[Hub]/) : Traits : Impedance of arm (left) :

chr1:201,158,976-202,607,593

Best TWAS P=9.67e-17 · Best GWAS P=2.37e-17 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous SHISA4 0.09 0.04 lasso 3 0.03 1.5e-03 5.51 6.4 1.6e-10 -0.57 0.21 0.30 FALSE
2 GTEx Esophagus Muscularis LMOD1 0.16 0.09 enet 9 0.08 7.8e-06 -8.42 8.1 7.6e-16 -0.98 0.01 0.99 FALSE
3 GTEx Esophagus Muscularis RP11-307B6.3 0.20 0.12 lasso 3 0.12 5.6e-08 -8.42 8.0 1.9e-15 -0.97 0.01 0.99 FALSE
4 METSIM Adipose LMOD1 0.09 0.07 bslmm 496 0.07 4.8e-10 -8.44 8.3 9.7e-17 -0.97 0.01 0.99 TRUE
5 The Cancer Genome Atlas Bladder Urothelial Carcinoma SHISA4 0.03 0.01 enet 5 0.00 2.5e-01 6.86 5.8 7.9e-09 -0.55 0.04 0.16 FALSE
6 The Cancer Genome Atlas Breast Invasive Carcinoma LMOD1 0.02 0.01 blup 59 0.02 1.2e-04 -8.47 6.8 7.8e-12 -0.86 0.01 0.97 FALSE
7 The Cancer Genome Atlas Cervical Squamous Cell Carcinoma LMOD1 0.07 0.06 blup 59 0.03 2.1e-02 -8.42 7.7 1.1e-14 -0.90 0.01 0.87 FALSE
8 The Cancer Genome Atlas Brain Lower Grade Glioma LMOD1 0.04 0.07 enet 6 0.05 9.4e-07 6.86 7.6 2.2e-14 -0.75 0.23 0.76 FALSE
9 The Cancer Genome Atlas Lung Adenocarcinoma LMOD1 0.04 0.01 blup 59 0.01 5.7e-02 -8.30 7.3 3.1e-13 -0.84 0.01 0.83 FALSE
10 The Cancer Genome Atlas Pancreatic Adenocarcinoma LMOD1 0.08 -0.01 blup 59 0.01 1.3e-01 0.27 6.0 1.7e-09 -0.78 0.01 0.47 FALSE