[Hub]/) : Traits : Impedance of arm (left) : ← →

chr9:126,321,003-127,872,298

Best TWAS P=4.37e-16 · Best GWAS P=3.52e-17 conditioned to 1

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
5	GTEx	Breast Mammary Tissue	PSMB7	0.11	0.03	lasso	7	0.04	4.7e-03	-8.4	8.1	4.4e-16	-0.98	0.00	0.98	TRUE
2	GTEx	Adipose Subcutaneous	PSMB7	0.08	0.04	lasso	6	0.04	3.4e-04	-5.9	7.6	2.8e-14	-0.84	0.02	0.98	FALSE
15	The Cancer Genome Atlas	Prostate Adenocarcinoma	PSMB7	0.03	0.04	lasso	4	0.04	1.2e-04	-7.1	7.3	3.1e-13	-0.78	0.04	0.91	FALSE
8	GTEx	Colon Transverse	PSMB7	0.13	0.02	lasso	3	0.03	1.8e-02	-8.4	7.2	4.3e-13	-0.90	0.00	0.97	FALSE
16	The Cancer Genome Atlas	Thyroid Carcinoma	PSMB7	0.06	0.06	lasso	4	0.04	3.7e-05	-7.2	7.2	5.7e-13	-0.84	0.08	0.92	FALSE
10	GTEx	Thyroid	NEK6	0.20	0.21	lasso	4	0.20	1.3e-15	-6.5	7.0	2.0e-12	-0.78	0.72	0.28	FALSE
11	GTEx	Thyroid	PSMB7	0.06	0.04	lasso	2	0.06	4.1e-05	-6.1	7.0	3.3e-12	-0.77	0.03	0.96	FALSE
7	GTEx	Colon Sigmoid	PSMB7	0.15	0.10	lasso	3	0.09	3.3e-04	-6.6	6.9	7.3e-12	-0.76	0.12	0.76	FALSE
6	GTEx	Cells Transformed fibroblasts	PSMB7	0.09	0.07	enet	11	0.06	2.1e-05	6.3	6.8	1.3e-11	-0.78	0.30	0.68	FALSE
14	The Cancer Genome Atlas	Prostate Adenocarcinoma	NEK6	0.06	0.01	blup	87	0.04	1.0e-04	6.8	6.8	1.4e-11	-0.51	0.18	0.45	FALSE
1	CommonMind	Brain Pre-frontal Cortex	PSMB7	0.05	0.01	lasso	3	0.03	3.1e-04	-7.1	6.7	2.1e-11	-0.61	0.24	0.19	FALSE
3	GTEx	Artery Aorta	PSMB7	0.15	0.03	enet	16	0.05	1.4e-03	6.3	6.4	1.4e-10	-0.55	0.12	0.45	FALSE
4	GTEx	Artery Tibial	PSMB7	0.07	0.04	enet	7	0.03	4.1e-03	-5.9	6.0	1.9e-09	-0.66	0.47	0.18	FALSE
12	The Cancer Genome Atlas	Breast Invasive Carcinoma	NEK6	0.04	0.02	blup	87	0.02	2.5e-05	6.8	5.7	1.0e-08	-0.37	0.79	0.13	FALSE
9	GTEx	Nerve Tibial	NEK6	0.11	0.02	enet	40	0.03	3.9e-03	-6.8	5.6	1.8e-08	-0.37	0.08	0.40	FALSE
13	The Cancer Genome Atlas	Colon Adenocarcinoma	LOC100129034	0.12	0.00	lasso	4	0.04	1.7e-03	-7.4	-5.5	3.1e-08	0.59	0.02	0.35	FALSE