Best TWAS P=1.1e-09 · Best GWAS P=7.46e-10 conditioned to 0.0405
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Colon Sigmoid | UBXN2B | 0.16 | 0.01 | lasso | 6 | 0.04 | 2.1e-02 | -5.2 | -5.5 | 5.2e-08 | 0.69 | 0.15 | 0.58 | FALSE |
| 2 | GTEx | Heart Atrial Appendage | SDCBP | 0.19 | 0.17 | lasso | 3 | 0.15 | 2.7e-07 | -5.5 | 6.1 | 1.1e-09 | -0.82 | 0.06 | 0.93 | TRUE |