TWAS hub - RNF180

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.0310	0.0140	1.3e-03	0.019	0.014	0.009	0.015	0.012	2.0e-03	7.3e-03	2.6e-02	5.0e-03	1.0e-02
2	GTEx	Adipose Subcutaneous	0.0430	0.0200	2.6e-03	0.024	NA	0.002	NA	0.006	4.3e-03	NA	2.0e-01	NA	1.0e-01
3	GTEx	Artery Aorta	0.0630	0.0340	8.3e-03	0.001	NA	-0.005	NA	-0.005	2.7e-01	NA	9.5e-01	NA	9.5e-01
4	GTEx	Brain Cerebellar Hemisphere	0.1230	0.0550	3.0e-03	0.150	NA	0.132	NA	0.140	1.2e-04	NA	2.9e-04	NA	2.0e-04
5	GTEx	Brain Cerebellum	0.1730	0.0760	9.9e-04	0.101	NA	0.038	NA	0.074	6.6e-04	NA	2.8e-02	NA	3.3e-03
6	GTEx	Brain Hypothalamus	0.2970	0.0970	1.3e-03	-0.013	NA	0.005	NA	0.009	8.8e-01	NA	2.4e-01	NA	2.0e-01
7	GTEx	Nerve Tibial	0.0926	0.0290	1.6e-06	0.052	NA	0.035	NA	0.037	1.5e-04	NA	1.6e-03	NA	1.2e-03
8	GTEx	Testis	0.0980	0.0410	5.4e-04	0.083	NA	0.022	NA	0.055	1.6e-04	NA	3.5e-02	NA	1.8e-03
9	GTEx	Thyroid	0.0890	0.0300	2.5e-06	0.092	NA	0.073	NA	0.097	1.7e-07	NA	3.0e-06	NA	7.7e-08
10	ROSMAP	Brain Pre-frontal Cortex	0.0586	0.0204	6.2e-07	0.063	0.053	0.035	0.054	0.070	1.6e-08	2.4e-07	2.2e-05	1.6e-07	2.7e-09
11	TCGA	Lung Squamous Cell Carcinoma	0.0152	0.0105	6.1e-03	0.018	0.020	0.011	NA	0.011	3.4e-03	2.0e-03	1.8e-02	NA	1.7e-02
12	TCGA	Prostate Adenocarcinoma	0.0321	0.0238	7.3e-04	0.015	0.029	0.031	NA	0.019	8.4e-03	4.8e-04	3.1e-04	NA	4.2e-03

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12
Worry (Nagel 2018)	7.7	16.3	21.9	4.7	3.9	4.3	4.1	4.4	2.2	3.4	4.5	4.1	4.3	4.4	3.5
Tense / ‘highly strung’	6.9	11.4	23.6	4.9	2.7	4.0	3.1	3.0	0.8	2.6	4.3	2.9	3.8	3.9	2.9
Neuroticism	5.9	14.2	23.1	4.8	3.3	4.0	3.9	3.5	2.3	3.8	4.3	3.2	4.3	4.1	3.2
Diverticular disease/diverticulitis (self-reported)	5.8	6.8	10.2	2.2	3.2	3.0	2.3	2.4	2.1	1.9	2.9	2.9	2.6	3.1	2.4
Impedance of arm (right)	5.8	26.8	36.8	-4.9	-5.6	-5.5	-4.8	-4.7	-4.9	-3.7	-6.1	-5.6	-5.2	-5.9	-4.8
Impedance of arm (left)	5.7	26.4	36.8	-4.8	-5.2	-5.5	-5.0	-4.9	-5.0	-3.9	-6.1	-5.2	-5.3	-5.9	-4.4
Unable to work because of sickness or disability	5.5	7.1	10.1	2.5	3.2	2.7	2.6	2.8	1.4	2.8	2.4	3.2	2.6	3.0	2.2
Frequency of tiredness / lethargy in last 2 weeks	5.3	8.6	17.0	4.1	2.4	3.3	3.3	3.0	0.9	2.7	2.6	2.6	3.2	3.2	2.7
Guilty feelings	5.3	8.0	13.3	3.2	2.8	3.0	2.9	3.2	1.5	1.5	3.6	2.9	2.8	3.1	2.6
Commuting to job workplace: Car/motor vehicle	5.1	5.9	8.6	2.9	1.9	2.4	2.9	2.8	1.7	2.5	2.2	2.3	2.5	2.5	2.1
Neuroticism score	4.9	10.2	18.1	4.3	2.8	3.5	3.3	3.3	1.6	3.0	3.6	2.8	3.5	3.5	2.4
Medication: Lisinopril	4.9	6.3	9.4	2.1	2.7	2.4	2.4	2.5	2.0	2.9	2.6	3.1	2.5	2.7	2.2
Schizophrenia (2018)	4.5	9.4	15.8	3.5	2.6	3.5	3.2	3.5	1.6	2.0	4.0	2.9	3.2	3.4	2.8
Tinnitus: Yes, now most or all of the time	4.5	5.2	7.4	2.1	2.5	2.3	2.3	2.4	1.1	2.3	2.5	2.7	2.1	2.5	2.2
Schizophrenia vs Biploar Disorder	4.2	5.6	8.6	1.5	2.7	2.2	2.4	2.1	1.3	2.5	2.9	2.9	2.2	2.8	2.3
Schizophrenia (2014)	4.2	9.2	14.2	3.7	2.5	3.2	3.2	3.5	1.9	2.3	3.8	2.8	3.1	3.1	2.8
Average weekly spirits intake	4.1	5.0	6.5	1.7	2.4	2.2	2.5	2.4	0.6	2.1	2.4	2.5	2.2	2.5	2.5
Commuting to job workplace: Walk	3.9	4.2	7.3	-1.9	-1.8	-1.9	-2.7	-2.2	-1.2	-2.3	-1.8	-1.8	-2.2	-2.1	-2.3
Medication: Omeprazole (e.g. Zanprol)	3.9	4.8	9.5	1.6	2.5	1.4	2.0	1.7	2.2	2.7	1.6	2.7	1.9	2.0	3.1
Impedance of whole body	3.9	19.8	29.8	-3.8	-4.8	-4.9	-4.1	-4.2	-4.7	-2.3	-5.5	-4.8	-4.4	-5.2	-3.8
Other serious medical condition/disability diagnosed by doctor	3.8	5.0	8.2	2.3	2.8	2.5	1.7	1.8	0.9	1.1	2.9	2.7	2.2	2.7	2.2
Seen doctor (GP) for nerves, anxiety, tension or depression	3.7	5.6	8.6	2.4	2.4	2.3	2.5	2.8	0.8	2.1	2.7	2.9	2.3	2.5	1.9
Neuroticism (Nagel 2018)	3.6	8.5	13.5	3.7	2.8	3.1	3.1	2.9	1.3	2.5	3.1	3.1	3.1	3.2	2.5
Number of full sisters	3.6	4.4	7.2	-2.3	-1.8	-1.9	-2.5	-2.6	-2.7	-2.0	-1.6	-2.0	-2.2	-2.0	-1.2
Townsend deprivation index at recruitment	3.5	4.8	6.2	-2.3	-2.0	-2.1	-2.3	-2.4	-1.6	-2.4	-2.5	-2.0	-2.2	-2.4	-2.2
Suffer from ‘nerves’	3.4	5.3	8.4	2.1	2.7	2.1	2.4	2.8	1.6	2.0	2.0	2.9	2.2	2.4	2.0
Chronotype (morning person)	2.9	6.7	11.4	-2.9	-3.0	-2.8	-2.5	-2.9	-1.3	-0.4	-3.4	-2.8	-2.3	-2.9	-2.3
Nervous feelings	2.9	5.5	9.2	3.0	2.5	2.4	2.3	2.6	0.3	2.2	2.4	2.4	2.4	2.6	1.8
Medication for hormone replacement therapy	2.7	3.0	5.3	-0.8	-2.3	-1.7	-1.6	-1.9	-1.8	-1.2	-1.6	-2.3	-1.6	-2.0	-1.5
Seen a psychiatrist for nerves, anxiety, tension or depression	2.7	3.5	6.4	2.3	1.1	2.4	2.0	2.5	-0.5	1.2	1.8	1.5	2.3	2.0	1.5
Body mass index (BMI)	2.6	11.0	16.5	3.0	3.1	4.1	3.7	3.3	2.6	2.0	3.4	2.7	3.9	3.9	3.5
Frequency of tenseness / restlessness in last 2 weeks	2.6	4.1	8.9	2.9	1.7	2.3	1.6	1.8	1.6	0.7	3.0	2.0	2.0	2.3	1.3
Arm predicted mass (left)	2.5	12.6	18.6	3.5	3.2	3.8	3.5	3.5	3.9	2.6	4.3	3.1	3.7	4.0	3.2
Happiness	2.4	3.0	5.2	1.4	1.6	1.5	1.8	2.1	2.3	1.3	1.7	2.0	1.4	1.6	1.6
Breast cancer (self-reported)	2.4	2.9	4.6	2.1	1.2	1.4	2.1	1.9	1.7	1.5	2.1	1.0	1.4	1.6	2.0
Body Mass Index (BMI) (2010)	2.3	3.2	6.5	1.2	2.5	2.1	1.6	1.7	0.8	0.6	2.0	2.2	1.6	2.2	1.7
Tinnitus: Yes, but not now, but have in the past	2.3	2.4	4.5	-0.8	-2.0	-1.3	-1.9	-2.1	-1.0	-1.4	-0.9	-2.1	-1.1	-1.6	-1.7
Length of working week for main job	2.3	2.6	4.1	1.6	1.3	1.9	2.0	1.7	1.7	0.9	1.7	1.4	1.8	1.9	1.0
Loneliness, isolation	2.3	3.2	4.4	2.1	1.7	1.9	2.0	1.8	0.2	2.1	1.7	1.8	1.9	1.9	1.5
Commuting to job workplace: Public transport	2.3	2.7	5.1	-1.1	-2.3	-1.5	-1.7	-1.9	-1.8	-1.5	-1.1	-2.1	-1.3	-1.7	-1.3
Sensitivity / hurt feelings	2.2	3.7	6.7	2.6	1.8	2.0	1.6	1.6	1.0	1.2	2.6	2.2	1.9	2.1	2.0
Forced expiratory volume in 1-second (FEV1), predicted percentage	2.2	4.6	11.2	3.3	1.4	2.7	2.3	2.6	1.0	1.4	2.5	1.2	2.3	2.3	0.9
Arm fat-free mass (left)	2.2	10.9	16.2	3.0	3.1	3.5	3.1	3.1	3.8	2.3	4.0	3.0	3.4	3.7	3.1
Arm predicted mass (right)	2.1	10.5	15.5	3.1	3.1	3.5	3.1	3.1	3.6	2.1	3.9	3.0	3.3	3.6	3.1
Frequency of unenthusiasm / disinterest in last 2 weeks	2.0	2.6	5.6	2.2	1.0	2.0	1.6	1.7	0.2	1.2	2.4	1.2	1.7	1.9	1.1
Hayfever, allergic rhinitis or eczema	2.0	4.2	6.8	-1.2	-2.3	-1.9	-2.0	-1.8	-1.6	-2.6	-1.7	-2.2	-2.1	-2.2	-2.6
Pain all over the body in last month	2.0	2.1	3.6	1.8	1.0	1.7	1.9	1.8	-0.3	1.2	1.0	0.9	1.8	1.5	1.6
Medication: Atorvastatin	2.0	2.5	4.7	-1.1	-1.8	-1.5	-1.6	-2.1	-1.0	-0.8	-1.5	-1.8	-1.3	-1.6	-2.2
Worrier / anxious feelings	1.9	3.6	6.0	2.5	1.5	1.9	2.0	2.2	0.9	2.0	1.8	1.8	2.2	1.9	1.5
Trunk predicted mass	1.9	10.6	16.6	3.0	2.9	3.5	3.2	3.3	4.0	2.2	4.1	3.0	3.3	3.6	2.6
Leg fat percentage (right)	1.9	6.9	11.2	2.5	2.0	3.0	3.3	2.5	2.1	2.7	2.1	1.5	3.3	2.9	2.9
Arm fat-free mass (right)	1.9	9.5	14.6	2.9	3.0	3.4	2.9	3.0	3.5	1.9	3.8	2.9	3.1	3.5	2.9
Leg fat percentage (left)	1.9	6.7	10.4	2.5	2.2	3.0	3.2	2.5	1.8	2.4	2.2	1.6	3.2	2.9	3.0
Bipolar Disorder or Schizophrenia	1.8	4.3	10.0	2.7	1.4	2.5	1.8	2.4	1.5	0.6	3.2	1.6	2.1	2.2	1.6
Impedance of leg (left)	1.8	8.7	14.4	-2.2	-3.2	-3.4	-2.5	-2.9	-3.4	-0.4	-3.8	-3.5	-2.8	-3.5	-2.4
Trunk fat-free mass	1.8	10.5	16.7	3.0	2.9	3.5	3.2	3.2	4.0	2.1	4.1	3.0	3.2	3.6	2.6
Medication: Seretide 50 evohaler	1.8	2.0	5.3	-0.4	-1.8	-0.9	-1.4	-1.5	-2.3	-1.3	-1.2	-1.9	-1.0	-1.3	-1.1
Leg fat mass (right)	1.8	7.1	10.7	2.5	2.1	3.1	3.3	2.7	2.3	2.4	2.3	1.7	3.2	3.0	3.0
Leg fat mass (left)	1.8	7.1	10.2	2.5	2.3	3.1	3.2	2.7	2.0	2.3	2.4	1.8	3.2	3.0	3.0
Depressed Affect (Nagel 2018)	1.7	3.6	7.0	2.6	1.5	1.9	2.3	1.5	0.4	2.6	1.4	1.5	2.3	1.9	1.6
Primary Biliary Cirrhosis	1.7	2.5	3.9	1.8	1.6	1.8	1.7	1.5	-0.4	1.3	1.5	1.4	2.0	1.8	1.6
Impedance of leg (right)	1.7	8.1	13.7	-1.9	-3.4	-3.3	-2.2	-2.7	-3.0	-0.0	-3.7	-3.5	-2.5	-3.4	-2.4
Had other major operations	1.7	2.1	5.6	1.8	1.6	1.3	1.5	1.2	0.6	1.1	0.8	1.4	1.5	1.5	2.4
Depression (self-reported)	1.7	2.0	4.6	1.0	1.7	1.4	1.4	2.0	1.1	0.8	2.1	1.5	1.1	1.4	0.8
Supplements: Fish oil (including cod liver oil)	1.7	2.3	3.8	-2.0	-1.1	-1.8	-1.5	-1.5	-0.1	-1.9	-1.5	-0.9	-1.9	-1.8	-1.1
Chronic bronchitis/emphysema (father)	1.6	1.9	5.7	0.8	2.4	0.7	1.1	0.8	0.6	1.8	0.6	2.2	1.1	1.4	1.1
Illnesses of siblings	1.6	2.3	6.0	-0.7	-1.4	-1.1	-1.5	-1.0	-1.5	-2.4	-0.9	-1.5	-1.6	-1.5	-2.1
Number of full brothers	1.6	2.1	5.1	1.2	1.6	1.4	1.1	0.4	-0.0	1.8	1.1	1.4	1.7	1.7	2.3
Whole body fat-free mass	1.6	9.4	15.4	2.9	2.8	3.4	3.0	3.1	3.5	1.7	3.9	2.8	3.1	3.5	2.5
Whole body water mass	1.6	9.3	15.2	2.7	2.9	3.4	2.9	3.1	3.6	1.6	3.9	2.9	3.0	3.4	2.5
Alcohol drinker status: Never	1.6	1.9	4.0	-0.7	-1.8	-1.0	-0.9	-1.3	-1.8	-0.8	-1.5	-2.0	-1.0	-1.4	-1.7
Basal metabolic rate	1.6	8.8	13.3	2.7	2.7	3.4	3.0	3.0	3.3	1.7	3.6	2.6	3.1	3.4	2.6
BMI	1.5	8.8	13.8	2.6	2.8	3.7	3.6	3.1	2.3	1.3	3.0	2.5	3.5	3.5	2.8
Had menopause	1.5	1.9	3.0	-1.6	-1.5	-1.2	-1.6	-1.6	-0.5	-1.7	-1.5	-1.3	-1.4	-1.5	-0.4
Falls in the last year	1.5	2.0	4.8	2.2	1.4	1.8	1.2	1.1	-0.8	0.9	1.7	1.1	1.5	1.6	0.9
Hair/balding pattern: Pattern 4	1.5	3.6	8.5	1.2	2.2	1.8	1.7	1.6	2.9	1.6	1.7	2.2	2.0	2.1	0.9
Number of children fathered	1.5	1.7	2.9	1.7	0.7	1.6	1.5	1.6	1.3	0.5	1.7	0.9	1.1	1.3	1.2
Mineral and other dietary supplements	1.5	2.0	4.1	1.8	0.8	1.7	1.6	1.4	-0.4	2.0	1.2	0.7	1.8	1.6	0.9
Medication: Blood pressure	1.5	2.8	6.5	1.6	1.7	1.1	1.2	0.7	2.4	2.4	0.7	1.2	1.6	1.6	2.5
Pain type(s) experienced in last month: Hip pain	1.5	1.9	4.6	2.1	0.8	1.4	1.5	1.1	0.6	1.7	1.2	0.9	1.7	1.4	1.3
Illnesses of father: High blood pressure	1.5	1.8	4.4	2.1	0.6	1.6	1.3	1.6	0.5	1.4	1.5	0.9	1.4	1.3	0.9
Pain experienced in last month	1.5	2.6	7.9	-2.8	-1.1	-1.4	-1.6	-1.2	0.2	-2.1	-1.7	-1.4	-1.7	-1.6	-1.2
Taking other prescription medications	1.4	2.2	4.1	1.4	1.7	1.0	1.3	1.0	1.5	1.4	1.5	1.8	1.3	1.4	2.0
Financial difficulties in last 2 years	1.4	1.9	4.6	1.1	2.1	1.0	1.4	1.5	0.4	1.1	0.8	2.1	1.1	1.4	1.4
Loud music exposure frequency	1.4	1.6	2.6	-1.5	-1.6	-1.3	-1.3	-1.6	-0.6	-0.5	-1.2	-1.1	-1.2	-1.3	-1.3
Miserableness	1.4	2.4	4.3	2.0	0.7	1.9	2.1	1.6	0.3	2.0	1.1	0.7	2.0	1.6	1.1
Depression (Nagel 2018)	1.3	2.0	5.6	2.4	0.3	1.5	1.5	1.3	-0.2	1.6	2.1	0.6	1.5	1.4	0.8
Alzheimer’s Disease (in father)	1.3	1.4	3.6	-1.1	-1.0	-1.3	-1.3	-1.1	-1.9	-0.4	-0.9	-1.2	-1.2	-1.3	-0.8
High blood pressure (mother)	1.3	1.8	7.4	0.6	1.5	0.5	1.1	0.4	1.2	1.6	0.8	1.7	1.0	1.1	2.7
Weight	1.3	6.4	9.4	2.3	2.2	3.1	2.8	2.6	2.3	1.4	2.7	2.0	2.9	2.9	2.6
Hip circumference	1.3	5.8	8.2	2.2	2.0	2.9	2.6	2.3	2.0	1.6	2.7	1.8	2.8	2.8	2.8
Lung cancer (father)	1.3	1.5	2.4	-1.5	-1.1	-1.3	-0.9	-0.6	-0.2	-1.5	-1.6	-1.0	-1.4	-1.4	-1.3
Illnesses of mother	1.3	1.6	4.4	-0.8	-1.1	-0.6	-1.5	-0.8	-0.8	-2.1	-0.9	-1.1	-1.3	-1.1	-2.1
Pulse rate, automated reading	1.3	4.3	6.0	2.4	1.9	2.4	2.2	2.1	1.3	1.4	2.4	1.5	2.2	2.4	2.0
Irritability	1.3	2.2	5.1	2.3	1.2	1.5	1.5	0.9	1.2	1.6	1.4	1.3	1.8	1.6	1.2
Allergy or Eczema	1.2	3.0	5.6	-1.1	-1.7	-1.7	-1.8	-1.7	-1.2	-2.1	-1.2	-1.6	-2.0	-1.9	-2.4
High blood pressure	1.2	3.2	10.7	1.7	0.6	1.2	2.1	1.2	1.7	3.3	1.1	0.4	2.2	1.5	2.5
Exposure to tobacco smoke at home	1.2	1.3	3.3	-1.0	-1.4	-0.6	-1.1	-1.2	-0.8	-1.8	-1.0	-1.6	-0.8	-1.1	0.3
Medication: Omeprazole	1.2	1.5	5.1	0.6	1.5	0.5	0.7	0.3	1.7	1.6	0.5	1.3	0.9	0.9	2.2
Medication: Gliclazide	1.2	1.3	3.5	0.8	1.0	1.3	1.3	1.0	0.9	1.0	0.8	0.5	1.4	1.2	1.9
Ever smoked	1.2	2.1	7.3	-2.7	0.6	-1.6	-1.7	-1.4	-0.3	-1.7	-1.0	0.6	-2.1	-1.2	-0.5
Alcohol drinker status: Previous	1.2	1.3	3.2	1.5	0.3	1.1	1.2	0.8	0.9	1.8	0.8	0.3	1.6	1.1	1.4
Hearing difficulty/problems: Yes	1.1	1.7	3.3	0.5	1.8	1.0	1.3	1.5	1.8	1.2	1.2	1.8	0.9	1.2	0.9
Medication: Co-codamol	1.1	1.3	4.6	2.1	-0.3	1.4	1.4	1.2	-0.8	0.7	1.0	-0.3	1.3	0.8	0.9
Leg fat-free mass (left)	1.1	5.7	9.1	2.1	2.1	2.8	2.5	2.6	2.5	0.9	3.0	2.0	2.5	2.7	2.1
Leg predicted mass (left)	1.1	5.8	9.3	2.1	2.2	2.9	2.5	2.6	2.5	0.9	3.0	2.1	2.5	2.8	2.1
Number of live births	1.1	1.5	3.9	2.0	0.2	0.9	1.6	1.5	-0.0	2.0	1.1	0.2	1.2	0.9	1.0
Noisy workplace	1.1	1.3	3.2	-0.9	-1.3	-1.4	-1.2	-1.8	-0.4	-0.2	-1.5	-1.1	-0.8	-1.2	-1.0
Chronic bronchitis/emphysema (mother)	1.1	1.3	4.7	1.1	1.1	0.9	1.0	0.5	0.4	1.1	1.3	1.0	1.2	1.2	2.2
Mouth/teeth dental problems: Loose teeth	1.1	1.3	2.3	0.7	1.2	1.4	0.8	0.4	-0.7	0.4	1.5	1.2	1.5	1.4	1.5
Stomach or abdominal pain in last month	1.0	1.2	3.7	1.9	1.0	1.2	0.7	0.7	-0.6	0.8	1.5	1.1	1.1	1.2	0.3
Allergy	1.0	2.3	4.1	0.3	1.8	1.3	1.4	1.3	1.9	2.0	0.9	1.7	1.4	1.5	1.7
Serious illness, injury or assault of a close relative in last 2 years	1.0	1.1	2.4	0.8	1.2	1.0	0.8	0.6	1.2	0.5	1.4	1.6	1.0	1.2	1.0
Arm fat mass (right)	1.0	4.3	7.5	1.7	1.7	2.7	2.5	2.0	1.6	1.1	2.0	1.3	2.6	2.5	2.4
Glaucoma (self-reported)	1.0	1.1	4.1	1.0	0.5	0.7	1.3	0.9	1.4	2.0	0.3	0.3	1.3	0.8	1.0
Comparative body size at age 10	1.0	2.8	9.5	0.3	1.5	2.1	1.5	1.9	3.1	-0.0	1.5	1.2	1.7	1.8	0.9
Health satisfaction	1.0	1.3	3.0	0.7	1.7	0.9	0.6	0.8	1.2	0.4	1.2	1.7	0.8	1.2	1.7
Hypertension (Self-reported)	1.0	2.7	10.6	1.5	0.6	1.0	1.8	0.8	1.5	3.3	0.9	0.5	2.0	1.3	2.5
Arm fat mass (left)	1.0	4.2	7.3	1.7	1.8	2.7	2.4	2.0	1.6	1.0	1.9	1.4	2.6	2.5	2.4
Age started oral contraceptive pill	1.0	1.3	2.0	-1.0	-1.4	-1.3	-1.1	-1.1	-0.3	-1.2	-1.4	-1.4	-1.0	-1.4	-0.2
Crohns Disease (2017)	0.9	1.9	5.3	-0.7	-1.5	-1.3	-1.1	-0.8	-1.5	-0.9	-1.2	-1.3	-1.6	-1.5	-2.3
Type 2 Diabetes (T2D) (2012)	0.9	1.0	1.9	1.3	0.4	1.3	1.4	1.4	0.8	0.8	0.9	0.2	1.2	1.0	0.5
Lung FEV1/FVC ratio	0.9	4.6	10.2	0.1	2.7	2.0	1.8	2.1	3.2	0.5	2.6	2.6	1.7	2.4	1.9
Maternal smoking around birth	0.9	1.3	2.2	1.1	1.4	0.8	1.0	0.8	1.2	1.5	1.1	1.4	1.1	1.2	1.1
Ever highly irritable/argumentative for 2 days	0.9	1.1	3.0	1.3	0.3	0.7	1.2	0.8	1.7	1.7	0.5	0.6	1.1	0.8	0.6
Whole body fat mass	0.9	3.6	6.2	1.7	1.4	2.4	2.4	1.8	1.2	1.5	1.6	0.9	2.5	2.2	2.3
Leg fat-free mass (right)	0.9	4.9	8.4	1.9	2.2	2.7	2.1	2.4	2.3	0.4	2.9	2.1	2.2	2.6	1.9
Mood swings	0.9	1.6	6.6	2.6	0.1	1.2	1.8	1.1	-0.3	1.5	0.9	0.2	1.5	1.0	0.7
Leg predicted mass (right)	0.9	4.8	8.4	1.9	2.1	2.6	2.1	2.4	2.3	0.4	2.9	2.0	2.1	2.5	1.9
Number of operations (self-reported)	0.9	1.4	3.3	-1.8	0.2	-1.8	-1.0	-1.3	-0.9	-0.6	-1.8	0.2	-1.3	-1.1	0.6
Risk taking	0.9	1.2	4.0	-0.1	-1.0	-1.5	-0.9	-1.2	-2.0	0.3	-1.3	-0.5	-1.0	-1.2	-0.9
Irritable Bowel Disease (IBD)	0.8	1.8	4.0	-0.3	-1.5	-1.0	-0.9	-0.5	-1.7	-1.3	-1.4	-1.7	-1.4	-1.5	-2.0
Neuroticism (2016)	0.8	1.2	3.0	1.7	0.9	1.2	1.0	0.9	0.7	1.1	1.2	1.1	1.0	1.1	0.6
Type 2 Diabetes (T2D) (2018)	0.8	1.5	3.4	0.7	1.3	1.1	1.0	0.9	1.5	0.6	1.5	1.1	1.2	1.4	1.8
Frequency of depressed mood in last 2 weeks	0.8	1.2	4.0	2.0	0.4	1.4	1.3	1.2	-0.3	0.8	1.2	0.2	1.2	1.1	0.2
Waist circumference	0.8	3.1	4.9	1.5	1.4	2.2	2.1	1.8	1.6	1.0	1.6	1.3	2.1	2.0	1.9
Hair/balding pattern: Pattern 2	0.8	1.0	1.6	-0.5	-1.2	-0.9	-0.9	-1.1	-1.3	-1.2	-0.7	-1.3	-0.9	-1.1	-0.4
Qualifications: A levels/AS levels or equivalent	0.8	1.7	5.8	-2.1	-0.3	-1.1	-1.5	-0.6	-0.1	-2.4	-0.6	-0.5	-1.7	-1.2	-1.2
Birth weight of first child	0.8	1.4	2.8	-1.7	-0.9	-1.2	-1.5	-1.4	-0.4	-1.4	-0.6	-0.8	-1.5	-1.2	-0.9
Heart disease (mother)	0.8	1.0	4.8	0.9	0.3	0.1	1.5	0.9	0.6	2.2	0.4	0.3	1.0	0.5	1.0
Supplements: Vitamin C	0.8	1.0	2.5	-0.3	-1.1	-1.2	-0.7	-0.9	-1.6	-0.4	-0.8	-1.3	-1.0	-1.2	0.3
Mouth/teeth dental problems: Mouth ulcers	0.8	1.3	5.1	0.2	-1.7	-0.6	-0.5	-0.9	-2.3	-0.6	-0.5	-1.7	-0.4	-0.8	-1.1
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.8	0.9	1.9	1.1	0.2	1.2	1.2	1.0	0.4	0.9	0.9	-0.0	1.2	0.9	1.4
Cholesterol lowering medication	0.8	1.2	3.8	1.2	1.0	0.9	0.7	0.4	1.1	1.5	0.9	1.0	1.0	1.0	1.9
Prostate Cancer	0.7	0.9	3.2	0.9	0.9	1.1	0.6	0.7	1.8	0.2	0.6	0.9	0.6	0.9	1.4
Waist Hip Ratio (WHR)	0.7	3.3	5.4	-1.2	-2.3	-1.8	-1.6	-1.9	-1.7	-0.8	-2.3	-2.2	-1.5	-2.0	-2.0
Asthma	0.7	1.4	8.2	0.5	-1.5	-0.2	-0.3	-0.4	-2.9	-1.1	-1.0	-1.9	-0.2	-0.8	-0.1
Headache pain in last month	0.7	1.2	2.0	-0.2	-1.4	-1.3	-0.9	-0.7	-0.9	-1.0	-0.8	-1.2	-1.4	-1.4	-1.1
Exposure to tobacco smoke outside home	0.7	0.9	1.5	-1.2	-1.0	-1.1	-0.9	-1.1	-0.6	-0.7	-1.2	-0.7	-1.0	-1.1	-0.5
Emphysema/chronic bronchitis	0.7	0.8	2.2	-0.9	-0.2	-1.0	-1.5	-1.5	0.2	-1.0	-0.3	-0.1	-1.1	-0.7	-0.7
Medication: Ibuprofen	0.7	0.8	1.5	-1.0	-1.2	-0.6	-0.7	-0.9	-0.9	-0.7	-1.0	-1.2	-0.8	-0.9	-0.5
Qualifications: NVQ or HND or HNC or equivalent	0.7	0.9	3.0	1.0	0.6	0.7	1.2	0.6	0.5	1.7	0.5	0.8	1.1	0.9	0.9
Average weekly red wine intake	0.7	1.0	4.2	-1.5	0.5	-0.6	-1.3	-0.4	0.5	-2.0	-0.5	0.6	-1.3	-0.7	-0.8
Vascular/heart problems diagnosed by doctor	0.7	2.0	9.5	-1.2	-0.3	-0.6	-1.4	-0.6	-1.6	-3.1	-0.6	-0.0	-1.6	-0.9	-2.0
Intelligence (Savage-Jansen 2018)	0.6	1.7	5.1	-2.3	0.6	-1.1	-1.8	-0.6	1.0	-2.1	-0.8	0.9	-1.5	-0.8	-0.7
Ulcerative Colitis (UC)	0.6	1.1	2.6	-0.2	-1.2	-0.5	-0.5	-0.0	-1.4	-1.4	-1.2	-1.6	-0.9	-1.1	-1.1
Ever had hysterectomy (womb removed)	0.6	0.7	2.1	0.1	1.3	0.3	0.8	0.5	0.6	0.8	0.4	1.1	0.6	0.8	1.4
Current tobacco smoking	0.6	1.0	3.4	-1.8	-0.2	-1.1	-1.1	-1.4	-1.4	-0.6	-0.4	0.1	-1.1	-0.7	-0.3
Past tobacco smoking	0.6	1.1	4.7	2.2	-1.2	1.0	0.8	0.8	-0.7	0.8	0.6	-1.1	1.3	0.5	-0.6
Arm fat percentage (right)	0.6	2.4	4.7	1.2	1.2	2.2	2.1	1.6	1.0	0.8	1.1	0.7	2.1	1.9	1.8
Breastfed as a baby	0.6	0.7	2.4	1.1	0.4	1.5	0.4	0.8	-0.7	-0.0	1.3	0.4	0.9	0.9	-0.5
Hypothyroidism/myxoedema (self-reported)	0.6	1.2	1.8	1.1	0.7	1.3	1.0	1.1	0.8	1.1	1.3	0.8	1.3	1.2	1.2
High blood pressure (siblings)	0.6	0.9	3.8	0.3	1.2	0.4	0.6	0.3	0.7	2.0	0.1	1.2	0.7	0.8	1.5
Qualifications: College or University degree	0.6	1.8	14.3	-1.3	0.6	0.0	-1.2	0.6	0.3	-3.8	0.5	0.6	-1.4	-0.4	-1.0
Medication for pain relief, constipation, heartburn	0.6	1.1	5.3	-1.4	0.1	-0.8	-1.5	-0.4	-0.2	-2.3	-0.0	-0.1	-1.3	-0.7	-0.7
Knee pain experienced in last month	0.6	0.9	2.6	1.6	0.5	1.0	1.0	0.5	-0.8	1.0	1.2	0.5	1.1	1.0	0.8
Arm fat percentage (left)	0.6	2.4	4.6	1.1	1.4	2.2	2.0	1.5	1.0	0.6	1.1	0.9	2.1	1.9	2.0
Handedness (chirality/laterality): Left-handed	0.6	0.8	3.1	0.5	-1.7	-0.0	-0.2	-0.5	-1.3	0.3	-0.1	-1.7	0.1	-0.5	-0.6
Medication: Aspirin	0.6	0.8	2.8	1.2	0.5	0.8	1.0	0.6	0.8	1.7	1.0	0.2	1.0	0.9	0.2
Wears glasses or contact lenses	0.6	0.7	3.3	-0.7	1.5	0.7	0.4	0.4	0.7	0.1	0.8	1.8	0.5	0.9	0.3
Verbal and Numeric Reasoning (VNR)	0.5	1.2	4.0	-1.7	0.5	-1.0	-1.5	-0.5	0.1	-2.0	-0.7	0.7	-1.4	-0.7	-0.8
Mean Putamen Volume	0.5	0.6	2.0	-0.7	-1.4	-0.7	-0.6	-1.0	-0.8	0.0	-0.4	-1.2	-0.4	-0.8	0.1
Hypothyroidism (self reported)	0.5	1.1	1.6	1.1	1.2	1.2	0.8	0.9	-0.3	0.9	1.2	0.9	1.2	1.3	1.2
Respiratory disease	0.5	1.1	2.4	1.4	0.6	1.3	1.1	1.4	-1.0	-0.1	0.9	0.6	1.0	0.9	1.5
Angina	0.5	0.6	1.3	-0.8	-0.4	-0.9	-1.0	-1.1	-1.1	-0.3	-0.6	-0.5	-1.0	-0.8	-0.4
Fed-up feelings	0.5	1.0	1.9	1.4	1.2	1.1	1.2	0.7	-0.4	1.3	0.1	1.0	1.1	1.0	0.7
Medication: Atenolol	0.5	0.6	3.9	0.7	-0.8	-0.4	0.4	-0.5	0.8	2.0	-0.8	-0.7	0.5	-0.2	0.3
Angina (self-reported)	0.5	0.6	1.8	-0.7	-0.5	-0.7	-0.9	-1.1	-1.4	-0.4	-0.4	-0.7	-0.8	-0.7	-0.5
Had major operations	0.5	0.5	1.4	0.3	-1.2	-0.7	-0.4	-0.9	-1.0	0.3	-0.8	-1.1	-0.2	-0.7	-0.3
Leg pain on walking	0.5	0.7	1.7	-0.4	-0.6	-0.9	-1.0	-1.3	-1.1	-0.5	-1.0	-0.2	-0.6	-0.8	0.4
Diabetes diagnosed by doctor	0.5	0.7	1.9	0.2	1.2	0.6	0.5	0.3	1.3	0.7	0.7	0.9	0.7	0.9	1.4
Asthma (self-reported)	0.5	1.1	7.5	0.7	-1.2	0.1	-0.0	-0.0	-2.7	-0.7	-0.7	-1.5	0.1	-0.5	0.1
Ever depressed for a whole week	0.5	0.7	2.2	-0.2	1.1	0.3	0.9	1.0	1.1	0.7	0.1	1.5	0.4	0.7	0.0
Bipolar Disorder (2018)	0.4	0.6	2.0	-0.0	-0.9	-0.3	-1.1	-0.4	0.4	-1.4	0.1	-1.0	-0.6	-0.7	-0.9
Alzheimer’s Disease (including proxy)	0.4	0.5	2.4	-0.5	-0.0	-0.7	-0.9	-0.6	-1.6	-0.5	-0.7	0.3	-0.8	-0.5	-0.8
Reaction Time	0.4	0.7	3.3	-1.8	-0.3	-0.9	-0.7	-0.9	0.4	-0.5	-0.8	-0.4	-0.7	-0.7	0.6
Age at First Birth	0.4	0.6	1.7	0.2	-1.2	-0.0	-0.7	-0.4	-1.3	-1.2	-0.4	-0.8	-0.4	-0.6	-0.7
Cardiovascular Disease	0.4	1.3	5.4	1.2	-0.9	0.3	1.2	-0.0	0.7	2.3	0.3	-1.0	1.3	0.5	1.5
Number of treatments/medications taken	0.4	0.7	2.5	0.9	-0.3	-0.0	0.7	-0.1	1.3	1.6	0.6	-0.4	0.7	0.2	1.3
Heel bone mineral density (BMD) T-score, automated (left)	0.4	0.9	1.9	0.4	1.4	0.7	1.0	1.1	1.3	0.2	1.3	1.3	0.5	0.9	0.4
Alcohol usually taken with meals	0.4	0.7	2.3	-1.1	-0.6	-0.1	-1.0	-0.4	-0.1	-1.5	-0.3	-0.7	-0.7	-0.6	-1.3
Ever unenthusiastic/disinterested for a whole week	0.4	0.4	1.1	0.5	0.8	0.5	0.7	0.7	0.0	1.0	-0.2	1.0	0.7	0.6	0.3
Qualifications: None of the above	0.4	0.9	5.0	1.0	0.1	0.6	1.3	0.3	-0.5	2.2	0.2	-0.1	1.2	0.7	1.0
Mouth/teeth dental problems	0.4	0.6	1.7	0.5	1.1	0.7	0.7	1.2	0.7	0.1	0.5	1.3	0.1	0.7	-0.1
Medication: Ramipril	0.4	0.5	1.5	-1.2	-0.5	-1.0	-0.6	-1.0	-0.4	-0.1	-0.8	-0.6	-0.5	-0.7	0.1
Pulse rate	0.4	0.7	1.5	1.2	0.7	0.9	0.9	0.6	-0.4	1.0	0.9	0.7	1.1	1.0	0.3
Medication: Ibuprofen (e.g. Nurofen)	0.4	0.5	2.1	-0.1	-1.2	-0.3	0.1	-0.4	-1.4	0.4	-1.0	-1.0	-0.2	-0.6	-0.5
Medication: Cholesterol lowering	0.4	0.7	3.3	0.7	-0.2	0.4	1.1	0.4	1.3	1.8	0.1	-0.3	0.8	0.4	0.4
Prospective memory result	0.4	0.5	2.5	1.0	-0.4	0.6	0.4	0.3	-1.6	0.2	0.6	-0.5	0.8	0.4	-0.2
Forced expiratory volume in 1-second (FEV1), Best measure	0.4	1.3	2.2	1.1	1.2	1.2	1.2	1.4	1.5	1.1	1.3	0.9	1.1	1.2	0.5
Mouth/teeth dental problems: Bleeding gums	0.4	0.6	2.0	-0.1	-0.8	-0.6	0.3	0.2	-1.4	0.9	-1.0	-1.1	0.1	-0.5	-0.2
Mean time to correctly identify matches	0.4	0.7	2.6	-1.6	-0.3	-0.9	-1.0	-1.2	0.1	-0.8	-0.5	-0.3	-0.9	-0.7	0.3
Alcohol intake frequency.	0.4	0.9	4.4	1.3	-0.4	0.5	1.3	0.3	-0.2	2.1	-0.1	-0.3	1.3	0.5	0.9
Medication: Aspirin	0.4	0.5	2.7	1.1	-0.1	0.5	0.8	0.2	0.2	1.6	0.6	-0.2	0.8	0.5	-0.2
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.4	0.5	1.7	0.6	1.3	0.7	0.3	0.4	0.4	0.3	-0.0	1.2	0.6	0.8	0.9
Long-standing illness, disability or infirmity	0.4	0.6	3.0	1.0	0.6	0.1	0.5	-0.1	-0.8	1.7	0.5	0.8	0.6	0.6	0.8
Back pain experienced in last month	0.4	0.6	3.1	1.7	-0.5	0.3	0.8	0.0	-0.9	1.0	-0.0	-0.6	0.6	0.2	0.3
Osteoporosis (self-reported)	0.4	0.5	1.2	0.9	0.5	0.2	1.1	1.0	-0.5	0.9	0.3	0.6	0.6	0.5	0.3
Illnesses of father: None of the above (group 1)	0.4	0.5	0.9	0.3	0.9	1.0	0.9	0.9	0.5	0.4	-0.5	0.5	0.9	0.8	0.3
Smoking status: Current	0.4	0.7	2.4	-1.6	-0.2	-0.9	-0.8	-1.2	-1.2	-0.4	-0.2	0.1	-0.9	-0.6	-0.1
Medication: Bendroflumethiazide	0.4	0.6	4.4	0.8	-0.4	0.6	0.2	-0.1	2.1	0.7	0.1	-0.7	0.7	0.3	0.5
Ever had prostate specific antigen (PSA) test	0.4	0.5	1.5	-0.9	-0.2	-0.3	-0.7	-0.4	1.2	-0.6	-0.5	-0.5	-0.6	-0.5	-1.2
Myopia	0.4	0.5	2.1	-1.1	1.5	-0.0	-0.0	0.4	-0.3	-0.5	-0.2	1.4	-0.3	0.2	0.6
Deep venous thrombosis (DVT) (self-reported)	0.4	0.5	0.9	-0.9	0.9	-0.2	-0.7	-0.7	0.6	-0.8	0.9	0.9	-0.6	0.2	-0.2
Breast Cancer	0.3	0.6	2.4	-0.9	-0.2	-0.5	-1.0	-0.8	-0.9	-1.5	-0.8	0.2	-0.6	-0.5	0.4
Bipolar Disorder (2011)	0.3	0.2	0.6	0.6	0.8	0.5	-0.2	0.1	0.3	-0.2	0.3	0.8	0.5	0.6	0.5
Rheumatoid Arthritis	0.3	0.4	1.4	0.6	-0.9	0.2	-0.2	-0.6	-1.2	-0.1	0.1	-0.9	0.2	-0.2	-0.7
Triglycerides	0.3	0.4	1.0	-0.4	-0.5	-0.6	-0.8	-0.5	-1.0	-1.0	-0.2	-0.2	-0.9	-0.6	-0.5
Ulcerative Colitis	0.3	0.4	1.6	0.8	-0.9	0.2	0.4	0.4	-0.7	-0.5	-0.7	-1.3	0.2	-0.4	-0.2
Smoking Status	0.3	0.7	2.3	-1.5	1.0	-0.7	-0.7	-0.9	0.6	-0.6	0.5	1.2	-0.9	-0.1	0.7
Tanning	0.3	3.7	11.4	1.0	2.4	1.0	1.2	1.1	2.5	3.4	1.7	2.1	1.7	1.8	1.7
Relative age of first facial hair	0.3	0.5	1.8	-0.2	0.9	-0.1	0.5	0.8	-0.0	1.2	-0.2	1.4	0.1	0.4	1.1
Systolic blood pressure, automated reading	0.3	0.8	3.1	0.8	-0.4	0.5	0.8	0.1	1.1	1.8	0.1	-0.5	1.1	0.4	1.4
Vitamin and mineral supplements	0.3	0.5	1.6	1.0	0.1	0.8	0.6	0.6	-0.1	1.3	0.3	0.2	1.0	0.7	-0.0
Diabetes (mother)	0.3	0.4	1.0	0.3	-0.8	-0.8	-0.1	-0.6	-1.0	0.6	-0.5	-0.9	-0.1	-0.7	0.5
Pack years adult smoking proportion	0.3	0.4	1.4	0.2	1.2	1.0	-0.0	0.4	0.3	-0.8	0.5	0.8	0.2	0.7	-0.2
Bilateral oophorectomy (both ovaries removed)	0.3	0.3	1.2	0.7	-0.6	-0.2	0.2	-0.4	-0.8	0.6	-0.4	-1.1	0.0	-0.3	0.1
Serious illness, injury or assault to yourself	0.3	0.4	1.3	0.6	1.0	0.3	0.2	0.1	0.8	0.7	0.5	1.2	0.3	0.7	0.3
Supplements: Glucosamine	0.3	0.4	1.5	0.1	-0.7	-0.2	-0.5	-0.4	0.5	-1.2	-0.5	-0.8	-0.6	-0.6	-0.0
Trunk fat mass	0.3	1.5	3.1	1.1	0.7	1.7	1.6	1.1	0.5	0.6	1.0	0.2	1.8	1.4	1.7
Number of incorrect matches in round	0.3	0.5	2.5	0.6	-0.3	0.1	0.4	-0.1	1.5	1.6	0.3	-0.4	0.6	0.3	0.4
Heart attack	0.3	0.4	1.4	0.1	0.9	-0.1	0.6	0.5	-0.0	1.2	-0.7	0.8	0.2	0.2	0.6
Medication: Simvastatin	0.3	0.4	2.9	0.2	-0.2	0.0	0.3	-0.1	1.7	0.8	0.1	-0.5	0.2	-0.0	1.2
Pulse wave reflection index	0.3	0.3	1.2	-0.1	1.1	0.3	0.4	0.2	-0.1	0.6	0.4	1.0	0.2	0.5	0.8
Blood clot in the leg (DVT)	0.3	0.3	0.9	-0.7	0.7	-0.2	-0.5	-0.6	0.7	-0.5	0.9	0.8	-0.5	0.2	0.1
Medication for cholesterol, blood pressure or diabetes	0.3	0.5	2.8	-0.4	0.5	-0.2	-0.9	-0.4	-1.2	-1.7	-0.3	0.2	-0.6	-0.3	-0.4
Body fat percentage	0.3	1.3	3.0	1.0	0.5	1.5	1.6	1.0	0.3	1.0	0.5	0.0	1.7	1.3	1.7
Reason for reducing amount of alcohol drunk: Health precaution	0.3	0.4	1.8	0.4	0.3	0.6	-0.1	0.4	1.4	-0.7	0.5	0.4	0.2	0.3	-0.8
Pulse wave peak to peak time	0.3	0.3	1.0	-0.1	-0.9	0.1	0.0	0.4	-0.3	-0.5	-0.7	-1.0	-0.0	-0.4	-0.9
Chest pain or discomfort	0.3	0.4	1.1	1.1	0.7	0.6	0.4	0.6	-0.7	0.1	0.8	0.5	0.5	0.6	0.4
Family relationship satisfaction	0.3	0.3	1.8	-0.5	-0.2	-0.6	-0.3	0.1	1.3	-0.0	-0.6	0.4	-0.7	-0.5	-0.1
Illness, injury, bereavement, stress in last 2 years	0.3	0.4	1.6	0.0	-1.2	0.0	-0.4	0.0	-0.9	-0.2	-0.2	-1.3	-0.2	-0.6	-0.5
Illnesses of siblings: Diabetes	0.3	0.4	1.9	0.3	0.2	0.2	0.7	0.2	-0.3	1.4	0.0	0.5	0.8	0.4	0.9
Smoking status: Previous	0.3	0.4	1.3	-1.1	0.8	-0.5	-0.4	-0.4	0.6	-0.6	-0.4	0.6	-0.8	-0.2	0.5
Ever had stillbirth, spontaneous miscarriage or termination	0.3	0.3	1.0	-0.9	1.0	-0.6	-0.3	-0.2	-0.2	-0.0	0.0	1.0	-0.6	-0.1	-0.0
Friendships satisfaction	0.3	0.4	1.6	-0.3	1.2	-0.0	-0.0	0.6	0.8	-0.3	-0.1	1.3	-0.3	0.3	0.3
Eye problems/disorders: Cataract	0.3	0.4	1.1	0.9	0.2	0.4	0.5	0.4	1.1	0.6	1.0	0.5	0.4	0.4	0.2
Medication for cholesterol	0.3	0.4	1.5	-0.5	0.2	0.1	-0.1	0.5	-1.2	-1.1	0.1	0.6	-0.3	-0.1	-1.1
Financial situation satisfaction	0.3	0.3	0.9	-0.4	0.5	0.4	0.7	0.8	0.6	-0.0	0.5	0.9	0.3	0.4	0.8
Eye problems/disorders: Glaucoma	0.3	0.3	1.8	0.3	-0.5	-0.3	0.3	0.1	0.9	1.4	-0.3	-0.5	0.3	-0.2	-0.2
High cholesterol (Self-reported)	0.3	0.5	1.8	0.8	-0.1	0.5	1.0	0.5	0.9	1.4	0.4	-0.3	0.8	0.5	0.9
Fractured/broken bones in last 5 years	0.3	0.4	2.1	1.0	0.0	0.4	0.3	0.5	-1.5	0.5	-0.4	0.0	0.3	0.1	0.3
Commuting to job workplace: Cycle	0.3	0.4	1.5	-0.7	-0.2	-0.4	-0.9	-0.6	0.0	-1.2	-0.4	-0.5	-0.6	-0.4	-0.3
Supplements: Calcium	0.3	0.4	1.8	0.0	-0.6	-0.2	-0.3	-0.1	0.2	-1.4	-0.4	-0.8	-0.5	-0.6	-0.7
Alzheimer’s Disease (in mother)	0.2	0.2	1.2	0.2	0.9	0.1	-0.0	0.2	-0.7	0.2	-0.1	1.1	-0.1	0.3	-0.3
Major Depression (MDD)	0.2	0.2	1.2	-0.3	0.5	0.3	-0.1	0.2	-1.1	-0.0	0.7	0.7	-0.1	0.3	-0.3
Ovarian Cancer	0.2	0.3	1.6	-0.8	-0.4	0.1	-0.5	-0.4	-0.6	-1.3	0.1	-0.1	-0.2	-0.1	-0.3
Coronary Artery Disease (CAD)	0.2	0.3	0.8	0.9	-0.5	0.4	0.9	0.4	-0.5	0.6	-0.1	-0.5	0.5	0.1	0.1
HDL Cholesterol	0.2	0.3	0.8	-0.3	-0.2	-0.8	-0.8	-0.9	-0.2	-0.5	-0.6	0.1	-0.8	-0.6	-0.4
Blood Eosinophil Count	0.2	1.5	4.3	-0.7	-2.1	-0.7	-0.7	-1.2	-1.2	-0.7	-1.2	-1.9	-0.8	-1.3	-1.1
Blood Platelet Count	0.2	2.2	3.5	-1.4	-1.8	-1.5	-1.5	-1.6	-0.5	-1.1	-1.5	-1.9	-1.4	-1.6	-1.7
Height	0.2	4.1	6.8	-2.1	-2.6	-2.5	-2.4	-2.1	-0.6	-0.8	-1.6	-2.3	-2.2	-2.5	-1.2
Systolic Blood Pressure	0.2	1.1	6.8	1.2	-1.3	-0.1	0.5	-0.4	0.6	2.6	-0.3	-1.2	0.9	-0.1	0.9
Eye problems/disorders: Diabetes related eye disease	0.2	0.2	0.5	-0.3	-0.2	-0.1	-0.6	-0.3	0.7	-0.6	-0.3	-0.3	-0.4	-0.2	-0.3
Supplements: Zinc	0.2	0.2	1.9	-0.1	-0.2	-0.2	-0.1	-0.4	-1.4	-0.6	0.1	-0.1	-0.2	-0.3	-0.0
Diabetes (father)	0.2	0.2	0.9	0.5	-0.2	0.5	0.0	0.5	-0.2	-0.9	0.9	-0.4	0.0	0.1	-0.2
Relative age voice broke	0.2	0.3	0.8	0.5	0.8	0.1	0.5	0.9	-0.3	0.5	0.1	0.8	0.2	0.4	0.4
Qualifications: CSEs or equivalent	0.2	0.3	1.2	1.1	-0.6	0.1	0.8	-0.2	0.4	0.5	-0.1	-0.6	0.4	0.1	0.7
Multivitamins +/- minerals	0.2	0.3	1.5	-0.5	0.8	0.1	0.3	0.3	1.2	-0.3	0.4	0.5	0.0	0.3	0.6
Sitting height	0.2	1.7	2.9	1.4	0.8	1.4	1.2	1.4	1.1	1.1	1.7	0.9	1.3	1.3	1.5
Forced vital capacity (FVC)	0.2	0.6	1.8	-0.8	-0.6	-1.0	-0.6	-0.5	0.5	-0.4	-0.5	-0.6	-1.1	-1.0	-1.3
Diabetes (self-reported)	0.2	0.2	0.8	-0.6	0.6	-0.3	-0.3	-0.5	0.9	0.0	0.2	0.3	-0.2	0.1	0.8
Hayfever/allergic rhinitis (self-reported)	0.2	0.2	0.6	0.6	0.3	0.7	0.3	0.3	0.2	0.2	0.8	0.5	0.6	0.6	0.5
Fluid intelligence score	0.2	0.4	1.9	-0.7	0.3	-0.4	-0.9	-0.0	0.6	-1.4	-0.5	0.4	-0.6	-0.4	-0.8
Time employed in main current job	0.2	0.3	1.0	-0.1	0.7	0.1	-0.3	-0.3	0.8	-0.8	0.6	1.0	-0.1	0.2	0.3
Alcohol intake versus 10 years previously	0.2	0.2	0.9	0.9	-0.5	0.1	0.6	-0.2	-0.0	0.7	-0.3	-0.6	0.6	0.1	0.4
Father’s age at death	0.2	0.3	1.1	-0.7	0.7	-0.2	-0.5	0.0	0.1	-0.5	0.2	1.0	-0.5	0.0	-0.6
Hair/balding pattern: Pattern 3	0.2	0.3	1.1	0.4	-0.0	0.6	1.0	1.0	-0.2	1.0	-0.0	0.0	0.6	0.4	0.2
Mouth/teeth dental problems: Dentures	0.2	0.4	0.9	-0.8	-0.1	-0.6	-0.7	-0.9	0.9	-0.5	0.1	-0.2	-0.3	-0.3	1.0
Pulse wave Arterial Stiffness index	0.2	0.2	0.6	-0.2	0.6	-0.4	-0.2	-0.6	0.2	0.3	0.5	0.8	-0.3	0.1	0.7
Standing height	0.2	2.0	3.0	-1.2	-1.7	-1.7	-1.5	-1.1	-0.3	-1.2	-1.0	-1.5	-1.7	-1.7	-1.5
Peak expiratory flow (PEF)	0.2	0.5	2.3	0.1	0.5	0.5	1.1	1.1	1.5	0.5	0.2	0.6	0.4	0.5	0.0
Qualifications: O levels/GCSEs or equivalent	0.2	0.3	0.5	-0.7	0.6	-0.5	-0.7	-0.6	-0.5	-0.5	-0.1	0.7	-0.5	-0.2	-0.2
Medication: Paracetamol	0.2	0.4	1.2	1.1	-0.7	0.5	0.8	-0.1	0.0	0.9	-0.5	-0.4	0.9	0.2	0.3
Wheeze or whistling in the chest in last year	0.2	0.4	2.5	0.9	0.1	-0.1	0.4	0.4	-1.6	0.6	-0.6	-0.1	0.1	-0.1	0.2
Age at first live birth	0.2	0.3	1.2	0.1	-0.5	0.2	-0.1	0.3	-1.1	-0.6	1.1	0.1	0.0	0.1	-0.9
Shortness of breath walking on level ground	0.2	0.2	1.7	0.1	0.6	-0.0	-0.1	-0.3	-0.2	0.4	0.0	0.6	0.1	0.3	1.3
Medication: Blood pressure	0.2	0.3	2.6	0.4	-0.6	0.1	0.5	0.2	0.0	1.6	0.3	-0.5	0.5	0.1	-0.1
Medication: Allopurinol	0.2	0.3	2.1	0.1	-0.3	0.5	0.1	0.1	-1.5	0.4	0.2	-0.3	0.5	0.3	-0.8
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.2	0.2	0.6	-0.6	0.8	-0.3	0.1	0.0	-0.1	0.7	-0.4	0.7	-0.1	0.1	0.5
Overall health rating	0.2	0.3	1.4	0.9	0.2	0.4	0.4	-0.1	-1.2	0.6	-0.1	0.2	0.6	0.4	0.7
Age at last live birth	0.2	0.4	1.5	0.2	-0.2	0.3	-0.2	0.3	-1.2	-0.4	1.2	0.3	0.0	0.2	-0.9
Illnesses of father: Heart disease	0.2	0.3	1.3	0.6	-0.3	0.2	0.4	0.4	0.5	0.3	1.2	-0.1	0.4	0.3	0.6
Qualifications: nursing, teaching	0.2	0.3	1.0	0.1	0.2	0.4	0.2	0.7	1.0	-0.7	1.0	0.8	-0.1	0.3	0.1
Number of self-reported non-cancer illnesses	0.2	0.3	1.2	1.1	0.1	0.1	0.7	-0.0	-0.5	1.1	0.2	0.0	0.7	0.3	0.6
Average weekly champagne plus white wine intake	0.2	0.3	1.3	-0.4	-0.6	-0.3	-0.3	-0.0	0.1	-0.7	-0.5	-0.7	-0.4	-0.5	-1.2
Hearing aid user	0.2	0.2	1.4	-0.1	-0.2	-0.3	-0.2	-0.7	-1.2	0.2	-0.3	0.0	-0.1	-0.3	-0.1
Mother’s age at death	0.2	0.3	0.8	0.4	0.5	0.5	0.5	0.9	0.8	0.5	0.6	0.6	0.4	0.5	0.0
Average weekly beer plus cider intake	0.2	0.3	1.0	0.4	0.9	-0.0	0.1	0.0	-0.9	0.8	0.1	1.0	0.1	0.4	0.1
Heart attack/myocardial infarction (self-reported)	0.2	0.2	1.1	0.1	0.5	-0.3	0.4	0.4	-0.1	1.1	-0.7	0.3	0.1	0.0	0.4
Heart disease (siblings)	0.2	0.3	2.0	-0.0	-0.2	0.4	0.3	0.1	1.4	-0.2	0.2	-0.2	0.3	0.2	0.7
Pack years of smoking	0.2	0.3	1.0	-0.1	1.0	0.6	-0.2	0.1	0.5	-0.8	0.2	0.7	-0.0	0.4	-0.3
Crohns Disease (2012)	0.1	0.1	0.8	0.9	0.1	0.2	0.3	0.3	0.5	0.5	0.2	0.0	0.1	0.2	-0.2
HbA1C	0.1	0.1	0.6	-0.8	-0.2	-0.1	-0.0	0.2	-0.6	-0.5	-0.1	-0.4	-0.1	-0.3	-0.2
LDL Cholesterol	0.1	0.1	0.5	0.2	0.1	0.1	0.1	0.1	-0.3	0.7	0.6	-0.1	0.4	0.2	0.2
Lupus	0.1	0.1	0.2	-0.1	-0.2	-0.3	-0.3	-0.2	0.3	-0.2	-0.2	0.0	-0.4	-0.4	-0.4
Blood Red Count	0.1	0.6	1.7	0.5	-1.0	-0.2	-0.7	-1.0	-0.9	-0.1	-0.8	-1.3	-0.0	-0.5	-0.8
Lung FVC	0.1	0.7	3.4	0.2	-0.9	0.0	-0.5	-0.2	-0.0	-1.4	0.3	-0.8	-0.6	-0.6	-1.8
Hand grip strength (left)	0.1	0.1	0.7	0.5	0.2	0.0	-0.2	-0.1	-0.3	0.3	0.8	0.5	-0.0	0.2	-0.4
Ever used hormone-replacement therapy (HRT)	0.1	0.1	0.5	0.3	-0.1	0.4	0.4	0.2	0.5	-0.3	-0.5	-0.2	0.3	0.0	0.7
Medication: Metformin	0.1	0.2	1.1	0.1	0.2	0.1	0.1	-0.0	1.0	0.7	0.4	-0.1	0.3	0.3	0.6
Severe depression (siblings)	0.1	0.1	0.7	-0.2	0.8	0.1	-0.1	0.1	0.1	-0.4	0.6	0.5	-0.2	0.3	-0.0
Trunk fat percentage	0.1	0.4	1.1	0.3	-0.2	0.9	0.8	0.3	-0.6	0.1	-0.1	-0.7	1.0	0.5	1.0
Hand grip strength (right)	0.1	0.1	0.3	0.5	0.0	-0.1	-0.5	-0.3	-0.5	-0.3	0.5	0.3	-0.2	-0.0	-0.6
Average weekly fortified wine intake	0.1	0.1	0.3	0.5	0.3	0.1	0.1	0.1	-0.3	0.5	0.1	0.4	0.3	0.1	0.4
Age when periods started (menarche)	0.1	0.3	1.2	0.5	0.4	-0.2	0.3	0.4	-0.9	0.7	0.2	1.1	0.0	0.2	-0.6
Medication: Levothyroxine sodium	0.1	0.1	0.6	0.3	-0.7	0.1	-0.1	-0.3	-0.8	0.2	0.1	-0.4	0.2	-0.1	0.5
Hearing difficulty/problems with background noise	0.1	0.2	1.1	-0.2	0.9	0.4	0.2	0.4	-0.1	0.1	0.5	1.1	-0.1	0.4	-0.3
Heel bone mineral density (BMD) T-score, automated (right)	0.1	0.2	0.8	-0.1	0.8	0.0	0.1	0.3	0.9	0.0	0.3	0.7	-0.1	0.1	-0.4
Forced expiratory volume in 1-second (FEV1)	0.1	0.4	2.6	0.3	0.5	0.2	0.6	0.8	1.6	0.6	0.5	0.5	0.2	0.3	-0.2
Medication: Lansoprazole	0.1	0.1	0.4	0.6	0.4	-0.2	0.3	0.1	-0.1	0.5	-0.5	0.4	-0.0	0.0	0.3
Gout (self-reported)	0.1	0.1	0.6	0.0	0.1	0.6	0.2	0.4	-0.8	0.3	0.3	-0.1	0.4	0.4	-0.3
Medication: Amlodipine	0.1	0.1	0.3	-0.2	0.0	-0.1	-0.1	-0.0	-0.4	0.5	0.4	0.4	0.1	0.1	0.3
Medication: Ventolin 100micrograms inhaler	0.1	0.1	0.5	0.2	-0.3	0.3	0.2	-0.1	0.4	-0.3	-0.1	-0.7	0.1	0.0	0.3
Birth weight	0.1	0.2	0.6	0.6	0.2	0.1	0.8	0.5	0.2	0.6	-0.0	-0.2	0.2	0.1	0.2
Forced vital capacity (FVC), Best measure	0.1	0.3	0.9	0.7	0.2	0.3	0.4	0.6	1.0	0.5	0.7	0.0	0.2	0.3	-0.4
Worry too long after embarrassment	0.1	0.2	0.5	0.3	0.7	0.1	-0.3	-0.3	-0.1	-0.7	0.6	0.7	-0.1	0.3	-0.0
Eye problems/disorders: None of the above	0.1	0.2	1.2	-0.3	0.4	0.1	-0.1	-0.0	-1.1	-0.4	-0.1	0.4	-0.1	0.1	-0.1
Neck or shoulder pain in last month	0.1	0.1	0.8	0.6	-0.1	0.0	0.1	-0.3	-0.1	-0.1	0.9	0.4	0.0	0.2	-0.0
Migraine (self-reported)	0.1	0.1	0.5	0.4	0.3	0.1	0.3	0.3	0.7	-0.5	0.3	0.3	-0.0	0.2	-0.4
Comparative height size at age 10	0.1	0.3	1.1	0.4	-1.0	0.2	0.2	0.6	0.1	-0.8	0.0	-1.0	-0.2	-0.4	-0.6
Ever had bowel cancer screening	0.1	0.1	0.5	0.7	-0.4	0.1	-0.1	-0.1	-0.4	-0.2	-0.2	-0.4	-0.0	-0.2	-0.1
Osteoarthritis (self-reported)	0.1	0.1	0.4	0.4	0.3	0.2	-0.0	-0.1	-0.3	-0.1	0.1	0.7	0.1	0.1	-0.2
Ever taken oral contraceptive pill	0.1	0.1	0.6	0.0	-0.3	0.2	0.0	-0.3	-0.8	-0.2	0.0	-0.5	0.2	0.1	0.4
Medication: Paracetamol	0.1	0.1	0.3	0.5	-0.2	0.2	0.5	-0.1	0.5	0.3	-0.3	-0.0	0.5	0.2	0.5
Diastolic blood pressure, automated reading	0.1	0.4	2.1	0.4	-1.1	0.3	0.5	-0.3	0.2	0.3	-0.3	-1.4	0.5	-0.0	0.9
Basal cell carcinoma (self-reported)	0.1	0.2	0.7	0.4	-0.2	0.6	0.4	0.7	0.8	-0.1	0.3	-0.2	0.2	0.2	-0.3
Fasting Glucose	0.0	0.0	0.1	-0.2	0.1	-0.0	-0.2	-0.3	0.3	0.0	0.0	0.3	-0.0	-0.0	0.3
Blood White Count	0.0	0.4	0.8	0.9	0.2	0.9	0.3	0.0	0.3	0.6	0.5	0.4	0.9	0.7	0.7
Heel T-Score	0.0	0.2	0.7	-0.7	0.6	-0.1	-0.2	-0.2	0.8	-0.7	0.1	0.3	-0.2	0.0	0.4
Hair Pigment	0.0	0.7	3.3	-0.1	-1.0	-0.6	-0.4	-1.0	-1.8	-0.2	-0.5	-1.0	-0.6	-0.9	0.3
Forced expiratory volume in 1-second (FEV1), predicted	0.0	0.1	0.2	-0.4	0.5	-0.3	0.0	0.2	0.4	0.2	-0.0	0.2	-0.1	0.0	0.1

Hub : Genes

RNF180

Models

Trait associations