Best TWAS P=1.77e-09 · Best GWAS P=7.21e-09 conditioned to 0.0412
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | PRSS23 | 0.14 | 0.13 | lasso | 8 | 0.13 | 4.7e-16 | -4.3 | -5.6 | 2.6e-08 | 0.72 | 0.78 | 0.21 | FALSE |
| 2 | GTEx | Artery Tibial | ME3 | 0.24 | 0.06 | lasso | 8 | 0.11 | 4.1e-09 | -3.4 | 5.9 | 3.3e-09 | -0.57 | 0.02 | 0.98 | FALSE |
| 3 | GTEx | Thyroid | PRSS23 | 0.18 | 0.09 | lasso | 9 | 0.14 | 1.2e-10 | -4.4 | -6.0 | 1.8e-09 | 0.73 | 0.37 | 0.62 | TRUE |