Best TWAS P=1.8e-09 · Best GWAS P=3.45e-07 conditioned to 0.0321
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Tibial | AC006547.14 | 0.09 | 0.00 | lasso | 4 | 0.00 | 6.9e-01 | -4.7 | 6.0 | 1.8e-09 | 0.55 | 0.02 | 0.30 | TRUE |
| 2 | GTEx | Cells Transformed fibroblasts | ZDHHC8 | 0.18 | 0.07 | enet | 26 | 0.14 | 8.9e-11 | 4.2 | 5.2 | 2.3e-07 | 0.32 | 0.18 | 0.71 | FALSE |
| 3 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | ARVCF | 0.04 | 0.00 | blup | 116 | 0.00 | 1.8e-01 | -4.7 | 5.2 | 1.9e-07 | 0.53 | 0.02 | 0.32 | FALSE |