Best TWAS P=7.6e-10 · Best GWAS P=4.78e-10 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Brain Cerebellar Hemisphere | RP11-107N15.1 | 0.26 | 0.02 | enet | 19 | 0.07 | 8.2e-03 | 1.6 | 5.5 | 4.1e-08 | 0.66 | 0.02 | 0.86 | FALSE |
| 2 | METSIM | Adipose | RP11-686O6.1 | 0.02 | 0.01 | bslmm | 339 | 0.01 | 1.2e-02 | 4.5 | -5.3 | 1.5e-07 | -0.43 | 0.07 | 0.12 | FALSE |
| 3 | The Cancer Genome Atlas | Kidney Renal Papillary Cell Carcinoma | FZD7 | 0.09 | 0.11 | lasso | 3 | 0.09 | 5.1e-06 | 6.2 | 6.2 | 7.6e-10 | 1.00 | 0.01 | 0.99 | TRUE |
| 4 | The Cancer Genome Atlas | Thyroid Carcinoma | FZD7 | 0.04 | 0.00 | blup | 62 | 0.02 | 8.6e-03 | 6.1 | 5.3 | 1.2e-07 | 0.88 | 0.01 | 0.92 | FALSE |