Best TWAS P=2.04e-10 · Best GWAS P=9.49e-12 conditioned to 0.13
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Aorta | ORAOV1 | 0.13 | 0.07 | lasso | 3 | 0.04 | 2.0e-03 | -5.5 | -6.0 | 1.8e-09 | -0.10 | 0.12 | 0.55 | TRUE |
| 2 | GTEx | Breast Mammary Tissue | IGHMBP2 | 0.49 | 0.47 | enet | 28 | 0.50 | 8.1e-29 | -4.2 | -5.3 | 1.4e-07 | -0.23 | 1.00 | 0.00 | FALSE |
| 3 | ROSMAP | Brain Pre-frontal Cortex | PPP6R3 | 0.04 | 0.01 | blup | 421 | 0.02 | 3.2e-04 | 6.7 | -5.7 | 1.0e-08 | -0.86 | 0.03 | 0.96 | FALSE |
| 4 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | SAPS3 | 0.04 | 0.02 | blup | 84 | 0.04 | 2.5e-05 | 5.6 | -6.4 | 2.0e-10 | -0.86 | 0.07 | 0.92 | TRUE |