[Hub]/) : Traits : Impedance of arm (left) :

chr9:126,321,003-127,872,298

Best TWAS P=4.37e-16 · Best GWAS P=3.52e-17 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex PSMB7 0.05 0.01 lasso 3 0.03 3.1e-04 -7.1 6.7 2.1e-11 -0.61 0.24 0.19 FALSE
2 GTEx Adipose Subcutaneous PSMB7 0.08 0.04 lasso 6 0.04 3.4e-04 -5.9 7.6 2.8e-14 -0.84 0.02 0.98 FALSE
3 GTEx Artery Aorta PSMB7 0.15 0.03 enet 16 0.05 1.4e-03 6.3 6.4 1.4e-10 -0.55 0.12 0.45 FALSE
4 GTEx Artery Tibial PSMB7 0.07 0.04 enet 7 0.03 4.1e-03 -5.9 6.0 1.9e-09 -0.66 0.47 0.18 FALSE
5 GTEx Breast Mammary Tissue PSMB7 0.11 0.03 lasso 7 0.04 4.7e-03 -8.4 8.1 4.4e-16 -0.98 0.00 0.98 TRUE
6 GTEx Cells Transformed fibroblasts PSMB7 0.09 0.07 enet 11 0.06 2.1e-05 6.3 6.8 1.3e-11 -0.78 0.30 0.68 FALSE
7 GTEx Colon Sigmoid PSMB7 0.15 0.10 lasso 3 0.09 3.3e-04 -6.6 6.9 7.3e-12 -0.76 0.12 0.76 FALSE
8 GTEx Colon Transverse PSMB7 0.13 0.02 lasso 3 0.03 1.8e-02 -8.4 7.2 4.3e-13 -0.90 0.00 0.97 FALSE
9 GTEx Nerve Tibial NEK6 0.11 0.02 enet 40 0.03 3.9e-03 -6.8 5.6 1.8e-08 -0.37 0.08 0.40 FALSE
10 GTEx Thyroid NEK6 0.20 0.21 lasso 4 0.20 1.3e-15 -6.5 7.0 2.0e-12 -0.78 0.72 0.28 FALSE
11 GTEx Thyroid PSMB7 0.06 0.04 lasso 2 0.06 4.1e-05 -6.1 7.0 3.3e-12 -0.77 0.03 0.96 FALSE
12 The Cancer Genome Atlas Breast Invasive Carcinoma NEK6 0.04 0.02 blup 87 0.02 2.5e-05 6.8 5.7 1.0e-08 -0.37 0.79 0.13 FALSE
13 The Cancer Genome Atlas Colon Adenocarcinoma LOC100129034 0.12 0.00 lasso 4 0.04 1.7e-03 -7.4 -5.5 3.1e-08 0.59 0.02 0.35 FALSE
14 The Cancer Genome Atlas Prostate Adenocarcinoma NEK6 0.06 0.01 blup 87 0.04 1.0e-04 6.8 6.8 1.4e-11 -0.51 0.18 0.45 FALSE
15 The Cancer Genome Atlas Prostate Adenocarcinoma PSMB7 0.03 0.04 lasso 4 0.04 1.2e-04 -7.1 7.3 3.1e-13 -0.78 0.04 0.91 FALSE
16 The Cancer Genome Atlas Thyroid Carcinoma PSMB7 0.06 0.06 lasso 4 0.04 3.7e-05 -7.2 7.2 5.7e-13 -0.84 0.08 0.92 FALSE