TWAS
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Models
Genes
Traits
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Traits
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Impedance of arm (left)
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chr2:202,200,575-203,894,227
Best TWAS P=7.6e-10 · Best GWAS P=4.78e-10 conditioned to 1
202.2M
202.4M
202.6M
202.8M
203M
203.2M
203.4M
203.6M
203.8M
0
2
4
6
8
physical position
-log10 P
Conditional
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
3
The Cancer Genome Atlas
Kidney Renal Papillary Cell Carcinoma
FZD7
0.09
0.11
lasso
3
0.09
5.1e-06
6.2
6.2
7.6e-10
1.00
0.01
0.99
TRUE
1
GTEx
Brain Cerebellar Hemisphere
RP11-107N15.1
0.26
0.02
enet
19
0.07
8.2e-03
1.6
5.5
4.1e-08
0.66
0.02
0.86
FALSE
4
The Cancer Genome Atlas
Thyroid Carcinoma
FZD7
0.04
0.00
blup
62
0.02
8.6e-03
6.1
5.3
1.2e-07
0.88
0.01
0.92
FALSE
2
METSIM
Adipose
RP11-686O6.1
0.02
0.01
bslmm
339
0.01
1.2e-02
4.5
-5.3
1.5e-07
-0.43
0.07
0.12
FALSE