TWAS
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Genes
Traits
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Traits
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Impedance of arm (left)
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chr20:61,667,526-62,912,463
Best TWAS P=7.83e-10 · Best GWAS P=4.2e-09 conditioned to 7.15e-05
61.6M
61.8M
62M
62.2M
62.4M
62.6M
62.8M
0
2
4
6
8
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
CommonMind
Brain Pre-frontal Cortex
LIME1
0.04
0.00
bslmm
439
0.01
3.3e-02
3.6
-6.1
7.8e-10
0.35
0.05
0.81
TRUE
3
The Cancer Genome Atlas
Kidney Renal Clear Cell Carcinoma
LIME1
0.04
0.03
lasso
3
0.02
7.2e-04
-5.5
-5.7
9.8e-09
0.19
0.00
0.95
FALSE
2
YFS
Blood
SLC2A4RG
0.03
0.02
lasso
11
0.02
4.2e-08
-5.5
-5.1
2.8e-07
0.15
0.02
0.98
FALSE