0.2	-0.7	0.5	0.2	0.1	0.1	-0.1	-0.3	1.4	-0.1	-0.3	0.2	0.5	-0.6
Sensitivity / hurt feelings	1.1	1.9	5.1	-1.9	1.0	-1.2	2.1	1.5	-0.8	-1.3	0.9	-2.2	-1.9	-1.1	-1.3	-1.8	-0.5	-2.3	-0.1	-1.0	1.0	-0.9	1.0	-0.4
Frequency of depressed mood in last 2 weeks	1.4	1.9	3.9	-1.5	2.0	-1.6	1.2	1.5	0.9	-0.8	1.0	-1.3	-1.7	-1.7	-1.9	-0.9	-1.2	-1.9	-1.3	-1.7	-0.5	-1.4	-1.0	-1.2
Hearing difficulty/problems: Yes	1.6	2.5	9.6	-1.7	2.1	-1.4	3.0	2.1	1.1	-1.1	0.8	-3.1	-0.9	-1.0	-0.6	0.2	-1.4	-2.0	1.9	-0.9	-0.6	-1.3	0.3	-1.4
Relative age of first facial hair	1.6	3.4	6.2	1.8	-2.5	2.3	-1.7	-1.7	-2.0	2.0	-2.4	1.8	1.6	1.8	1.1	0.2	2.1	1.9	0.6	2.0	1.7	1.9	1.4	2.4
Other serious medical condition/disability diagnosed by doctor	0.9	1.2	4.4	0.8	-1.7	1.0	-2.1	-1.9	-0.9	0.6	-0.7	2.1	0.5	0.7	0.2	-0.7	0.8	1.2	-1.1	0.2	1.1	0.6	0.4	1.0
Ever used hormone-replacement therapy (HRT)	5.9	7.5	12.0	-2.3	1.5	-3.4	2.3	1.8	3.4	-2.0	3.0	-2.2	-3.1	-3.3	-2.6	-2.2	-3.5	-3.3	-0.8	-3.1	-2.7	-2.9	-2.7	-3.5
Ever had hysterectomy (womb removed)	1.0	1.2	4.2	-0.2	-0.4	-1.1	1.5	1.3	-0.3	-0.3	1.3	-1.5	-2.0	-1.4	-1.2	-1.2	-0.8	-1.6	-0.6	-1.1	0.0	-1.1	0.1	-0.4
Systolic blood pressure, automated reading	0.1	0.4	1.0	1.0	0.5	-0.8	0.8	0.3	0.6	0.4	0.5	-0.7	-0.8	-0.7	-0.1	0.3	-0.6	-0.7	-0.2	-0.3	-0.9	-0.6	-0.6	-0.5
Eye problems/disorders: Diabetes related eye disease	1.3	1.5	3.8	-1.5	1.8	-1.2	1.1	1.3	0.9	-2.0	1.3	-1.1	-1.7	-1.6	-1.0	-0.7	-1.0	-1.1	0.0	-0.6	-1.1	-1.3	-0.7	-0.8
Angina	0.5	0.6	1.7	0.6	0.1	-0.9	0.8	1.3	0.9	-0.3	0.5	-0.8	-0.5	-0.7	-1.3	-0.2	-0.8	-1.0	0.2	-0.7	-0.8	-0.7	-1.0	-1.1
Medication for hormone replacement therapy	1.5	1.6	3.9	-0.2	-0.2	-1.7	1.3	0.4	1.3	-1.5	2.0	-1.3	-1.7	-1.5	-1.2	-1.6	-1.1	-1.6	-0.4	-1.1	-0.9	-1.3	-0.7	-1.4
Vitamin and mineral supplements	1.6	2.1	5.7	2.4	-2.0	1.4	-0.5	-0.5	-1.6	0.9	-1.8	0.4	1.5	1.7	1.8	1.1	1.4	1.0	0.2	1.2	2.1	1.8	1.5	1.3
Supplements: Zinc	0.4	0.5	4.9	0.3	-2.2	-0.1	0.3	-0.0	-0.2	-0.6	0.7	-0.3	-0.3	-0.3	-1.1	-1.3	0.3	-0.6	0.1	-0.3	0.0	-0.4	0.1	0.2
Medication: Co-codamol	0.1	0.1	0.4	-0.6	-0.2	-0.0	0.5	-0.0	-0.1	-0.6	0.3	-0.5	-0.4	-0.3	-0.7	-0.1	-0.2	-0.4	0.4	-0.2	0.3	-0.2	0.2	0.2
Medication: Metformin	11.1	15.6	23.8	-3.7	3.6	-4.7	2.3	1.3	4.1	-4.2	4.6	-2.3	-4.7	-4.7	-4.4	-3.6	-4.3	-4.8	-2.3	-4.9	-3.8	-4.8	-3.1	-4.1
Diabetes (father)	0.8	1.0	2.8	0.2	1.1	-1.1	0.3	-0.6	0.8	-1.7	1.6	-0.3	-1.1	-1.0	-1.1	-1.3	-0.8	-1.2	-1.1	-1.4	-0.5	-1.1	-0.2	-0.8
Diabetes (mother)	1.2	1.5	3.3	-1.8	1.0	-1.2	0.9	0.3	1.4	-1.2	1.0	-0.9	-1.2	-1.4	-1.6	-1.2	-1.3	-1.4	0.4	-1.1	-1.6	-1.5	-0.5	-1.3
Severe depression (siblings)	0.6	0.7	4.3	-0.5	0.1	0.0	1.4	1.3	-0.4	-0.0	-0.7	-1.4	0.0	0.1	-0.5	2.1	0.1	-0.2	0.2	0.0	1.5	0.3	0.2	0.1
Pack years adult smoking proportion	0.9	1.4	4.5	-0.8	-0.0	-1.2	2.1	1.9	0.2	-1.5	0.7	-2.1	-1.5	-1.2	-1.3	-0.4	-0.9	-1.6	0.2	-0.6	0.0	-1.4	0.0	-0.8
Impedance of leg (right)	1.1	5.5	12.0	3.0	-2.0	2.8	-1.3	-0.7	-2.0	3.5	-2.6	1.4	2.7	2.7	2.6	1.8	2.8	2.4	2.4	3.2	1.0	2.2	1.6	2.5
Leg fat-free mass (left)	0.5	2.5	6.9	-1.8	-0.1	-1.9	0.9	0.9	2.0	-2.6	1.7	-0.9	-1.1	-1.6	-2.0	-0.4	-2.1	-1.2	-1.3	-2.1	-0.8	-1.2	-1.9	-2.1
Trunk fat percentage	0.2	0.7	5.4	-2.3	-0.2	-0.2	0.8	0.4	1.3	-0.6	0.5	-0.8	0.2	-0.4	-0.4	0.6	-0.7	0.1	1.6	0.0	-0.5	0.1	-0.4	-0.9
Hand grip strength (right)	0.4	1.0	6.1	2.5	-2.1	0.6	-0.2	0.1	-0.5	0.6	-0.7	0.3	1.2	1.0	0.2	1.8	0.8	1.0	-0.5	0.5	1.0	1.0	-0.2	0.4
Townsend deprivation index at recruitment	0.4	0.6	1.8	0.3	1.4	-0.8	-0.1	-1.0	0.2	-1.0	0.9	0.0	-1.2	-1.0	0.2	-1.0	-0.7	-0.4	-1.3	-0.2	-0.7	-1.1	-0.3	-0.5
Current tobacco smoking	0.3	0.5	2.2	0.4	-0.5	0.6	-0.2	-1.5	-0.4	1.4	-1.2	0.2	0.5	0.5	1.3	1.2	0.3	0.5	-0.0	0.7	0.2	0.2	0.5	0.3
Average weekly fortified wine intake	1.4	1.6	6.3	0.7	-0.1	0.9	1.5	0.4	-1.1	1.0	-1.1	-1.5	1.3	1.2	0.8	2.5	1.3	0.7	1.8	1.4	1.5	1.4	1.6	0.9
Maternal smoking around birth	4.5	6.6	10.7	-2.9	2.0	-3.2	3.0	3.3	2.6	-2.3	2.9	-2.8	-2.7	-2.8	-2.1	-0.5	-2.8	-2.7	-0.6	-2.2	-2.1	-2.6	-2.4	-3.1
Fed-up feelings	1.1	2.0	4.8	-0.9	1.9	-1.6	2.0	1.3	1.7	-1.8	0.7	-2.0	-0.7	-1.2	-1.1	-1.1	-1.4	-2.2	0.5	-1.3	-0.9	-1.1	-0.8	-2.0
Frequency of unenthusiasm / disinterest in last 2 weeks	0.6	0.8	2.3	-1.4	1.5	-0.7	1.4	1.4	0.6	-0.4	0.3	-1.5	-0.6	-0.8	-1.2	0.4	-0.5	-1.1	0.1	-0.8	-0.3	-0.5	-0.2	-0.4
Relative age voice broke	1.2	1.8	5.0	1.6	-2.2	1.5	-1.1	-1.3	-1.7	1.0	-1.7	1.0	0.8	1.2	0.6	0.5	1.3	1.3	0.1	1.3	1.7	1.0	1.1	1.9
Taking other prescription medications	6.7	10.3	17.2	-3.9	3.5	-3.6	3.1	2.4	2.6	-2.2	3.3	-3.0	-4.1	-3.8	-3.7	-3.0	-3.4	-4.1	-1.0	-3.7	-2.1	-3.6	-1.7	-3.2
Age when periods started (menarche)	1.3	3.1	13.7	-2.5	1.4	-0.5	3.6	2.8	-0.0	0.2	-0.3	-3.7	-0.6	-0.5	-0.3	1.3	-0.5	-2.0	3.1	-0.7	0.6	-0.5	1.8	-0.2
Bilateral oophorectomy (both ovaries removed)	0.4	0.4	1.0	-0.8	-0.0	-0.5	0.9	0.9	0.2	0.6	0.8	-0.9	-0.9	-0.7	-1.0	-0.6	-0.1	-0.7	0.8	-0.0	-0.3	-0.5	0.2	-0.1
Heel bone mineral density (BMD) T-score, automated (left)	3.7	8.3	13.3	1.8	-2.4	3.6	-2.1	-1.7	-3.1	3.3	-3.4	2.2	3.2	3.3	2.7	2.4	3.5	3.4	2.1	3.3	2.7	2.9	3.0	3.2
Tinnitus: Yes, but not now, but have in the past	1.7	1.8	4.0	0.3	-1.1	1.5	-0.7	-0.0	-1.2	1.2	-1.4	0.7	1.6	1.7	2.0	1.3	1.3	1.7	1.2	1.5	1.4	1.6	1.3	1.4
Qualifications: CSEs or equivalent	0.9	1.2	4.6	-0.1	-1.5	1.0	1.1	1.0	-0.6	-0.5	-1.1	-1.1	1.1	1.0	1.2	1.6	0.9	0.3	2.2	1.3	0.9	0.8	0.9	1.1
Serious illness, injury or assault to yourself	0.9	1.1	3.1	-1.0	1.6	-1.0	0.1	0.0	0.8	-1.8	1.2	-0.0	-1.3	-1.0	-1.2	-1.3	-0.7	-1.1	-1.3	-1.5	-0.3	-0.9	-0.6	-0.5
High blood pressure	7.9	22.0	33.4	-3.0	5.4	-5.6	3.3	4.2	4.3	-4.2	5.2	-3.2	-5.8	-5.5	-5.6	-3.9	-5.0	-5.7	-2.9	-5.5	-4.0	-5.3	-4.0	-4.7
Hayfever, allergic rhinitis or eczema	6.7	14.6	29.6	-5.4	3.9	-4.1	5.4	4.0	4.0	-2.9	3.0	-5.4	-3.5	-3.9	-2.0	-1.7	-4.3	-4.9	2.0	-2.9	-3.8	-3.8	-1.3	-4.2
Multivitamins +/- minerals	0.9	1.1	4.6	-2.1	0.5	-1.0	0.6	0.6	1.0	0.0	1.3	-0.5	-1.2	-1.3	-1.1	-1.0	-0.9	-0.8	0.4	-0.5	-1.7	-1.5	-0.8	-0.8
Stomach or abdominal pain in last month	0.3	0.3	2.1	-0.6	-0.7	0.6	0.0	0.7	-0.1	1.5	-1.1	-0.0	0.3	0.3	0.1	-0.1	0.7	-0.1	0.6	0.1	0.2	0.6	0.4	0.6
Supplements: Glucosamine	0.9	1.2	4.0	-1.9	1.8	-0.6	2.0	1.8	0.6	-0.6	0.3	-2.0	0.2	-0.2	-0.7	0.9	-0.4	-0.8	1.5	-0.2	0.3	-0.5	0.1	-0.8
Diverticular disease/diverticulitis (self-reported)	0.1	0.1	0.2	0.0	0.5	-0.0	0.2	0.5	-0.1	-0.3	0.3	-0.2	-0.0	-0.0	-0.5	0.4	0.2	-0.0	0.1	0.0	0.2	0.1	0.2	0.3
Medication: Atenolol	0.6	0.8	2.2	-0.8	0.9	-0.8	0.7	0.5	0.1	0.6	0.6	-0.8	-1.4	-1.0	-1.2	-1.5	-0.7	-1.3	-0.4	-1.1	-0.7	-0.7	0.0	-0.8
Medication: Levothyroxine sodium	0.1	0.2	1.3	-0.9	0.9	-0.1	0.4	-0.4	0.3	1.1	-0.1	-0.3	-0.1	-0.2	0.1	-0.2	-0.1	-0.4	0.8	-0.5	-0.3	-0.2	0.3	-0.1
Sitting height	0.9	6.6	21.3	1.4	-4.6	2.8	-1.3	-0.4	-2.1	1.4	-3.2	1.3	3.5	3.3	2.5	3.2	2.3	3.0	1.2	2.9	3.1	3.0	0.9	2.3
Chronic bronchitis/emphysema (father)	0.2	0.3	1.9	-1.1	0.2	-0.0	0.6	0.2	0.2	-0.2	-0.4	-0.6	-0.4	-0.2	1.4	-0.0	-0.5	-0.1	0.7	0.6	-0.7	-0.2	0.0	-0.1
High blood pressure (mother)	0.4	0.6	1.2	-0.8	-0.1	-0.7	0.8	0.6	0.8	-0.2	0.6	-0.8	-1.0	-0.8	-0.8	-0.5	-0.8	-1.1	-0.3	-0.9	-0.8	-0.9	-0.4	-0.7
Body mass index (BMI)	2.2	9.2	21.6	-4.7	2.6	-3.2	2.6	2.1	3.6	-4.2	3.6	-2.6	-2.9	-3.4	-3.3	-1.7	-3.4	-2.9	-0.2	-3.2	-2.4	-2.8	-2.2	-3.5
Impedance of leg (left)	1.3	6.5	12.4	3.1	-1.8	3.1	-1.5	-0.9	-2.3	3.5	-2.9	1.5	2.9	2.9	2.8	1.9	3.1	2.5	2.6	3.4	1.3	2.4	2.0	2.9
Leg predicted mass (left)	0.5	2.5	6.7	-1.8	-0.2	-1.9	1.0	0.9	2.0	-2.6	1.7	-1.0	-1.1	-1.6	-2.0	-0.4	-2.1	-1.3	-1.2	-2.1	-0.8	-1.3	-1.9	-2.1
Trunk fat mass	0.3	1.4	6.2	-2.5	-0.1	-0.9	1.1	1.0	1.9	-1.5	1.2	-1.1	-0.3	-1.0	-1.1	0.4	-1.3	-0.5	0.8	-0.8	-0.9	-0.5	-1.2	-1.6
Waist circumference	1.0	3.8	9.2	-2.3	1.5	-2.0	0.5	0.5	2.7	-3.0	2.5	-0.5	-1.8	-2.3	-2.4	-1.4	-2.2	-1.3	-0.8	-2.1	-2.0	-1.8	-2.1	-2.3
Number of incorrect matches in round	0.2	0.4	1.5	0.0	0.7	-0.6	-0.0	-0.2	0.5	0.5	0.7	0.1	-1.2	-1.1	-0.3	-1.0	-0.4	-0.3	-0.2	-0.0	-0.9	-0.7	0.1	-0.3
Past tobacco smoking	0.3	0.5	2.8	0.9	-0.7	0.3	-0.7	-1.7	-0.4	0.4	-0.1	0.6	-0.2	0.1	1.4	0.9	-0.1	0.9	-0.9	0.8	-0.0	-0.1	0.1	0.5
Alcohol usually taken with meals	0.3	0.5	1.7	-0.1	0.1	-0.2	-1.1	-0.8	0.5	-1.0	0.8	1.1	-0.1	-0.2	-0.5	-1.3	-0.2	0.0	-0.9	-0.6	-1.0	-0.0	-0.4	-0.5
Nervous feelings	0.7	1.4	3.6	1.2	-0.3	0.9	-1.7	-1.6	-1.9	0.1	-0.4	1.7	0.3	0.7	-0.1	0.2	1.2	1.3	-1.8	0.3	1.9	0.9	0.7	1.6
Frequency of tenseness / restlessness in last 2 weeks	0.2	0.2	0.9	0.2	0.2	0.5	-0.8	0.3	-0.7	0.0	-0.4	0.7	-0.4	-0.1	-0.6	-0.7	0.7	0.2	-0.3	0.0	0.3	0.2	0.3	1.0
Hearing difficulty/problems with background noise	0.9	1.4	4.9	-0.0	0.0	0.3	2.2	2.1	-1.1	-0.1	-1.0	-2.2	0.6	0.7	0.5	1.1	0.8	-0.5	1.9	0.8	1.6	0.7	1.6	0.4
Hair/balding pattern: Pattern 2	0.6	0.7	2.5	-0.2	-0.2	0.6	1.1	0.9	-1.1	1.0	-0.2	-1.1	0.7	0.7	0.8	0.3	0.7	0.3	1.6	1.1	0.8	0.9	1.2	0.5
Had menopause	1.6	1.9	4.7	-1.2	1.8	-1.6	0.4	0.1	1.9	-0.5	2.0	-0.5	-1.2	-1.7	-1.0	-1.6	-1.7	-1.2	-0.5	-1.4	-2.2	-1.1	-1.3	-1.8
Had other major operations	1.2	1.4	3.9	-1.8	2.0	-1.2	0.8	1.3	1.1	-1.5	1.3	-0.8	-1.1	-1.1	-1.0	-1.4	-0.9	-1.3	0.4	-1.0	-1.6	-1.1	-0.5	-0.9
Forced vital capacity (FVC)	0.7	2.7	7.7	1.2	-2.3	1.6	-0.1	-0.1	-1.0	1.6	-1.8	0.2	2.1	1.9	2.0	2.8	1.5	2.0	1.6	2.4	1.5	1.4	1.0	1.6
Heel bone mineral density (BMD) T-score, automated (right)	1.4	3.2	5.6	0.6	-1.0	2.4	-0.8	-0.6	-1.8	2.2	-2.0	0.9	2.3	2.1	1.3	2.2	2.3	2.2	1.8	2.0	1.7	2.0	1.8	2.0
Ever unenthusiastic/disinterested for a whole week	0.2	0.3	1.3	-0.9	-0.1	0.0	0.1	-0.5	-0.3	-0.1	0.7	-0.1	-0.5	-0.3	-0.3	-1.1	0.2	-0.2	1.0	0.2	-0.3	-0.2	0.8	0.2
Qualifications: None of the above	1.1	2.5	10.2	-1.8	0.1	-1.6	0.4	-0.1	1.1	-0.2	1.9	-0.4	-2.2	-2.0	-2.1	-3.2	-1.4	-1.9	-0.2	-1.8	-1.7	-1.9	-0.8	-1.2
Financial difficulties in last 2 years	0.4	0.6	2.6	-0.4	-1.6	0.7	-0.1	0.7	-0.8	0.1	-0.5	0.1	0.7	0.8	0.4	1.1	0.9	0.7	0.9	0.8	1.0	1.0	0.5	0.8
Mouth/teeth dental problems	1.7	2.7	7.8	1.7	-1.2	1.2	-2.5	-1.6	-1.4	0.3	-0.8	2.5	1.3	1.5	1.6	2.2	1.0	2.8	-2.4	1.5	1.2	1.0	-0.6	1.2
Heart attack	0.5	0.6	4.5	-0.4	-0.6	0.7	0.2	0.4	-0.2	0.9	-1.1	-0.2	1.2	0.8	0.5	0.1	0.7	-0.1	2.1	0.6	0.1	0.9	0.6	0.2
Allergy	7.6	17.5	29.5	5.4	-4.1	4.8	-5.3	-3.9	-4.3	3.6	-3.7	5.3	4.2	4.5	2.7	2.3	4.9	5.3	-1.0	3.5	4.2	4.5	2.0	5.0
Pain all over the body in last month	0.3	0.4	2.1	0.2	-0.2	0.1	-0.4	-0.7	-1.0	-0.8	0.4	0.3	-0.6	-0.1	0.1	-0.5	0.2	0.0	-1.4	-0.3	1.1	0.1	0.6	0.6
Diabetes (self-reported)	3.6	5.5	11.2	-2.1	2.4	-2.9	1.9	1.1	1.6	-2.3	2.7	-2.0	-3.4	-3.0	-2.5	-2.6	-2.5	-3.1	-1.2	-2.7	-1.7	-2.9	-0.9	-2.2
Hayfever/allergic rhinitis (self-reported)	3.6	4.8	9.4	-2.7	2.1	-2.5	2.1	0.9	2.7	-1.4	2.2	-2.1	-2.2	-2.6	-1.7	-1.5	-2.7	-2.4	0.5	-1.9	-3.1	-2.4	-1.4	-3.0
Medication: Ramipril	7.3	9.4	19.6	-3.1	4.4	-3.3	2.6	2.5	3.2	-3.3	3.2	-2.5	-2.9	-3.1	-3.4	-3.3	-2.9	-4.0	-0.1	-3.4	-3.1	-2.6	-1.8	-3.2
Medication: Simvastatin	1.0	1.5	5.4	-0.9	2.3	-1.3	1.5	0.5	0.2	-1.5	1.4	-1.5	-1.9	-1.5	-1.3	-0.1	-0.9	-1.3	-0.8	-1.1	-0.1	-1.4	-0.0	-0.5
Fluid intelligence score	1.9	4.0	7.7	1.3	0.1	2.1	0.8	0.8	-2.0	2.0	-2.5	-0.8	2.1	2.4	2.3	2.2	2.4	1.2	2.6	2.5	1.8	2.4	2.8	2.2
Illnesses of siblings	2.0	2.8	6.6	1.7	-1.3	2.1	-2.3	-2.6	-1.3	1.0	-1.3	2.1	1.9	1.7	1.7	0.8	1.5	2.5	0.4	1.6	1.1	1.5	1.2	1.5
Neuroticism score	0.3	0.7	2.8	-1.1	1.7	-0.1	1.0	0.7	-0.9	-0.5	-0.1	-1.1	-0.1	0.0	-0.7	-0.7	0.6	-0.9	0.6	-0.3	1.2	0.5	1.4	0.2
Weight	0.7	3.3	8.4	-2.6	0.4	-1.9	1.4	1.4	2.6	-2.9	2.0	-1.4	-1.1	-1.8	-2.2	-0.4	-2.2	-1.4	-0.2	-2.0	-1.3	-1.4	-2.0	-2.4
Impedance of arm (right)	6.1	28.6	41.9	5.4	-5.7	6.4	-5.0	-4.2	-5.7	6.1	-6.3	5.0	5.5	5.9	6.1	2.9	5.6	6.4	1.9	6.5	3.9	5.5	3.5	6.0
Arm fat percentage (right)	0.5	2.0	9.2	-3.0	0.6	-1.1	0.4	0.4	1.9	-2.1	1.7	-0.4	-1.2	-1.6	-1.4	-1.1	-1.7	-0.6	0.3	-1.1	-1.5	-1.1	-1.3	-1.5
Trunk fat-free mass	0.7	3.8	7.2	-1.5	0.3	-2.4	1.8	2.2	2.4	-2.6	2.0	-1.8	-1.3	-1.8	-2.2	-0.4	-2.3	-2.2	-1.1	-2.7	-1.1	-1.6	-2.1	-2.5
Hip circumference	0.6	2.4	9.1	-2.3	0.2	-1.5	0.9	1.2	2.4	-3.0	1.6	-0.9	-0.7	-1.5	-1.8	-0.4	-1.8	-1.0	-0.0	-1.6	-1.1	-1.0	-1.7	-1.9
Time employed in main current job	0.5	0.5	2.5	0.0	-0.1	0.7	-1.2	-1.6	-0.2	0.8	-0.9	1.1	1.0	0.8	0.6	-0.4	0.6	0.7	0.1	0.2	0.1	0.8	0.6	0.3
Alcohol intake versus 10 years previously	0.8	1.2	2.8	-1.5	1.5	-0.7	1.0	1.4	1.1	-1.5	0.5	-0.9	-0.3	-0.8	-0.8	-1.7	-0.7	-1.4	1.6	-0.7	-1.5	-0.4	0.1	-1.1
Father’s age at death	0.3	0.5	2.7	-0.0	1.7	-0.6	0.2	-0.5	1.0	0.4	0.3	-0.3	0.0	-0.4	-0.4	-0.6	-0.7	-0.6	-0.4	-0.9	-1.0	-0.1	-0.7	-0.9
Worrier / anxious feelings	0.6	1.1	5.0	0.5	0.5	0.9	0.2	-0.2	-2.1	0.2	-0.6	-0.3	0.2	0.7	-0.1	-1.2	1.4	-0.2	1.0	0.6	2.1	1.0	2.2	1.4
Frequency of tiredness / lethargy in last 2 weeks	1.9	3.1	9.4	-2.3	1.7	-1.8	1.4	1.8	0.9	-3.1	1.5	-1.4	-2.0	-1.8	-2.4	-1.2	-1.4	-2.4	-1.1	-2.2	-0.5	-1.7	-1.0	-1.1
Falls in the last year	0.6	0.8	4.1	-0.0	-0.1	-0.6	-1.0	-0.6	0.3	-0.3	0.5	1.0	-1.4	-1.1	-0.6	-1.7	-0.7	-0.4	-2.0	-1.0	-0.4	-0.7	-0.6	-0.5
Hair/balding pattern: Pattern 3	0.3	0.5	4.3	2.1	-0.3	-0.2	-0.6	-0.3	0.3	-0.7	0.0	0.6	-0.1	-0.1	0.0	-1.2	0.1	-0.3	-1.4	-0.2	-0.3	0.0	-0.5	-0.2
Number of live births	5.3	7.5	17.4	-3.0	2.4	-3.0	4.1	3.4	1.7	-2.3	2.4	-4.2	-3.3	-3.0	-2.3	-1.8	-2.7	-3.9	0.9	-2.3	-1.6	-2.9	-0.5	-2.5
Forced expiratory volume in 1-second (FEV1)	0.4	1.4	4.5	0.7	-1.5	1.0	0.4	0.4	-0.2	0.8	-1.2	-0.4	1.7	1.3	1.6	2.1	0.9	1.2	1.9	1.7	0.7	0.9	0.8	0.7
Pulse rate	0.9	1.5	3.5	0.2	0.3	-1.3	1.8	1.3	0.5	-1.7	1.1	-1.8	-1.7	-1.5	-1.1	-0.9	-1.3	-1.9	-0.5	-1.0	-0.4	-1.7	-0.2	-1.0
Happiness	0.7	0.9	4.6	-1.4	1.4	-0.4	1.4	2.1	0.6	-0.3	0.2	-1.6	0.2	-0.1	-1.1	0.6	-0.2	-1.1	0.9	-0.9	0.0	0.3	-0.2	-0.7
Noisy workplace	0.1	0.2	1.3	-0.2	-1.1	0.1	0.5	0.1	0.2	-0.5	-0.3	-0.5	0.1	-0.1	-0.4	0.8	0.1	-0.2	0.5	-0.2	0.3	-0.0	0.1	-0.1
Qualifications: A levels/AS levels or equivalent	0.9	1.9	3.8	1.9	-0.8	1.3	-0.3	-0.2	-1.7	1.7	-1.5	0.3	1.4	1.6	1.7	1.6	1.5	1.4	0.3	1.7	1.4	1.7	1.4	1.4
Serious illness, injury or assault of a close relative in last 2 years	0.3	0.3	1.0	0.0	-0.4	0.6	-0.4	0.2	-0.8	-0.0	-0.6	0.4	0.7	0.7	0.3	-0.3	0.9	0.3	0.5	0.4	0.7	1.0	0.8	0.6
Mouth/teeth dental problems: Dentures	0.4	0.7	4.5	-0.7	0.0	-0.4	1.4	0.7	0.7	0.9	-0.2	-1.3	-0.1	-0.3	0.2	-0.8	-0.5	-1.0	2.1	-0.2	-0.7	0.2	0.9	-0.6
Asthma	3.3	6.4	9.6	-3.0	2.3	-3.0	2.5	2.0	2.8	-2.2	2.4	-2.5	-2.6	-2.8	-2.1	-1.8	-3.0	-3.1	-0.0	-2.4	-2.8	-3.0	-1.8	-3.1
Medication: Ibuprofen (e.g. Nurofen)	2.8	3.5	7.6	-2.2	1.1	-2.1	1.0	0.5	2.7	-1.8	1.9	-1.0	-1.8	-2.1	-1.8	-1.4	-2.1	-2.2	-0.5	-2.2	-2.0	-2.3	-2.0	-2.3
Medication: Cholesterol lowering	1.5	2.3	6.5	-1.9	2.5	-1.7	1.5	1.0	0.8	-0.2	1.2	-1.4	-2.0	-1.7	-1.9	-1.2	-1.4	-2.2	-0.7	-1.9	-1.1	-1.6	-0.3	-1.4
Depression (self-reported)	0.4	0.5	2.4	-0.2	1.0	-0.6	-0.1	-0.5	0.1	-1.0	1.1	0.2	-0.7	-0.8	-1.5	-0.3	-0.1	-0.2	-1.4	-1.1	0.5	-0.3	-0.4	-0.1
Medication: Lansoprazole	0.4	0.4	2.4	0.5	0.5	-0.0	1.1	0.7	-0.4	-0.7	0.0	-1.1	-0.1	-0.1	-0.2	-0.7	0.4	-0.9	1.6	0.2	0.0	-0.2	1.0	0.2
Prospective memory result	0.5	0.6	2.7	-1.7	0.7	-0.5	-0.6	-1.0	0.7	-1.2	0.7	0.6	-0.3	-0.5	-0.3	-1.2	-0.8	-0.2	-0.8	-0.9	-0.3	-0.4	-0.5	-0.6
Lung cancer (father)	1.3	1.5	7.0	-2.7	0.0	-1.1	1.8	1.9	1.3	0.3	0.6	-1.7	-0.9	-1.1	-0.4	-0.3	-1.3	-1.3	0.8	-1.0	-1.1	-0.6	-0.4	-1.4
Illnesses of mother	0.2	0.3	2.1	-0.5	0.8	0.2	0.5	0.7	0.0	0.2	-0.3	-0.5	0.7	0.4	0.5	1.5	0.4	0.4	0.4	0.5	0.7	0.4	0.2	0.0
Forced expiratory volume in 1-second (FEV1), Best measure	0.3	0.8	3.5	0.2	-0.8	0.7	0.4	0.7	0.2	-0.2	-0.8	-0.4	1.5	1.0	1.2	1.6	0.7	0.9	1.9	1.2	0.2	0.9	0.5	0.4
Pulse wave Arterial Stiffness index	1.4	1.7	3.5	-0.3	0.9	-1.5	1.1	0.6	1.3	-0.9	1.6	-1.1	-1.9	-1.9	-1.5	-0.6	-1.5	-1.3	-0.9	-1.4	-1.0	-1.7	-1.3	-1.4
Impedance of arm (left)	6.6	30.3	45.6	5.5	-5.9	6.5	-5.5	-4.9	-5.7	6.3	-6.3	5.4	5.7	6.0	6.1	2.9	5.8	6.8	1.7	6.6	3.8	5.7	3.6	6.0
Arm fat mass (right)	0.7	3.1	9.1	-3.0	0.6	-1.7	1.1	1.1	2.5	-2.7	2.1	-1.2	-1.3	-1.9	-1.9	-0.9	-2.1	-1.2	0.2	-1.7	-1.5	-1.3	-1.6	-2.2
Trunk predicted mass	0.6	3.6	7.0	-1.5	0.3	-2.4	1.8	2.2	2.4	-2.6	1.9	-1.8	-1.2	-1.7	-2.2	-0.3	-2.2	-2.1	-1.1	-2.6	-1.0	-1.5	-2.2	-2.5
Standing height	0.7	6.5	22.1	3.9	-4.7	2.5	-2.0	-1.2	-1.8	2.4	-3.0	2.0	3.4	3.0	2.1	2.4	2.4	2.7	0.1	2.1	2.1	2.8	0.4	2.0
Length of working week for main job	0.3	0.3	0.9	0.4	-0.0	0.6	-0.2	0.6	-0.9	-0.2	-0.4	0.3	0.2	0.5	0.2	0.3	0.9	0.5	0.2	0.7	0.5	0.6	0.8	0.8
Exposure to tobacco smoke at home	0.5	0.5	1.2	-0.1	0.2	-0.9	0.7	1.1	1.1	-0.6	0.6	-0.7	-0.3	-0.5	-0.6	-0.4	-0.8	-0.9	0.5	-0.6	-0.8	-0.8	-0.6	-1.0
Breastfed as a baby	0.1	0.1	0.4	0.2	0.6	-0.4	0.2	-0.1	0.3	-0.1	0.4	-0.2	-0.3	-0.4	-0.1	0.4	-0.4	-0.3	0.2	-0.3	-0.2	-0.2	-0.3	-0.1
Tense / ‘highly strung’	1.7	2.8	10.8	1.1	-1.0	1.8	-0.5	-0.0	-2.9	0.2	-1.6	0.5	1.0	1.7	0.9	1.3	2.4	1.3	-0.2	1.5	3.3	1.9	2.2	2.5
Seen doctor (GP) for nerves, anxiety, tension or depression	0.6	0.9	2.7	-1.7	0.5	-0.8	1.2	0.8	-0.4	-0.2	1.0	-1.2	-1.3	-0.9	-1.6	-0.2	-0.5	-1.2	-0.6	-1.1	0.8	-1.0	0.3	-0.0
Hair/balding pattern: Pattern 4	1.7	4.2	8.2	1.8	-2.1	2.4	-1.7	-1.7	-2.0	1.7	-2.9	1.7	2.5	2.5	1.8	2.4	2.3	2.1	0.2	1.8	2.3	2.1	1.8	2.0
Birth weight of first child	0.8	1.5	5.0	0.3	-2.2	1.2	-1.0	-1.2	-1.1	0.7	-1.1	1.1	1.6	1.4	-0.0	2.0	1.1	1.3	-0.9	0.3	1.7	1.5	0.1	0.8
Peak expiratory flow (PEF)	0.8	1.8	6.2	-1.1	0.5	-1.5	1.8	2.5	1.5	-1.9	1.1	-1.9	-0.5	-0.9	-1.3	0.2	-1.1	-1.6	0.1	-1.3	-0.7	-1.1	-0.9	-1.7
Pulse wave reflection index	0.2	0.2	0.8	-0.1	0.3	-0.6	0.5	-0.1	0.2	0.3	0.5	-0.5	-0.9	-0.8	-0.4	-0.5	-0.4	-0.4	-0.3	-0.3	-0.5	-0.5	0.1	-0.5
Ever highly irritable/argumentative for 2 days	1.0	1.2	4.1	0.0	-1.3	0.7	1.4	1.4	-1.0	0.7	-0.8	-1.4	1.0	1.0	0.2	0.9	1.0	0.0	2.0	0.9	1.2	1.5	1.5	0.6
Loud music exposure frequency	0.1	0.1	0.6	0.8	-0.2	0.3	-0.6	-0.6	-0.1	0.6	0.0	0.6	0.3	0.3	-0.1	0.2	0.2	0.5	-0.3	0.1	0.1	0.4	0.2	0.2
Qualifications: O levels/GCSEs or equivalent	0.8	1.3	3.5	1.0	-0.3	1.1	-0.3	-0.8	-0.8	1.3	-0.7	0.3	1.1	1.2	1.9	1.7	1.1	1.5	1.0	1.7	0.8	1.2	1.0	1.2
Mouth/teeth dental problems: Bleeding gums	1.0	1.2	4.1	-0.2	0.1	-0.7	-1.1	-0.5	1.3	-1.4	0.6	1.1	-0.5	-0.9	-1.6	-2.0	-0.8	-0.9	-1.3	-1.6	-1.0	-1.0	-1.6	-1.0
Blood clot in the leg (DVT)	0.3	0.4	1.2	-1.1	0.1	0.8	0.0	0.2	-1.0	0.2	-1.0	-0.0	0.5	0.7	0.8	0.3	0.6	0.4	0.7	0.9	0.8	0.8	0.8	0.6
Medication: Paracetamol	3.3	5.5	9.2	-2.0	1.7	-2.8	1.5	0.7	2.1	-2.9	3.0	-1.5	-2.9	-2.8	-2.6	-2.4	-2.4	-2.8	-1.5	-3.0	-1.8	-2.6	-1.7	-2.4
Headache pain in last month	4.7	8.1	15.6	-2.7	2.3	-3.2	2.4	1.1	2.7	-3.4	3.3	-2.4	-3.5	-3.4	-2.8	-2.9	-3.0	-4.0	-0.7	-3.6	-2.6	-3.5	-1.5	-2.5
Medication for cholesterol, blood pressure or diabetes	6.5	10.8	18.1	2.9	-4.1	4.1	-2.9	-2.3	-2.7	2.5	-3.7	2.9	4.0	3.7	3.6	2.1	3.6	4.3	2.1	4.0	2.4	3.7	2.2	3.5
Glaucoma (self-reported)	0.2	0.3	1.1	0.3	0.3	0.0	-0.3	0.1	-0.2	-0.9	0.2	0.4	-0.0	0.1	-1.1	-0.6	0.2	-0.3	-1.0	-0.9	1.0	0.4	-0.0	0.1
Gout (self-reported)	3.0	4.1	8.4	-2.7	2.4	-2.0	2.5	2.4	2.9	-0.4	1.1	-2.5	-1.4	-1.8	-1.6	-0.2	-2.2	-2.5	0.7	-1.7	-2.5	-1.9	-1.8	-2.4
Hypothyroidism/myxoedema (self-reported)	0.4	0.8	2.7	-1.6	1.3	-0.6	0.9	0.3	0.7	1.4	-0.0	-0.9	-0.8	-0.8	-0.3	-1.0	-0.7	-1.4	0.9	-1.0	-0.9	-1.0	0.2	-0.6
Medication: Amlodipine	4.2	5.9	8.9	-2.1	2.8	-2.9	2.5	2.0	2.2	-1.7	2.8	-2.4	-3.0	-2.9	-2.8	-1.5	-2.8	-3.0	-1.0	-2.6	-1.8	-2.9	-1.6	-2.6
Medication: Ventolin 100micrograms inhaler	1.0	1.3	6.4	-0.9	-0.4	-1.0	2.5	1.1	0.2	-1.5	0.8	-2.5	-0.3	-0.3	-0.9	1.7	-0.7	-1.1	0.0	-0.6	1.2	-0.6	-0.1	-1.0
Birth weight	2.1	4.5	15.8	1.6	-4.0	2.2	-2.3	-1.6	-2.3	1.0	-2.0	2.3	2.0	2.3	1.1	2.2	2.2	2.5	-1.3	1.6	2.6	2.2	0.2	2.1
Chronic bronchitis/emphysema (mother)	1.6	1.9	4.4	-0.8	1.8	-1.6	0.8	0.7	1.2	-1.5	2.1	-0.7	-1.4	-1.6	-1.7	-1.5	-1.2	-1.2	-0.3	-1.3	-1.8	-1.3	-1.2	-1.6
High blood pressure (siblings)	2.1	3.0	7.3	-1.2	0.2	-2.2	0.9	1.4	1.4	-0.7	1.7	-0.8	-2.3	-2.1	-2.7	-0.7	-1.9	-1.8	-2.1	-2.0	-1.3	-2.1	-2.4	-1.7
Forced vital capacity (FVC), Best measure	0.3	1.2	3.6	0.3	-1.3	1.1	-0.2	0.3	-0.4	0.1	-1.1	0.3	1.6	1.3	1.3	1.9	1.0	1.5	1.5	1.6	0.8	1.0	0.6	1.1
Body fat percentage	0.4	1.7	9.1	-3.0	0.6	-1.0	0.9	0.8	2.1	-1.6	1.5	-0.9	-0.6	-1.3	-1.4	-0.2	-1.4	-0.5	1.1	-0.8	-1.3	-0.7	-1.2	-1.6
Leg fat percentage (right)	1.6	5.7	13.6	-3.7	1.8	-2.4	1.8	2.0	3.2	-2.6	3.0	-1.8	-2.0	-2.6	-2.9	-1.3	-2.5	-2.0	0.6	-2.2	-2.4	-2.2	-2.2	-2.8
Arm fat-free mass (right)	1.5	7.6	12.6	-2.9	1.6	-3.3	2.9	2.7	3.6	-3.5	3.0	-2.9	-1.9	-2.7	-3.3	-0.4	-3.0	-3.1	-0.7	-3.5	-1.8	-2.2	-2.5	-3.5
Exposure to tobacco smoke outside home	0.6	0.7	3.1	-0.6	-1.1	0.7	-0.0	-0.3	-0.5	0.6	-1.2	0.0	1.0	1.1	1.8	1.4	0.6	0.6	0.6	0.6	0.9	1.1	0.6	0.5
Comparative body size at age 10	0.3	1.0	3.6	-1.9	0.8	-0.5	-0.0	0.7	1.1	-1.9	1.2	0.0	-0.1	-0.5	-1.7	0.8	-0.5	-0.0	-0.9	-1.0	0.0	-0.3	-1.6	-0.6
Number of full brothers	1.2	1.5	5.3	-1.4	1.1	-1.2	2.3	2.0	0.4	-1.1	0.5	-2.3	-1.4	-1.1	-0.9	-0.4	-0.9	-1.9	-0.0	-1.0	0.1	-1.0	-0.1	-1.1
Worry too long after embarrassment	0.2	0.3	2.7	-0.4	1.7	-0.5	0.4	-0.3	0.2	-0.4	0.4	-0.6	-0.4	-0.3	-0.4	-0.7	-0.3	-0.8	-0.2	-0.5	-0.1	-0.3	0.0	-0.5
Seen a psychiatrist for nerves, anxiety, tension or depression	0.3	0.4	1.9	1.3	-0.3	0.3	-0.5	-0.5	-0.9	-0.2	-0.1	0.4	-0.1	0.1	0.1	0.4	0.5	0.5	-1.4	0.2	1.0	0.1	0.2	0.8
Wheeze or whistling in the chest in last year	3.4	6.0	10.1	-2.8	3.1	-2.7	2.3	2.5	2.8	-3.2	2.6	-2.3	-2.2	-2.5	-2.7	-0.4	-2.5	-2.6	-0.5	-2.6	-1.9	-2.5	-2.0	-2.4
Number of children fathered	0.9	1.1	4.8	-0.4	-0.5	-0.1	2.1	2.2	-0.1	0.1	-0.3	-2.1	0.5	0.3	-0.2	0.8	0.4	-1.1	2.1	-0.1	0.6	0.4	0.6	-0.1
Reason for reducing amount of alcohol drunk: Health precaution	6.0	7.1	13.6	2.2	-1.8	3.2	-3.2	-3.3	-2.6	3.2	-2.4	3.2	2.7	2.8	1.8	1.5	3.1	3.7	0.7	2.8	2.1	2.6	1.8	3.0
Age at first live birth	1.1	2.0	4.9	1.9	-0.8	1.6	-2.1	-1.3	-1.6	0.4	-0.8	2.1	1.3	1.3	1.3	0.3	1.6	2.2	-0.3	1.4	1.2	1.3	1.1	1.7
Pulse wave peak to peak time	1.7	1.9	4.4	0.3	-1.0	1.6	-1.1	-0.5	-1.4	1.0	-1.8	1.1	2.1	2.0	1.6	0.8	1.6	1.4	1.1	1.5	1.1	1.8	1.3	1.5
Health satisfaction	2.1	2.7	6.4	-1.1	0.8	-1.8	1.7	2.0	0.9	-2.5	1.7	-1.8	-1.7	-1.7	-2.4	-0.4	-1.3	-2.0	-1.7	-2.2	-0.0	-1.2	-1.4	-1.6
Shortness of breath walking on level ground	0.9	1.1	4.5	-0.2	-1.0	-0.0	2.1	1.8	-0.5	-0.9	-0.6	-2.1	0.0	0.3	0.2	1.9	0.3	-0.6	0.6	0.2	1.7	0.5	0.6	0.3
Qualifications: College or University degree	0.3	1.0	3.2	1.8	0.9	0.4	-0.6	-0.4	-0.7	1.7	-1.0	0.6	1.2	1.0	1.1	1.5	0.6	1.0	-1.2	0.7	0.6	0.9	-0.0	0.3
Eye problems/disorders: None of the above	2.8	3.2	5.5	2.2	-1.9	2.0	-0.3	-0.6	-1.7	1.7	-2.4	0.3	1.9	2.0	2.1	0.9	2.1	1.3	2.3	2.2	1.2	1.9	2.2	1.8
Mouth/teeth dental problems: Loose teeth	1.4	1.7	3.6	1.2	-1.9	1.3	-0.1	-0.3	-1.3	1.9	-1.4	0.0	1.0	1.2	1.3	1.7	1.3	1.3	1.4	1.6	1.4	1.1	1.4	1.4
Emphysema/chronic bronchitis	0.8	0.9	1.6	-0.2	0.8	-1.3	0.9	0.4	0.8	-1.2	1.2	-0.8	-1.0	-1.1	-1.2	-0.5	-1.0	-1.0	-0.8	-1.0	-0.6	-0.9	-1.0	-1.2
Medication for pain relief, constipation, heartburn	6.2	10.6	16.7	3.6	-3.1	3.9	-3.0	-2.6	-2.8	3.0	-3.6	3.0	4.0	4.0	3.8	2.2	3.3	4.1	1.4	3.8	2.2	3.8	2.3	3.3
Neck or shoulder pain in last month	1.8	2.5	12.3	-1.6	-0.4	1.4	1.8	1.1	-1.4	-0.2	-1.3	-1.8	1.3	1.3	-0.0	1.3	1.6	-0.4	3.5	0.7	2.2	1.5	2.5	1.5
Medication: Blood pressure	8.4	14.9	25.0	-2.8	3.9	-4.8	3.2	2.6	3.6	-3.2	4.4	-3.1	-4.4	-4.4	-4.5	-2.7	-4.3	-5.0	-2.6	-4.9	-2.9	-4.2	-3.3	-4.4
Angina (self-reported)	0.4	0.6	2.6	0.5	0.1	-0.8	1.0	1.6	0.8	0.0	0.2	-1.0	-0.3	-0.5	-1.1	-0.1	-0.7	-1.0	0.5	-0.5	-0.7	-0.5	-0.9	-1.0
Migraine (self-reported)	3.2	4.0	9.4	-1.9	1.6	-1.9	0.4	0.1	1.7	-2.1	1.6	-0.4	-2.6	-2.4	-2.5	-3.1	-2.1	-2.5	-1.6	-2.8	-1.7	-2.3	-1.5	-1.9
Medication: Ibuprofen	3.2	3.8	8.0	-2.8	1.9	-2.2	1.8	1.4	2.5	-2.0	1.7	-1.8	-1.7	-2.1	-1.7	-1.7	-2.0	-2.6	0.4	-2.1	-1.9	-2.0	-1.4	-2.3
Medication: Allopurinol	2.1	2.8	6.0	-1.9	1.7	-1.8	1.7	1.4	2.5	-0.8	1.5	-1.7	-1.4	-1.7	-1.8	-0.4	-1.9	-2.0	0.0	-1.8	-1.8	-1.7	-1.6	-2.0
Medication: Omeprazole	2.2	2.6	5.2	-1.4	1.6	-1.6	-0.1	0.4	1.3	-2.3	2.0	0.0	-1.7	-1.7	-2.3	-2.2	-1.7	-1.3	-1.6	-1.9	-1.3	-1.9	-1.8	-1.3
Medication: Seretide 50 evohaler	0.3	0.3	1.8	0.2	-1.2	0.2	-0.3	-0.6	0.3	0.0	-0.3	0.3	0.9	0.7	0.3	1.3	-0.0	0.5	-0.1	0.3	0.5	0.2	-0.7	0.0
Mean time to correctly identify matches	0.9	1.7	4.4	0.6	-1.4	1.4	-1.8	-1.9	-1.6	2.1	-0.9	1.7	0.3	0.7	1.5	-0.8	1.0	1.4	0.0	1.0	0.9	1.1	1.7	1.5
Heart disease (mother)	0.3	0.3	3.8	0.9	-2.0	-0.0	0.2	-0.6	-0.2	1.1	-0.1	-0.3	0.2	0.1	-0.2	0.2	0.4	0.2	0.1	0.3	0.6	0.2	-0.2	-0.1
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.0	1.2	5.0	-0.1	0.6	0.8	0.7	-0.3	-0.4	2.2	-1.5	-0.6	1.3	1.1	2.1	0.3	0.8	-0.2	2.0	0.7	0.1	1.1	1.7	0.5
Whole body fat mass	0.6	2.6	8.6	-2.9	0.6	-1.6	1.3	1.2	2.5	-2.3	1.9	-1.3	-0.9	-1.6	-1.8	-0.2	-1.9	-1.0	0.5	-1.4	-1.4	-1.1	-1.7	-2.1
Leg fat mass (right)	1.6	6.3	13.4	-3.7	1.5	-2.6	1.9	1.9	3.4	-3.4	3.1	-1.9	-2.1	-2.8	-3.1	-1.0	-2.8	-2.1	0.0	-2.5	-2.2	-2.3	-2.4	-3.0
Arm predicted mass (right)	1.4	7.3	12.4	-2.9	1.6	-3.2	3.1	2.9	3.5	-3.2	2.8	-3.1	-1.7	-2.5	-3.1	-0.2	-2.9	-3.1	-0.4	-3.4	-1.6	-2.1	-2.4	-3.5
Pulse rate, automated reading	0.8	2.5	4.8	-0.7	1.9	-1.9	1.5	1.2	2.0	-1.6	1.7	-1.4	-1.5	-1.7	-1.4	-0.3	-2.2	-1.8	-0.9	-1.8	-1.4	-1.9	-1.5	-1.9
Alcohol intake frequency.	3.8	8.9	17.8	-4.2	3.3	-2.7	3.9	3.7	2.5	-3.2	2.4	-3.9	-3.2	-3.3	-2.5	-2.6	-2.6	-4.0	1.9	-2.4	-2.5	-2.9	-0.3	-2.3
Comparative height size at age 10	1.0	5.6	14.1	3.8	-3.4	2.2	-2.7	-2.5	-1.8	3.0	-2.0	2.7	2.4	2.4	2.3	1.4	2.0	3.0	-1.3	2.2	1.6	2.4	0.4	1.9
Number of full sisters	0.6	0.7	2.8	-1.4	-0.1	-0.6	1.7	1.1	0.5	0.0	0.2	-1.6	-0.4	-0.5	-0.3	0.2	-0.5	-1.0	1.5	-0.1	-0.3	-0.5	0.4	-0.8
Suffer from ‘nerves’	0.2	0.3	1.0	-0.6	0.3	0.1	1.0	0.8	-0.6	0.1	0.1	-1.0	-0.4	-0.1	-0.3	0.8	0.3	-0.1	0.4	0.4	0.8	0.1	0.8	0.6
Overall health rating	4.6	10.0	18.3	-3.4	2.3	-3.4	1.3	1.1	3.2	-3.7	3.1	-1.3	-3.9	-3.9	-3.9	-3.0	-3.5	-3.6	-2.6	-4.3	-2.7	-3.6	-2.8	-3.1
Chest pain or discomfort	1.2	1.8	4.2	-0.7	0.7	-1.6	1.4	1.3	1.5	-1.5	1.1	-1.4	-1.2	-1.4	-2.0	-0.6	-1.4	-1.8	-0.6	-1.4	-1.0	-1.4	-1.2	-1.7
Had major operations	2.1	2.4	5.1	-1.5	2.3	-2.0	2.1	1.1	1.5	-0.1	1.7	-2.1	-1.6	-1.7	-0.5	-1.1	-1.6	-2.1	0.6	-1.1	-1.7	-1.5	-0.4	-1.9
Age at last live birth	0.8	1.1	2.4	1.6	-1.4	1.0	-1.3	-1.3	-1.2	-0.7	-0.6	1.3	0.7	0.8	1.3	-0.3	0.9	1.3	-0.7	0.8	1.2	0.7	1.0	1.0
Family relationship satisfaction	0.6	0.7	3.9	-0.7	0.2	0.1	1.5	1.8	-0.1	0.2	-0.6	-1.7	0.3	0.1	0.1	-0.1	0.3	-0.9	2.0	0.2	0.1	0.4	1.1	-0.1
Leg pain on walking	1.2	1.5	7.7	-1.1	0.0	-1.4	1.4	1.1	0.9	-2.8	1.4	-1.4	-1.0	-1.1	-1.3	1.2	-1.0	-0.7	-1.2	-1.1	0.3	-0.9	-1.3	-1.3
Qualifications: NVQ or HND or HNC or equivalent	0.6	0.7	4.1	-1.7	1.1	-0.1	1.2	0.9	1.0	-0.3	-0.1	-1.1	0.5	-0.0	-0.1	0.4	-0.6	-0.5	2.0	-0.2	-0.9	-0.0	-0.3	-0.6
Commuting to job workplace: Car/motor vehicle	0.4	0.4	2.5	-0.4	-1.5	0.2	0.6	1.3	-0.3	0.2	-0.4	-0.6	0.2	0.3	-0.3	0.3	0.4	-0.0	1.6	0.5	0.5	0.4	0.2	0.3
Illness, injury, bereavement, stress in last 2 years	0.9	1.1	2.5	1.3	-0.8	1.1	-0.2	-0.8	-1.1	1.5	-1.5	0.2	1.0	1.1	1.5	1.6	0.8	1.3	0.2	1.6	0.8	0.5	0.9	0.8
Medication: Aspirin	1.5	1.9	5.4	-2.3	1.4	-1.4	2.3	2.1	0.1	-0.0	1.0	-2.2	-1.6	-1.3	-1.8	-0.0	-0.8	-2.0	0.2	-1.2	0.1	-1.3	0.2	-1.0
Supplements: Vitamin C	0.9	1.0	5.3	-0.9	0.7	-0.9	0.5	0.4	1.3	-2.3	1.2	-0.5	-0.7	-1.0	-0.8	-0.7	-1.0	-0.9	-0.1	-0.9	-1.2	-1.2	-1.1	-1.0
Knee pain experienced in last month	0.5	0.8	3.7	-1.9	1.4	-0.6	0.8	1.1	0.5	-1.5	0.7	-0.9	-0.2	-0.4	-0.8	-0.6	-0.4	-0.7	1.2	-0.2	-0.5	-0.1	0.3	-0.7
Hypertension (Self-reported)	7.9	22.0	34.0	-3.0	5.2	-5.7	3.4	4.0	4.2	-4.0	5.3	-3.4	-5.8	-5.6	-5.6	-4.1	-5.0	-5.8	-2.8	-5.5	-4.1	-5.4	-4.0	-4.7
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.5	0.6	2.7	-0.3	1.3	-0.7	-0.1	0.6	1.2	-1.6	0.8	0.1	-0.1	-0.6	-0.8	-1.1	-0.6	-0.4	0.3	-0.6	-1.3	-0.3	-0.8	-0.7
Illnesses of father: Heart disease	0.8	1.0	3.6	0.4	-0.6	1.0	0.1	-0.2	-0.7	0.5	-1.2	-0.0	1.9	1.5	0.7	0.9	1.2	0.7	1.6	1.0	1.1	1.6	1.3	0.5
Illnesses of siblings: Diabetes	2.3	2.8	6.8	-1.8	2.5	-1.6	2.4	2.6	1.9	-0.9	0.7	-2.3	-1.0	-1.3	-0.6	-1.1	-1.6	-2.2	1.6	-1.1	-1.7	-1.1	-0.1	-1.9
Smoking status: Previous	0.4	0.7	2.1	-1.2	1.3	-0.4	0.5	1.4	0.7	-0.6	0.5	-0.4	0.1	-0.3	-1.4	-1.3	-0.2	-0.9	0.9	-0.9	-0.4	-0.1	-0.2	-0.7
Forced expiratory volume in 1-second (FEV1), predicted	1.4	2.8	8.0	2.4	-2.8	1.5	-2.6	-2.2	-0.5	1.5	-1.7	2.7	1.9	1.5	1.2	0.7	1.2	2.3	-0.5	1.3	0.6	1.3	-0.2	1.0
Whole body fat-free mass	0.7	4.1	8.5	-1.9	0.4	-2.5	1.8	1.9	2.5	-2.9	2.1	-1.8	-1.4	-1.9	-2.4	-0.4	-2.5	-2.1	-1.2	-2.7	-1.1	-1.6	-2.2	-2.6
Leg fat-free mass (right)	0.3	1.7	6.1	-1.4	-0.3	-1.5	0.7	0.5	1.6	-2.5	1.3	-0.7	-0.8	-1.3	-1.6	-0.3	-1.7	-0.9	-1.3	-1.8	-0.4	-0.9	-1.5	-1.7
Arm fat percentage (left)	0.4	1.6	8.9	-3.0	0.5	-0.9	0.3	0.2	1.7	-2.1	1.6	-0.3	-1.0	-1.4	-1.4	-0.8	-1.4	-0.3	0.3	-0.9	-1.2	-0.8	-1.1	-1.4
Average weekly red wine intake	2.4	3.5	8.0	2.8	-1.8	2.1	-1.9	-1.8	-2.1	1.3	-2.0	2.0	1.5	1.9	2.2	0.9	1.9	2.1	-0.4	1.9	1.6	1.7	1.7	2.1
Handedness (chirality/laterality): Left-handed	1.0	1.2	2.5	-1.1	1.0	-1.3	1.3	0.0	1.5	0.2	0.7	-1.3	-1.0	-1.2	-0.3	-1.6	-1.1	-1.6	0.3	-1.0	-1.4	-1.0	-0.4	-1.5
Mood swings	1.0	1.8	5.6	-0.3	1.4	-1.5	0.6	1.2	0.2	-1.2	1.6	-0.7	-2.1	-1.8	-1.9	-2.4	-1.0	-1.6	-1.3	-1.5	-0.5	-1.1	-0.6	-0.9
Loneliness, isolation	0.5	0.6	2.0	-0.5	1.4	-0.8	0.8	0.5	0.3	-0.4	0.7	-0.8	-0.9	-0.9	-1.1	-0.8	-0.4	-1.3	-0.7	-1.4	0.2	-0.5	-0.1	-0.2
Long-standing illness, disability or infirmity	2.0	3.1	5.3	-1.9	1.6	-2.0	0.8	-0.0	1.9	-2.3	1.8	-0.7	-2.0	-2.1	-2.1	-2.3	-1.8	-2.1	-1.0	-2.1	-1.5	-1.9	-1.3	-1.8
Ever had bowel cancer screening	0.5	0.5	2.8	-0.7	1.7	-0.5	0.1	-0.1	-0.0	-0.9	1.1	-0.2	-1.1	-0.8	-0.7	-0.9	-0.6	-0.6	-0.5	-1.1	-0.1	-0.6	0.2	-0.1
Diabetes diagnosed by doctor	5.8	9.5	17.1	-3.2	3.1	-3.6	2.5	1.0	2.6	-3.0	3.6	-2.5	-4.1	-3.9	-3.4	-3.0	-3.3	-3.9	-1.2	-3.5	-2.4	-3.9	-1.4	-2.9
Ever had stillbirth, spontaneous miscarriage or termination	0.2	0.2	1.1	0.2	0.1	0.4	-0.8	-1.1	-0.4	0.3	0.3	0.8	0.2	0.2	-0.0	-0.4	0.3	0.5	-0.3	0.2	-0.0	0.2	0.2	0.5
Friendships satisfaction	1.2	1.4	3.8	-0.2	0.4	1.2	0.3	1.1	-0.7	1.5	-1.8	-0.4	1.8	1.3	0.9	1.0	1.5	0.6	1.7	1.2	0.9	1.9	1.1	1.1
Qualifications: nursing, teaching	0.2	0.3	2.1	-0.6	1.5	-0.6	0.4	0.2	0.3	-0.6	0.4	-0.3	-0.5	-0.4	-0.6	-1.0	-0.4	-0.7	-0.1	-0.4	-0.6	-0.3	-0.1	-0.5
Commuting to job workplace: Walk	1.7	1.8	5.3	1.3	-0.7	1.4	-1.1	-1.5	-1.7	2.3	-1.2	1.1	1.1	1.3	1.5	0.5	1.3	1.6	0.4	1.4	1.0	1.3	1.6	1.5
Eye problems/disorders: Cataract	1.5	1.8	4.2	-1.7	2.0	-1.5	0.5	1.3	1.6	-1.0	1.2	-0.5	-1.0	-1.2	-1.5	-0.2	-1.8	-1.0	-0.8	-1.7	-1.1	-1.2	-1.7	-1.5
Mouth/teeth dental problems: Mouth ulcers	2.6	4.1	13.7	-2.9	2.4	-1.3	3.7	2.1	1.2	-0.2	1.5	-3.7	-1.6	-1.7	-1.8	-0.7	-0.9	-2.8	3.4	-1.2	-0.9	-1.5	1.0	-1.0
Medication for cholesterol	6.6	10.1	20.1	0.9	-2.8	3.7	-1.9	-2.4	-2.4	3.8	-4.2	1.9	4.5	3.9	4.1	3.7	3.2	3.6	2.3	3.3	2.4	3.6	2.6	2.7
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.9	1.0	4.4	-0.5	-1.0	-0.3	2.1	1.7	-0.2	0.3	-0.3	-2.1	-0.5	-0.3	0.3	-0.1	-0.1	-1.2	2.1	0.5	0.5	-0.5	1.0	0.0
Back pain experienced in last month	0.6	0.8	4.6	-0.6	-0.9	1.0	-0.5	-0.8	-0.2	-0.8	-0.9	0.5	1.6	1.2	-0.2	-0.3	1.1	0.3	2.1	0.6	0.6	0.7	1.0	0.6
Mineral and other dietary supplements	0.4	0.6	1.7	1.3	-1.1	0.6	-1.1	-1.1	-0.8	0.6	-0.6	1.1	0.0	0.3	0.7	-0.5	0.5	0.6	-0.6	0.5	0.3	0.6	0.6	0.6
Breast cancer (self-reported)	0.1	0.2	1.2	0.3	0.2	0.2	-0.0	-0.5	-0.3	1.1	0.0	0.0	0.1	0.2	0.2	-0.1	0.4	0.5	0.3	0.6	0.3	0.3	0.7	0.2
Asthma (self-reported)	3.7	7.3	11.5	-3.2	2.5	-3.2	2.9	2.3	2.9	-2.3	2.6	-2.9	-2.8	-3.0	-2.3	-1.8	-3.2	-3.4	0.2	-2.5	-2.9	-3.2	-1.7	-3.1
Osteoporosis (self-reported)	0.5	0.6	2.2	1.0	-1.5	0.3	-0.7	-1.4	-1.0	1.2	-0.8	0.6	-0.3	0.2	1.2	-0.8	0.1	0.4	-0.8	0.8	0.4	0.1	0.5	0.2
Osteoarthritis (self-reported)	0.4	0.6	2.5	-1.4	0.2	0.7	0.5	-0.5	-0.4	-0.3	-0.8	-0.4	0.8	0.6	-0.0	-0.5	0.9	-0.3	1.6	0.3	0.6	0.7	1.4	0.6
Medication: Aspirin	2.1	2.7	6.8	-2.4	1.5	-1.8	2.6	2.6	0.3	-0.3	1.1	-2.5	-1.9	-1.6	-2.1	0.0	-1.2	-2.3	-0.0	-1.5	0.1	-1.6	-0.3	-1.4
Medication: Gliclazide	6.5	7.3	11.5	-2.9	2.8	-3.3	2.1	1.5	2.5	-3.3	3.4	-2.1	-3.2	-3.2	-2.9	-2.3	-2.7	-3.2	-1.1	-3.0	-2.5	-2.8	-2.0	-2.7
Illnesses of father: None of the above (group 1)	0.1	0.2	0.6	-0.3	0.2	0.0	-0.4	0.5	-0.1	-0.2	0.2	0.5	-0.8	-0.5	-0.6	-0.7	0.2	-0.1	-0.5	-0.0	-0.3	-0.5	-0.0	0.2
Smoking status: Current	0.5	0.7	2.3	0.7	-0.7	0.7	-0.2	-1.2	-0.5	1.3	-1.5	0.1	0.7	0.8	1.4	1.5	0.5	0.6	0.1	0.9	0.5	0.5	0.5	0.5
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.6	1.3	5.4	-2.3	1.7	-1.1	1.1	0.9	1.3	-1.0	1.5	-1.1	-1.1	-1.2	-0.4	-0.1	-1.2	-0.6	1.1	-0.3	-1.0	-1.4	-0.0	-0.8
Whole body water mass	0.7	4.1	8.4	-1.9	0.4	-2.5	1.9	2.0	2.6	-2.9	2.1	-1.9	-1.4	-1.9	-2.4	-0.3	-2.4	-2.1	-1.1	-2.7	-1.1	-1.6	-2.1	-2.7
Leg predicted mass (right)	0.3	1.5	5.4	-1.3	-0.3	-1.4	0.6	0.5	1.5	-2.3	1.2	-0.6	-0.7	-1.2	-1.5	-0.3	-1.6	-0.8	-1.2	-1.7	-0.4	-0.8	-1.5	-1.6
Arm fat mass (left)	0.7	2.9	8.8	-3.0	0.7	-1.6	1.1	1.0	2.4	-2.7	2.1	-1.1	-1.4	-1.9	-2.0	-0.9	-1.9	-1.2	0.2	-1.6	-1.5	-1.3	-1.5	-2.0
Number of self-reported non-cancer illnesses	6.8	11.8	20.4	-3.8	4.1	-3.9	2.4	2.2	2.8	-2.0	3.6	-2.3	-4.3	-4.1	-4.5	-4.0	-3.2	-4.5	-1.8	-4.1	-2.8	-3.7	-2.1	-3.5
Average weekly champagne plus white wine intake	0.2	0.3	1.4	0.8	0.1	-0.2	0.3	0.9	-0.3	0.6	0.3	-0.3	0.4	0.3	-0.9	0.5	0.6	-0.2	-1.2	-0.3	0.3	0.7	-1.0	-0.0
Miserableness	0.6	1.0	2.4	1.0	0.0	1.1	-0.8	-0.7	-1.3	0.7	-1.6	0.7	1.2	1.1	0.6	-0.4	1.3	0.7	0.8	0.8	1.2	1.2	1.2	1.0
Guilty feelings	0.4	0.5	1.9	-0.7	1.0	-0.5	1.3	1.2	-0.3	-0.1	0.7	-1.4	0.0	-0.0	-1.2	0.4	0.4	-0.8	0.5	-0.5	0.9	0.3	0.3	-0.3
Wears glasses or contact lenses	0.4	0.5	2.3	-1.5	0.8	-0.7	-0.0	0.3	1.1	-0.4	0.5	-0.0	-0.2	-0.6	-0.9	0.0	-0.8	-0.3	-0.1	-0.9	-0.5	-0.4	-0.6	-1.0
Ever taken oral contraceptive pill	0.4	0.4	2.1	-1.5	-0.1	-0.4	0.5	1.3	0.4	0.6	-0.2	-0.5	-0.4	-0.4	-0.2	-0.7	-0.5	-0.9	-0.0	-0.8	-0.5	-0.1	-0.2	-0.9
Hearing aid user	2.1	2.4	6.4	-0.8	1.2	-1.9	1.6	0.2	1.3	-0.7	2.3	-1.6	-2.5	-2.1	-1.4	-1.3	-1.7	-1.8	-0.8	-1.2	-0.9	-2.2	-0.7	-1.4
Mother’s age at death	0.2	0.3	1.7	-0.6	0.9	-0.3	-0.3	-0.7	-0.0	-0.6	0.3	0.3	-0.5	-0.4	-0.6	-1.3	-0.1	-0.6	-0.2	-0.7	-0.3	-0.6	0.3	-0.2
Financial situation satisfaction	0.4	0.5	1.7	0.6	-1.2	0.6	-0.1	-0.2	-0.3	1.1	-0.8	0.0	1.0	0.8	0.7	-0.0	0.6	0.4	1.3	0.6	-0.1	1.0	0.9	0.1
Tinnitus: Yes, now most or all of the time	0.1	0.1	0.5	-0.0	0.5	-0.3	0.1	0.0	0.3	-0.7	0.4	-0.2	-0.2	-0.3	0.2	-0.4	-0.3	-0.1	-0.3	0.2	-0.3	0.1	-0.5	-0.5
Commuting to job workplace: Public transport	0.2	0.2	1.2	0.4	1.1	-0.1	-0.6	-0.9	0.2	-0.1	0.3	0.5	0.1	-0.1	-0.2	-0.3	0.1	-0.1	-0.9	-0.6	-0.5	-0.0	-0.0	-0.1
Eye problems/disorders: Glaucoma	0.8	1.0	4.4	0.2	0.7	-0.8	-0.4	0.1	0.7	-1.3	0.8	0.4	-0.8	-0.7	-1.4	-1.4	-0.7	-0.9	-2.1	-1.8	0.1	-0.3	-1.1	-0.9
Medication: Blood pressure	6.7	12.8	21.5	-1.5	4.0	-4.2	1.7	2.7	3.1	-4.2	4.5	-1.6	-4.6	-4.3	-4.4	-3.6	-3.8	-3.7	-2.6	-3.8	-3.4	-4.2	-3.3	-3.2
Pain type(s) experienced in last month: Hip pain	0.2	0.2	1.6	-0.2	-0.6	0.4	-0.3	-0.5	-0.1	-1.3	-0.5	0.3	0.3	0.3	0.1	0.4	0.2	0.4	0.0	0.1	0.9	0.1	0.3	0.5
Supplements: Fish oil (including cod liver oil)	0.1	0.1	1.1	0.3	-0.8	-0.0	0.3	0.3	0.2	0.1	-0.0	-0.3	0.5	0.3	0.0	1.0	0.0	0.4	0.2	0.4	0.2	0.1	-0.5	0.1
High cholesterol (Self-reported)	0.3	0.5	2.0	0.8	1.0	-0.2	-0.3	0.3	-0.9	-0.7	0.7	0.2	-1.4	-0.8	-1.2	-0.9	0.3	-0.2	-1.1	-0.3	0.4	-0.4	0.3	0.8
Medication: Bendroflumethiazide	4.2	6.3	13.3	-1.4	2.6	-2.9	0.6	1.7	2.3	-2.2	3.0	-0.6	-3.0	-2.9	-3.6	-2.8	-2.6	-2.5	-2.4	-3.0	-2.3	-2.8	-2.7	-2.5
Medication: Paracetamol	3.1	4.8	8.8	-1.9	2.3	-2.6	1.4	0.5	1.8	-2.6	2.8	-1.3	-2.7	-2.6	-2.4	-2.7	-2.1	-2.8	-1.5	-3.0	-1.5	-2.3	-1.1	-2.0
Medication: Lisinopril	4.1	5.4	10.0	-1.1	2.0	-2.5	-0.3	0.9	2.1	-2.3	2.9	0.4	-3.2	-2.9	-2.9	-2.9	-2.1	-2.2	-2.6	-3.0	-2.2	-3.0	-2.2	-1.8
Medication: Atorvastatin	0.9	1.1	4.1	-0.6	0.5	-0.9	0.6	0.9	-0.2	0.4	0.2	-0.6	-1.7	-1.2	-2.0	-1.9	-0.6	-1.8	-1.2	-1.3	-0.1	-1.3	-0.4	-0.2
Illnesses of father: High blood pressure	0.8	1.0	3.6	-0.2	0.7	-1.1	1.3	1.6	1.1	-1.9	0.9	-1.2	-0.1	-0.4	-0.9	-0.1	-0.8	-1.3	-0.0	-1.2	-0.5	-0.4	-1.0	-1.0
Alcohol drinker status: Never	3.5	4.2	6.6	-1.4	2.3	-2.2	1.5	1.6	2.4	-2.6	2.4	-1.5	-1.8	-2.2	-2.4	-1.9	-2.0	-2.4	-0.4	-2.1	-2.4	-2.2	-1.7	-2.4
Ever smoked	0.1	0.2	1.3	-0.2	0.2	0.3	0.5	1.0	-0.1	0.6	-0.6	-0.5	0.6	0.4	-0.4	-0.3	0.4	-0.3	1.2	0.0	-0.1	0.4	0.4	-0.1
Basal metabolic rate	0.7	3.8	8.4	-2.1	0.3	-2.3	1.7	1.8	2.6	-2.9	2.0	-1.7	-1.3	-1.9	-2.3	-0.4	-2.4	-1.9	-0.8	-2.5	-1.2	-1.6	-2.1	-2.6
Leg fat percentage (left)	1.5	5.3	13.5	-3.7	1.9	-2.2	1.9	2.0	3.0	-2.7	2.9	-1.9	-1.9	-2.5	-2.8	-1.2	-2.3	-2.0	0.9	-2.0	-2.2	-2.0	-1.9	-2.6
Arm fat-free mass (left)	1.6	8.0	13.0	-3.0	1.5	-3.3	3.2	3.1	3.6	-3.5	2.9	-3.2	-2.0	-2.7	-3.3	-0.5	-3.1	-3.3	-0.1	-3.4	-1.8	-2.4	-2.4	-3.6
Number of operations (self-reported)	3.5	5.2	9.2	-3.0	2.7	-2.6	2.1	1.7	2.1	-1.4	2.7	-2.1	-2.6	-2.6	-2.4	-2.8	-2.1	-3.0	0.5	-2.1	-2.3	-2.3	-1.0	-2.2
Average weekly beer plus cider intake	1.4	2.1	9.0	1.1	-1.5	1.2	-1.8	-2.6	-0.9	3.0	-1.6	1.9	0.6	0.9	2.0	0.2	0.6	1.5	-0.7	1.1	0.2	0.8	0.8	1.1
Irritability	0.1	0.2	0.8	0.3	0.2	0.3	0.1	0.5	-0.6	-0.0	-0.3	-0.2	0.2	0.3	-0.6	0.3	0.4	0.1	0.3	0.3	0.9	0.1	0.5	0.4
Risk taking	1.0	1.5	3.7	0.5	-1.9	0.9	0.9	0.9	-1.4	1.0	-1.4	-0.9	1.3	1.4	1.2	1.1	1.4	0.3	1.4	1.2	1.4	1.4	1.7	0.9
Ever had prostate specific antigen (PSA) test	0.4	0.5	2.0	-0.6	0.4	-0.5	1.3	1.4	-0.2	0.6	-0.7	-1.2	-0.3	-0.1	-0.1	0.6	-0.5	-1.1	-0.3	-0.6	0.9	-0.2	0.0	-0.5
Fractured/broken bones in last 5 years	1.0	1.4	3.8	-0.4	-0.3	-1.2	-0.1	0.7	1.1	-1.6	1.4	0.2	-1.3	-1.4	-1.0	-1.9	-1.3	-1.3	-0.9	-1.3	-1.4	-1.4	-1.1	-1.0
Age started oral contraceptive pill	0.3	0.3	5.1	-2.3	0.8	-0.0	-0.0	-0.0	0.2	0.7	-0.2	-0.0	-0.1	-0.2	-0.1	0.1	-0.5	0.1	-0.1	-0.4	-0.2	0.0	-0.2	-0.3
Diastolic blood pressure, automated reading	6.2	19.4	29.3	-1.7	4.2	-5.4	2.5	2.7	4.9	-3.7	5.4	-2.4	-5.1	-5.3	-4.9	-3.4	-4.9	-4.8	-3.0	-4.8	-5.3	-5.2	-4.8	-5.0
Ever depressed for a whole week	0.6	0.8	4.8	-2.2	0.4	-0.2	1.2	2.0	0.1	-0.2	0.1	-1.2	-0.5	-0.4	-1.0	0.6	-0.0	-0.6	1.2	0.0	-0.2	-0.3	0.3	0.0
Unable to work because of sickness or disability	0.1	0.2	0.6	-0.4	0.0	0.1	0.6	0.8	-0.3	0.3	-0.2	-0.5	-0.2	-0.1	-0.5	-0.3	0.5	-0.4	0.5	-0.2	0.5	0.0	0.4	0.4
Commuting to job workplace: Cycle	0.5	0.5	3.2	-0.1	-0.3	-0.6	-0.6	0.1	0.5	-1.8	1.1	0.6	-0.4	-0.6	-1.0	-0.7	-0.4	-0.1	-0.9	-0.6	-0.7	-0.7	-0.8	-0.8
Myopia	0.1	0.2	1.8	-0.6	1.3	-0.1	0.2	-0.2	0.2	0.1	-0.1	-0.4	-0.0	-0.1	0.5	0.8	-0.5	-0.1	0.2	-0.0	-0.4	-0.3	0.6	-0.2
Vascular/heart problems diagnosed by doctor	8.0	21.7	34.2	3.1	-5.4	5.6	-3.4	-4.4	-4.2	3.9	-5.1	3.4	5.8	5.5	5.7	4.1	4.9	5.8	2.4	5.5	4.0	5.3	3.7	4.6
Cholesterol lowering medication	0.4	0.7	2.5	1.6	0.5	-0.2	0.1	-0.0	-1.0	-1.2	0.8	-0.1	-1.5	-0.7	-1.0	-1.2	0.2	-0.2	-0.9	0.1	0.8	-0.6	0.4	0.8
Medication: Omeprazole (e.g. Zanprol)	2.1	2.6	5.2	-1.5	1.4	-1.7	0.5	0.5	1.3	-2.3	2.0	-0.7	-2.0	-1.9	-2.0	-1.9	-1.8	-1.5	-1.3	-1.8	-1.4	-2.0	-1.5	-1.4
Pain experienced in last month	1.4	2.3	6.3	2.4	-1.5	1.0	-2.3	-1.3	-0.9	2.5	-1.2	2.2	0.8	1.0	1.5	1.1	0.6	2.2	-2.3	1.2	0.3	1.0	-0.7	0.6
Supplements: Calcium	0.6	0.6	1.7	-1.3	0.8	-0.7	0.8	0.4	1.1	-0.4	0.3	-0.9	-0.5	-0.8	-0.2	-1.2	-0.6	-1.2	0.5	-0.6	-1.1	-0.5	-0.2	-1.0
Basal cell carcinoma (self-reported)	0.6	0.8	1.7	-0.3	1.3	-1.1	0.6	0.7	0.5	-0.4	1.0	-0.6	-0.9	-0.9	-1.2	-0.6	-0.8	-0.9	-1.0	-0.8	-0.9	-1.0	-1.2	-0.8
Heart attack/myocardial infarction (self-reported)	0.6	0.8	4.0	-0.1	-0.8	0.9	0.0	0.2	-0.6	1.1	-1.3	-0.0	1.3	1.1	0.7	0.3	1.0	0.2	2.0	0.9	0.5	1.2	0.9	0.6
Deep venous thrombosis (DVT) (self-reported)	0.3	0.4	1.2	-1.1	0.0	0.8	-0.0	0.2	-0.9	0.3	-1.1	0.0	0.4	0.7	0.8	0.1	0.6	0.2	0.8	0.8	0.7	0.6	0.9	0.7
Heart disease (siblings)	0.8	1.0	4.7	-0.5	-0.5	0.4	1.2	1.2	-0.8	0.9	-0.7	-1.3	0.7	0.8	0.8	1.6	0.9	0.1	2.2	1.3	0.8	0.9	1.0	0.8
Alcohol drinker status: Previous	1.4	1.6	3.2	-1.6	1.7	-1.2	1.3	1.8	0.6	-0.9	1.2	-1.3	-1.8	-1.6	-1.5	-1.3	-1.2	-1.5	0.0	-1.0	-0.8	-1.5	-0.5	-0.7
Pack years of smoking	1.6	2.4	6.7	-1.3	0.4	-1.6	2.5	2.6	0.7	-1.8	1.1	-2.6	-1.9	-1.6	-1.7	-0.5	-1.4	-2.1	0.2	-1.0	-0.3	-1.7	-0.5	-1.2
Impedance of whole body	4.1	20.8	32.7	4.8	-4.4	5.5	-3.7	-3.1	-4.5	5.7	-5.3	3.6	5.0	5.1	5.1	3.0	5.1	5.2	2.7	5.7	3.0	4.7	3.3	5.1
Leg fat mass (left)	1.7	6.6	13.8	-3.7	1.6	-2.7	2.0	1.9	3.5	-3.5	3.2	-2.0	-2.2	-2.9	-3.1	-1.0	-2.8	-2.2	0.0	-2.6	-2.3	-2.4	-2.4	-3.1
Arm predicted mass (left)	1.6	8.2	13.8	-3.0	1.4	-3.4	3.1	3.1	3.7	-3.4	2.9	-3.1	-2.0	-2.8	-3.2	-0.6	-3.2	-3.4	-0.4	-3.6	-1.9	-2.4	-2.5	-3.7