Best TWAS P=2.53e-09 · Best GWAS P=4.58e-10 conditioned to 0.257
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Prostate | ASCC3 | 0.32 | 0.03 | lasso | 6 | 0.06 | 0.0112 | -2.4 | -6.0 | 2.5e-09 | 0.52 | 0.07 | 0.25 | TRUE |
| 2 | ROSMAP | Brain Pre-frontal Cortex | RP3-467N11.1 | 0.02 | 0.00 | blup | 287 | 0.01 | 0.0230 | 5.2 | -5.2 | 1.6e-07 | 0.83 | 0.06 | 0.46 | FALSE |
| 3 | The Cancer Genome Atlas | Esophageal Carcinoma | ASCC3 | 0.11 | 0.07 | blup | 131 | 0.07 | 0.0024 | 4.3 | 5.5 | 2.9e-08 | -0.90 | 0.08 | 0.68 | FALSE |
| 4 | The Cancer Genome Atlas | Thyroid Carcinoma | ASCC3 | 0.06 | 0.05 | lasso | 1 | 0.04 | 0.0002 | -6.0 | 6.0 | 2.6e-09 | -0.94 | 0.06 | 0.92 | TRUE |