Best TWAS P=2.09e-08 · Best GWAS P=1.15e-07 conditioned to 0.551
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Artery Aorta | ARHGDIB | 0.10 | 0.06 | enet | 10 | 0.08 | 5.4e-05 | 5.2 | -5.2 | 1.6e-07 | -0.98 | 0.02 | 0.98 | FALSE |
2 | GTEx | Lung | MGP | 0.11 | 0.00 | enet | 19 | 0.02 | 2.3e-02 | 4.4 | -5.3 | 9.4e-08 | -0.56 | 0.04 | 0.72 | FALSE |
3 | YFS | Blood | ERP27 | 0.30 | 0.41 | enet | 31 | 0.42 | 3.1e-152 | 4.9 | -5.1 | 2.6e-07 | -0.96 | 0.05 | 0.94 | FALSE |
4 | The Cancer Genome Atlas | Breast Invasive Carcinoma | ERP27 | 0.04 | 0.09 | lasso | 5 | 0.09 | 2.8e-17 | 5.2 | -5.2 | 1.7e-07 | -0.97 | 0.01 | 0.99 | FALSE |
5 | The Cancer Genome Atlas | Cervical Squamous Cell Carcinoma | ERP27 | 0.09 | 0.14 | lasso | 2 | 0.12 | 1.7e-06 | 5.3 | -5.3 | 1.1e-07 | -1.00 | 0.01 | 0.98 | FALSE |
6 | The Cancer Genome Atlas | Esophageal Carcinoma | ERP27 | 0.10 | 0.12 | blup | 75 | 0.08 | 1.5e-03 | 4.9 | -5.4 | 6.7e-08 | -0.93 | 0.02 | 0.89 | FALSE |
7 | The Cancer Genome Atlas | Glioblastoma Multiforme | ERP27 | 0.18 | 0.07 | blup | 76 | 0.11 | 2.7e-04 | 5.2 | -5.2 | 2.5e-07 | -0.88 | 0.02 | 0.92 | FALSE |
8 | The Cancer Genome Atlas | Head and Neck Squamous Cell Carcinoma | ERP27 | 0.10 | 0.18 | lasso | 6 | 0.18 | 1.2e-19 | 5.3 | -5.2 | 2.3e-07 | -0.98 | 0.02 | 0.98 | FALSE |
9 | The Cancer Genome Atlas | Lung Adenocarcinoma | ERP27 | 0.15 | 0.28 | lasso | 6 | 0.28 | 8.3e-33 | 5.3 | -5.3 | 9.4e-08 | -0.99 | 0.01 | 0.99 | FALSE |
10 | The Cancer Genome Atlas | Lung Squamous Cell Carcinoma | ERP27 | 0.17 | 0.24 | enet | 13 | 0.25 | 6.7e-28 | 5.1 | -5.3 | 1.2e-07 | -0.98 | 0.02 | 0.98 | FALSE |
11 | The Cancer Genome Atlas | Pheochromocytoma and Paraganglioma | ERP27 | 0.14 | 0.12 | lasso | 5 | 0.11 | 2.9e-05 | 5.2 | -5.3 | 1.2e-07 | -0.97 | 0.01 | 0.98 | FALSE |
12 | The Cancer Genome Atlas | Skin Cutaneous Melanoma | ERP27 | 0.13 | 0.02 | blup | 74 | 0.06 | 1.4e-02 | 5.3 | -5.6 | 2.1e-08 | -0.90 | 0.02 | 0.76 | TRUE |
13 | The Cancer Genome Atlas | Testicular Germ Cell Tumors | ERP27 | 0.10 | 0.05 | lasso | 1 | 0.08 | 8.9e-04 | 5.2 | -5.2 | 1.5e-07 | -0.97 | 0.02 | 0.96 | FALSE |