[Hub]/) : Traits : Impedance of arm (left) : ← →

chr2:205,851,076-207,874,372

Best TWAS P=6.33e-16 · Best GWAS P=2.1e-16 conditioned to 0.0316

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
2	CommonMind	Brain Pre-frontal Cortex	NDUFS1	0.10	0.09	lasso	9	0.09	1.2e-10	7.2	-8.1	6.3e-16	-0.90	0.05	0.95	TRUE
32	GTEx	Nerve Tibial	AC007383.4	0.14	0.06	lasso	6	0.05	3.0e-04	7.5	-8.0	1.0e-15	-0.83	0.26	0.72	FALSE
20	GTEx	Esophagus Gastroesophageal Junction	NDUFS1	0.16	0.09	enet	22	0.03	2.4e-02	7.2	-7.9	2.1e-15	-0.74	0.11	0.80	FALSE
18	GTEx	Colon Sigmoid	AC007383.4	0.15	0.14	enet	13	0.09	3.8e-04	7.2	-7.8	5.7e-15	-0.82	0.20	0.72	FALSE
22	GTEx	Esophagus Mucosa	NDUFS1	0.09	0.05	lasso	2	0.02	8.6e-03	7.4	-7.8	7.4e-15	-0.78	0.20	0.69	FALSE
34	GTEx	Testis	NDUFS1	0.15	0.08	lasso	6	0.08	2.1e-04	7.0	-7.6	4.0e-14	-0.71	0.08	0.83	FALSE
16	GTEx	Cells Transformed fibroblasts	NDUFS1	0.33	0.42	enet	28	0.40	3.2e-32	6.9	-7.4	1.1e-13	-0.81	0.71	0.29	FALSE
13	GTEx	Brain Putamen basal ganglia	NDUFS1	0.16	0.06	enet	6	0.05	2.9e-02	6.3	-7.4	1.8e-13	-0.76	0.10	0.33	FALSE
27	GTEx	Heart Left Ventricle	AC007383.4	0.17	0.13	enet	19	0.16	9.7e-09	7.2	-7.3	2.2e-13	-0.73	0.68	0.32	FALSE
17	GTEx	Cells Transformed fibroblasts	AC007383.4	0.18	0.15	enet	28	0.17	4.5e-13	6.9	-7.3	2.5e-13	-0.72	0.72	0.28	FALSE
38	ROSMAP	Brain Pre-frontal Cortex	INO80D	0.22	0.34	lasso	2	0.35	2.0e-47	6.7	7.3	3.5e-13	0.90	0.47	0.53	FALSE
25	GTEx	Esophagus Muscularis	AC007383.4	0.10	0.13	enet	4	0.10	1.3e-06	7.2	-7.2	6.9e-13	-0.78	0.50	0.50	FALSE
7	GTEx	Artery Tibial	NDUFS1	0.16	0.15	enet	14	0.15	3.9e-12	6.9	-7.2	8.8e-13	-0.78	0.77	0.23	FALSE
21	GTEx	Esophagus Gastroesophageal Junction	AC007383.4	0.21	0.17	enet	11	0.14	8.5e-06	7.1	-7.1	1.1e-12	-0.78	0.35	0.55	FALSE
24	GTEx	Esophagus Muscularis	NDUFS1	0.17	0.19	enet	21	0.18	5.1e-11	7.2	-7.1	1.1e-12	-0.73	0.66	0.34	FALSE
26	GTEx	Heart Atrial Appendage	AC007383.4	0.12	0.10	enet	21	0.09	9.8e-05	7.5	-7.1	1.3e-12	-0.70	0.57	0.42	FALSE
29	GTEx	Muscle Skeletal	NDUFS1	0.20	0.14	enet	20	0.12	4.0e-12	7.2	-7.0	2.1e-12	-0.77	0.80	0.20	FALSE
3	GTEx	Adipose Subcutaneous	NDUFS1	0.08	0.05	lasso	5	0.01	2.0e-02	6.6	-7.0	2.7e-12	-0.78	0.56	0.33	FALSE
10	GTEx	Brain Cerebellum	AC007383.4	0.23	0.05	lasso	3	0.18	3.9e-06	8.1	-7.0	2.8e-12	-0.77	0.02	0.91	FALSE
42	The Cancer Genome Atlas	Thyroid Carcinoma	GPR1	0.05	0.04	lasso	3	0.04	1.7e-04	7.0	-7.0	3.0e-12	-0.70	0.28	0.17	FALSE
36	METSIM	Adipose	NDUFS1	0.12	0.18	lasso	4	0.17	5.2e-25	6.9	-7.0	3.5e-12	-0.78	0.72	0.28	FALSE
41	The Cancer Genome Atlas	Brain Lower Grade Glioma	NDUFS1	0.05	0.03	blup	51	0.04	6.2e-05	7.5	-7.0	3.6e-12	-0.75	0.49	0.48	FALSE
31	GTEx	Nerve Tibial	NDUFS1	0.13	0.08	enet	14	0.05	3.1e-04	6.2	-6.9	4.8e-12	-0.72	0.78	0.19	FALSE
19	GTEx	Colon Transverse	AC007383.4	0.14	0.09	lasso	2	0.06	8.8e-04	6.6	-6.8	1.1e-11	-0.75	0.17	0.45	FALSE
6	GTEx	Artery Aorta	NDUFS1	0.11	0.07	enet	29	0.01	6.7e-02	7.5	-6.6	3.4e-11	-0.76	0.14	0.76	FALSE
28	GTEx	Liver	AC007383.4	0.27	0.10	lasso	4	0.03	4.4e-02	6.3	-6.5	5.8e-11	-0.69	0.06	0.49	FALSE
37	METSIM	Adipose	ZDBF2	0.03	0.00	bslmm	436	0.00	1.1e-01	-4.7	6.5	6.1e-11	0.64	0.42	0.26	FALSE
30	GTEx	Muscle Skeletal	AC007383.4	0.23	0.18	enet	38	0.20	2.1e-19	7.2	-6.5	1.1e-10	-0.75	0.87	0.13	FALSE
15	GTEx	Breast Mammary Tissue (Female)	AC007362.1	0.46	-0.01	lasso	14	0.00	4.6e-01	6.7	6.4	1.3e-10	0.65	0.04	0.57	FALSE
12	GTEx	Brain Frontal Cortex BA9	AC007383.4	0.39	0.36	lasso	3	0.35	3.3e-10	6.9	-6.4	1.5e-10	-0.74	0.62	0.38	FALSE
9	GTEx	Brain Cerebellum	NDUFS1	0.13	0.15	lasso	2	0.10	5.3e-04	6.2	-6.3	2.8e-10	-0.73	0.05	0.83	FALSE
4	GTEx	Adipose Subcutaneous	AC007383.4	0.08	0.05	lasso	4	0.04	2.8e-04	6.2	-6.2	4.9e-10	-0.74	0.34	0.58	FALSE
23	GTEx	Esophagus Mucosa	AC007383.4	0.16	0.08	enet	26	0.10	5.8e-07	7.2	-6.1	8.2e-10	-0.67	0.48	0.49	FALSE
11	GTEx	Brain Frontal Cortex BA9	NDUFS1	0.36	0.33	lasso	3	0.32	3.9e-09	6.2	-6.1	9.6e-10	-0.71	0.69	0.30	FALSE
33	GTEx	Pituitary	AC007383.4	0.31	0.05	enet	15	0.04	3.9e-02	6.1	-6.0	1.6e-09	-0.66	0.14	0.12	FALSE
1	CommonMind	Brain Pre-frontal Cortex	INO80D	0.03	0.03	enet	12	0.04	2.8e-05	8.1	5.9	3.1e-09	0.82	0.01	0.99	FALSE
14	GTEx	Breast Mammary Tissue (Female)	NRP2	0.29	0.03	lasso	6	0.06	5.7e-03	6.3	5.9	4.1e-09	0.53	0.06	0.44	FALSE
5	GTEx	Adipose Visceral Omentum	AC007383.4	0.10	0.01	lasso	4	0.02	4.8e-02	4.6	-5.7	1.3e-08	-0.50	0.09	0.24	FALSE
40	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	NDUFS1	0.05	0.05	enet	6	0.06	2.3e-07	7.4	-5.3	1.3e-07	-0.50	0.52	0.47	FALSE
35	GTEx	Thyroid	NDUFS1	0.21	0.10	enet	39	0.05	7.4e-05	7.5	-5.2	2.1e-07	-0.55	0.52	0.48	FALSE
8	GTEx	Artery Tibial	ZDBF2	0.07	0.02	lasso	5	0.02	2.1e-02	5.0	5.1	2.8e-07	0.53	0.57	0.17	FALSE
39	ROSMAP	Brain Pre-frontal Cortex	ZDBF2	0.12	0.11	lasso	2	0.11	8.0e-14	4.9	5.1	2.8e-07	0.48	1.00	0.00	FALSE