Best TWAS P=1.29e-12 · Best GWAS P=1.91e-15 conditioned to 0.00027
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | The Cancer Genome Atlas | Kidney Renal Papillary Cell Carcinoma | MMP16 | 0.1 | 0.08 | blup | 131 | 0.05 | 1.3e-03 | 7.4 | 6.1 | 8.5e-10 | 0.79 | 0.03 | 0.95 | FALSE |
2 | The Cancer Genome Atlas | Thyroid Carcinoma | MMP16 | 0.1 | 0.09 | lasso | 4 | 0.08 | 2.9e-08 | 7.5 | 7.1 | 1.3e-12 | 0.84 | 0.04 | 0.96 | TRUE |