[Hub]/) : Traits : Impedance of arm (left) : ← →

chr20:19,173,950-21,919,054

Best TWAS P=1.42e-12 · Best GWAS P=2.27e-13 conditioned to 1

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
3	GTEx	Artery Tibial	PLK1S1	0.07	0.08	enet	10	0.08	4.0e-07	-7.0	-7.1	1.4e-12	0.97	0.03	0.97	TRUE
2	GTEx	Artery Aorta	RIN2	0.14	0.01	enet	18	0.01	8.5e-02	2.7	-5.1	2.9e-07	-0.05	0.09	0.14	TRUE
8	GTEx	Whole Blood	PLK1S1	0.08	0.04	enet	9	0.02	4.0e-03	-6.2	-6.8	1.2e-11	0.92	0.05	0.95	FALSE
10	The Cancer Genome Atlas	Lung Adenocarcinoma	PLK1S1	0.04	0.03	blup	64	0.04	4.0e-05	-6.2	-6.7	2.5e-11	0.93	0.07	0.92	FALSE
11	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	PLK1S1	0.09	0.02	blup	64	0.05	3.1e-03	-5.7	-6.6	5.2e-11	0.80	0.02	0.61	FALSE
9	The Cancer Genome Atlas	Breast Invasive Carcinoma	PLK1S1	0.05	0.07	enet	9	0.07	5.5e-15	-6.0	-6.3	2.9e-10	0.93	0.12	0.88	FALSE
7	GTEx	Testis	PLK1S1	0.64	0.34	enet	33	0.39	1.0e-18	-6.2	-6.3	4.0e-10	0.81	0.75	0.25	FALSE
13	The Cancer Genome Atlas	Thyroid Carcinoma	PLK1S1	0.06	0.04	lasso	3	0.04	1.5e-04	-6.2	-6.3	4.0e-10	0.90	0.11	0.70	FALSE
5	GTEx	Skin Not Sun Exposed Suprapubic	PLK1S1	0.21	0.09	lasso	6	0.12	5.3e-07	-6.9	-6.2	6.5e-10	0.96	0.07	0.93	FALSE
4	GTEx	Esophagus Mucosa	PLK1S1	0.11	0.11	lasso	5	0.09	7.8e-07	-6.1	-6.1	1.4e-09	0.88	0.07	0.93	FALSE
12	The Cancer Genome Atlas	Prostate Adenocarcinoma	PLK1S1	0.19	0.12	enet	14	0.13	4.3e-13	-6.2	-5.9	2.7e-09	0.82	0.69	0.31	FALSE
1	CommonMind	Brain Pre-frontal Cortex	PLK1S1	0.08	0.01	lasso	3	0.04	1.1e-05	-5.7	-5.8	5.4e-09	0.80	0.03	0.97	FALSE
6	GTEx	Skin Sun Exposed Lower leg	PLK1S1	0.15	0.13	enet	10	0.15	3.9e-12	-6.2	-5.8	6.0e-09	0.87	0.71	0.29	FALSE