[Hub]/) : Traits : Impedance of arm (left) : ← →

chr14:90,643,934-94,495,324

Best TWAS P=8.5e-12 · Best GWAS P=7.7e-12 conditioned to 3.97e-05

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
3	GTEx	Cells Transformed fibroblasts	RPS6KA5	0.08	0.07	lasso	2	0.06	5.3e-05	6.7	-6.8	8.5e-12	0.03	0.01	0.99	TRUE
4	GTEx	Colon Sigmoid	RIN3	0.24	0.17	lasso	6	0.11	9.3e-05	-6.7	6.8	1.0e-11	0.28	0.02	0.96	TRUE
1	CommonMind	Brain Pre-frontal Cortex	BTBD7	0.04	0.04	lasso	2	0.03	1.8e-04	5.7	-5.8	5.2e-09	0.05	0.07	0.92	TRUE
9	The Cancer Genome Atlas	Lung Adenocarcinoma	RIN3	0.05	0.00	blup	163	0.01	6.0e-02	3.0	5.8	8.0e-09	0.33	0.02	0.18	TRUE
12	The Cancer Genome Atlas	Thyroid Carcinoma	TRIP11	0.08	0.04	blup	70	0.06	3.6e-06	-3.7	-5.2	2.2e-07	0.04	0.12	0.81	TRUE
5	GTEx	Colon Sigmoid	RPS6KA5	0.16	0.09	lasso	5	0.08	7.1e-04	6.1	6.2	6.8e-10	-0.01	0.06	0.85	FALSE
6	GTEx	Esophagus Muscularis	RIN3	0.17	0.05	lasso	6	0.06	1.6e-04	-5.6	6.0	1.5e-09	0.39	0.09	0.65	FALSE
7	GTEx	Spleen	C14orf159	0.30	0.21	lasso	5	0.21	3.6e-06	5.3	-6.0	1.9e-09	0.01	0.08	0.36	FALSE
8	NTR	Blood	BTBD7	0.02	0.03	lasso	2	0.02	6.1e-08	5.7	-5.8	5.2e-09	0.05	0.08	0.92	FALSE
10	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	BTBD7	0.02	0.01	blup	72	0.02	6.8e-03	5.8	-5.8	8.1e-09	-0.08	0.01	0.87	FALSE
11	The Cancer Genome Atlas	Testicular Germ Cell Tumors	BTBD7	0.11	0.03	blup	72	0.02	8.0e-02	5.7	-5.6	1.6e-08	-0.05	0.02	0.72	FALSE
2	GTEx	Cells Transformed fibroblasts	BTBD7	0.16	0.01	lasso	8	0.04	3.6e-04	5.7	-5.6	2.6e-08	-0.01	0.08	0.91	FALSE