TWAS
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Traits
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Traits
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Impedance of arm (left)
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chr1:177,282,200-180,018,254
Best TWAS P=2.46e-08 · Best GWAS P=1.63e-26 conditioned to 6.81e-23
177.5M
178M
178.5M
179M
179.5M
180M
0
5
10
15
20
25
physical position
-log10 P
Conditional
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
3
GTEx
Skin Sun Exposed Lower leg
RP11-568K15.1
0.11
0.05
enet
20
0.04
1.3e-04
-4.3
5.6
2.5e-08
-0.38
0.57
0.11
TRUE
2
GTEx
Adrenal Gland
SOAT1
0.16
0.23
lasso
3
0.25
1.7e-09
-5.6
-5.6
2.7e-08
-0.10
0.00
1.00
TRUE
1
CommonMind
Brain Pre-frontal Cortex
LOC730102
0.18
0.12
lasso
9
0.12
1.4e-14
-4.3
5.2
2.0e-07
-0.31
1.00
0.00
FALSE
4
The Cancer Genome Atlas
Skin Cutaneous Melanoma
SOAT1
0.23
0.06
blup
78
0.06
9.2e-03
2.5
5.2
2.1e-07
0.06
0.01
0.21
FALSE