Best TWAS P=2.46e-08 · Best GWAS P=1.63e-26 conditioned to 6.81e-23
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | LOC730102 | 0.18 | 0.12 | lasso | 9 | 0.12 | 1.4e-14 | -4.3 | 5.2 | 2.0e-07 | -0.31 | 1.00 | 0.00 | FALSE |
| 2 | GTEx | Adrenal Gland | SOAT1 | 0.16 | 0.23 | lasso | 3 | 0.25 | 1.7e-09 | -5.6 | -5.6 | 2.7e-08 | -0.10 | 0.00 | 1.00 | TRUE |
| 3 | GTEx | Skin Sun Exposed Lower leg | RP11-568K15.1 | 0.11 | 0.05 | enet | 20 | 0.04 | 1.3e-04 | -4.3 | 5.6 | 2.5e-08 | -0.38 | 0.57 | 0.11 | TRUE |
| 4 | The Cancer Genome Atlas | Skin Cutaneous Melanoma | SOAT1 | 0.23 | 0.06 | blup | 78 | 0.06 | 9.2e-03 | 2.5 | 5.2 | 2.1e-07 | 0.06 | 0.01 | 0.21 | FALSE |