Best TWAS P=6.12e-12 · Best GWAS P=2.39e-13 conditioned to 0.00629
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 8 | The Cancer Genome Atlas | Testicular Germ Cell Tumors | VWA5B2 | 0.10 | 0.04 | blup | 51 | 0.04 | 1.8e-02 | -5.8 | 6.9 | 6.1e-12 | 0.37 | 0.03 | 0.33 | TRUE |
| 7 | The Cancer Genome Atlas | Lung Adenocarcinoma | PSMD2 | 0.09 | 0.02 | blup | 50 | 0.05 | 1.2e-06 | 7.3 | -6.7 | 1.5e-11 | -0.78 | 0.00 | 0.99 | TRUE |
| 4 | GTEx | Skin Sun Exposed Lower leg | ABCF3 | 0.13 | 0.08 | lasso | 4 | 0.11 | 1.6e-09 | -5.8 | -6.5 | 9.9e-11 | -0.33 | 0.94 | 0.05 | FALSE |
| 5 | The Cancer Genome Atlas | Colon Adenocarcinoma | ABCF3 | 0.07 | 0.00 | blup | 51 | 0.01 | 4.4e-02 | -5.8 | -5.9 | 3.7e-09 | -0.25 | 0.01 | 0.87 | FALSE |
| 6 | The Cancer Genome Atlas | Liver Hepatocellular Carcinoma | ABCF3 | 0.08 | 0.03 | blup | 51 | 0.06 | 6.1e-04 | -3.2 | -5.8 | 5.4e-09 | -0.22 | 0.02 | 0.68 | FALSE |
| 1 | GTEx | Brain Putamen basal ganglia | ECE2 | 0.38 | 0.03 | enet | 22 | 0.11 | 1.4e-03 | -5.1 | -5.5 | 4.8e-08 | -0.28 | 0.07 | 0.22 | FALSE |
| 2 | GTEx | Esophagus Mucosa | ABCF3 | 0.11 | 0.10 | lasso | 3 | 0.08 | 3.6e-06 | 5.2 | -5.3 | 9.5e-08 | -0.26 | 0.59 | 0.27 | FALSE |
| 3 | GTEx | Skin Not Sun Exposed Suprapubic | ABCF3 | 0.15 | 0.10 | lasso | 4 | 0.11 | 1.1e-06 | -5.8 | -5.2 | 2.1e-07 | -0.22 | 0.75 | 0.07 | FALSE |