[Hub]/) : Traits : Impedance of arm (left) :

chr14:90,643,934-94,495,324

Best TWAS P=8.5e-12 · Best GWAS P=7.7e-12 conditioned to 3.97e-05

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex BTBD7 0.04 0.04 lasso 2 0.03 1.8e-04 5.7 -5.8 5.2e-09 0.05 0.07 0.92 TRUE
2 GTEx Cells Transformed fibroblasts BTBD7 0.16 0.01 lasso 8 0.04 3.6e-04 5.7 -5.6 2.6e-08 -0.01 0.08 0.91 FALSE
3 GTEx Cells Transformed fibroblasts RPS6KA5 0.08 0.07 lasso 2 0.06 5.3e-05 6.7 -6.8 8.5e-12 0.03 0.01 0.99 TRUE
4 GTEx Colon Sigmoid RIN3 0.24 0.17 lasso 6 0.11 9.3e-05 -6.7 6.8 1.0e-11 0.28 0.02 0.96 TRUE
5 GTEx Colon Sigmoid RPS6KA5 0.16 0.09 lasso 5 0.08 7.1e-04 6.1 6.2 6.8e-10 -0.01 0.06 0.85 FALSE
6 GTEx Esophagus Muscularis RIN3 0.17 0.05 lasso 6 0.06 1.6e-04 -5.6 6.0 1.5e-09 0.39 0.09 0.65 FALSE
7 GTEx Spleen C14orf159 0.30 0.21 lasso 5 0.21 3.6e-06 5.3 -6.0 1.9e-09 0.01 0.08 0.36 FALSE
8 NTR Blood BTBD7 0.02 0.03 lasso 2 0.02 6.1e-08 5.7 -5.8 5.2e-09 0.05 0.08 0.92 FALSE
9 The Cancer Genome Atlas Lung Adenocarcinoma RIN3 0.05 0.00 blup 163 0.01 6.0e-02 3.0 5.8 8.0e-09 0.33 0.02 0.18 TRUE
10 The Cancer Genome Atlas Lung Squamous Cell Carcinoma BTBD7 0.02 0.01 blup 72 0.02 6.8e-03 5.8 -5.8 8.1e-09 -0.08 0.01 0.87 FALSE
11 The Cancer Genome Atlas Testicular Germ Cell Tumors BTBD7 0.11 0.03 blup 72 0.02 8.0e-02 5.7 -5.6 1.6e-08 -0.05 0.02 0.72 FALSE
12 The Cancer Genome Atlas Thyroid Carcinoma TRIP11 0.08 0.04 blup 70 0.06 3.6e-06 -3.7 -5.2 2.2e-07 0.04 0.12 0.81 TRUE