Best TWAS P=2.96e-20 · Best GWAS P=4.38e-19 conditioned to 0.0518
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | METSIM | Adipose | SLC38A2 | 0.02 | 0.02 | blup | 341 | 0.01 | 0.00581 | 8.1 | -7.6 | 3.6e-14 | -0.90 | 0.06 | 0.90 | FALSE |
2 | The Cancer Genome Atlas | Kidney Renal Papillary Cell Carcinoma | SLC38A2 | 0.10 | 0.06 | blup | 30 | 0.05 | 0.00083 | 8.8 | -9.2 | 3.0e-20 | -0.86 | 0.01 | 0.91 | TRUE |
3 | The Cancer Genome Atlas | Soft Tissue Sarcoma | SLC38A2 | 0.06 | 0.01 | blup | 30 | 0.03 | 0.00513 | 8.9 | -7.1 | 1.6e-12 | -0.92 | 0.02 | 0.74 | FALSE |