[Hub]/) : Traits : Impedance of arm (right) :

chr5:62,764,129-65,866,903

Best TWAS P=1.84e-12 · Best GWAS P=2.18e-19 conditioned to 4.79e-13

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous NLN 0.09 0.11 enet 12 0.10 1.6e-08 5.2 5.4 5.8e-08 0.21 1.00 0.00 FALSE
2 GTEx Adipose Subcutaneous RNF180 0.04 0.02 lasso 5 0.01 1.0e-01 5.5 -5.6 2.3e-08 -0.09 0.05 0.92 FALSE
3 GTEx Artery Aorta RNF180 0.06 0.00 lasso 2 -0.01 9.5e-01 5.5 -5.5 3.4e-08 -0.09 0.05 0.80 FALSE
4 GTEx Brain Cerebellum TRIM23 0.16 0.09 lasso 6 0.07 4.7e-03 5.1 -5.2 1.6e-07 -0.18 0.18 0.06 FALSE
5 GTEx Brain Hippocampus PPWD1 0.22 0.15 enet 19 0.19 3.7e-05 4.2 -5.1 3.1e-07 -0.21 0.22 0.05 FALSE
6 GTEx Breast Mammary Tissue NLN 0.17 0.04 enet 13 0.06 3.6e-04 5.1 5.5 3.6e-08 0.17 0.36 0.04 FALSE
7 GTEx Cells Transformed fibroblasts NLN 0.17 0.03 lasso 9 0.06 2.3e-05 5.1 5.5 3.6e-08 0.10 0.95 0.00 FALSE
8 GTEx Esophagus Mucosa NLN 0.14 0.11 lasso 7 0.11 9.8e-08 5.1 5.3 1.3e-07 0.20 0.98 0.00 FALSE
9 GTEx Testis RNF180 0.10 0.08 lasso 5 0.06 1.8e-03 5.7 -6.1 1.3e-09 -0.07 0.05 0.93 TRUE
10 GTEx Thyroid RNF180 0.09 0.09 lasso 3 0.10 7.7e-08 5.6 -5.6 2.3e-08 -0.11 0.05 0.95 FALSE
11 METSIM Adipose SGTB 0.03 0.00 bslmm 384 0.01 4.7e-03 -2.8 7.0 1.8e-12 0.22 0.22 0.06 TRUE
12 NTR Blood NLN 0.04 0.03 lasso 3 0.03 3.4e-09 5.0 5.2 1.6e-07 0.19 1.00 0.00 FALSE
13 ROSMAP Brain Pre-frontal Cortex RNF180 0.06 0.06 lasso 5 0.07 2.7e-09 5.5 -5.2 1.7e-07 -0.10 0.07 0.93 FALSE
14 The Cancer Genome Atlas Breast Invasive Carcinoma NLN 0.04 0.02 lasso 7 0.02 3.2e-05 5.0 5.6 2.3e-08 0.14 0.00 0.99 FALSE
15 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma NLN 0.06 0.00 blup 101 0.03 3.8e-04 4.2 5.1 2.6e-07 0.03 0.02 0.84 FALSE
16 The Cancer Genome Atlas Lung Squamous Cell Carcinoma RNF180 0.02 0.02 blup 58 0.02 2.0e-03 5.5 -5.9 2.9e-09 -0.10 0.03 0.68 FALSE