Best TWAS P=2.55e-15 · Best GWAS P=7.15e-33 conditioned to 9.1e-17
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | NDUFS4 | 0.13 | 0.03 | bslmm | 474 | 0.10 | 3.3e-12 | -0.67 | 5.5 | 3.7e-08 | 0.32 | 0.87 | 0.13 | FALSE |
| 2 | GTEx | Artery Tibial | CTD-2366F13.1 | 0.15 | 0.10 | enet | 24 | 0.11 | 7.0e-09 | 3.31 | 5.3 | 1.0e-07 | 0.23 | 1.00 | 0.00 | TRUE |
| 3 | GTEx | Muscle Skeletal | NDUFS4 | 0.07 | 0.05 | lasso | 2 | 0.04 | 1.2e-04 | 6.24 | -5.5 | 3.8e-08 | -0.51 | 0.43 | 0.02 | FALSE |
| 4 | The Cancer Genome Atlas | Prostate Adenocarcinoma | NDUFS4 | 0.05 | 0.02 | enet | 8 | 0.03 | 1.4e-04 | 8.24 | 7.9 | 2.6e-15 | 0.45 | 0.01 | 0.96 | TRUE |