[Hub]/) : Traits : Impedance of arm (left) : ← →

chr3:134,986,214-137,368,142

Best TWAS P=1.94e-18 · Best GWAS P=3.04e-18 conditioned to 0.00252

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
3	GTEx	Artery Coronary	SLC35G2	0.16	0.03	lasso	8	0.05	6.4e-03	-8.0	8.8	1.9e-18	-0.78	0.09	0.61	TRUE
20	GTEx	Thyroid	RP11-85F14.5	0.07	0.00	lasso	7	0.01	4.7e-02	5.8	-8.6	7.5e-18	0.54	0.13	0.11	FALSE
21	YFS	Blood	MSL2	0.02	0.04	lasso	2	0.03	9.9e-11	-8.1	8.0	1.0e-15	-0.96	0.03	0.97	FALSE
1	CommonMind	Brain Pre-frontal Cortex	PPP2R3A	0.05	0.02	lasso	4	0.05	7.7e-07	-8.6	-7.3	2.9e-13	0.74	0.03	0.96	FALSE
7	GTEx	Brain Cerebellum	RP11-731C17.2	0.31	0.05	enet	39	0.12	2.3e-04	4.2	-6.8	8.7e-12	0.42	0.34	0.13	FALSE
8	GTEx	Breast Mammary Tissue (Male)	RP11-85F14.5	0.08	0.12	lasso	1	0.06	1.6e-02	-6.8	-6.8	1.2e-11	0.62	0.06	0.27	FALSE
5	GTEx	Brain Cerebellar Hemisphere	RP11-731C17.2	0.16	0.02	enet	24	0.09	3.0e-03	7.5	-6.8	1.5e-11	0.25	0.22	0.05	FALSE
14	GTEx	Muscle Skeletal	RP11-85F14.5	0.10	0.08	lasso	17	0.09	6.3e-09	4.2	-6.7	1.7e-11	0.54	0.82	0.18	FALSE
9	GTEx	Cells Transformed fibroblasts	RP11-85F14.5	0.10	0.08	enet	38	0.09	3.9e-07	4.1	-6.7	2.4e-11	0.48	0.94	0.04	FALSE
18	GTEx	Testis	RP11-85F14.5	0.12	0.03	enet	28	0.02	3.8e-02	3.9	-6.6	4.4e-11	0.51	0.38	0.35	FALSE
23	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	STAG1	0.04	0.02	lasso	3	0.02	4.1e-03	-7.4	6.5	6.9e-11	-0.73	0.14	0.63	FALSE
19	GTEx	Thyroid	PPP2R3A	0.10	0.05	enet	18	0.06	1.3e-05	-5.1	-6.5	7.1e-11	0.76	0.06	0.93	FALSE
15	GTEx	Muscle Skeletal	RP11-731C17.2	0.15	0.12	lasso	16	0.12	3.8e-12	4.2	-6.3	2.5e-10	0.46	1.00	0.00	FALSE
12	GTEx	Esophagus Muscularis	RP11-731C17.2	0.16	0.03	enet	13	0.06	1.1e-04	-3.0	-6.0	1.6e-09	0.66	0.19	0.72	FALSE
17	GTEx	Stomach	PPP2R3A	0.08	0.02	lasso	4	0.05	1.9e-03	-7.4	6.0	2.0e-09	-0.80	0.12	0.78	FALSE
24	The Cancer Genome Atlas	Prostate Adenocarcinoma	PCCB	0.06	0.02	lasso	2	0.03	2.3e-04	-8.4	6.0	2.6e-09	-0.74	0.03	0.94	FALSE
13	GTEx	Lung	RP11-85F14.5	0.07	0.05	lasso	19	0.05	8.8e-05	5.8	-5.9	3.8e-09	0.28	0.95	0.01	FALSE
11	GTEx	Esophagus Mucosa	RP11-85F14.5	0.13	0.10	lasso	3	0.11	5.1e-08	5.8	-5.8	5.5e-09	0.27	1.00	0.00	FALSE
22	YFS	Blood	NCK1	0.01	0.02	enet	4	0.02	2.2e-06	5.8	-5.8	5.5e-09	0.27	0.98	0.00	FALSE
6	GTEx	Brain Cerebellum	PPP2R3A	0.28	-0.01	enet	21	0.04	2.9e-02	-8.1	-5.6	1.7e-08	0.55	0.06	0.51	FALSE
16	GTEx	Skin Sun Exposed Lower leg	RP11-85F14.5	0.04	0.01	enet	9	0.03	2.8e-03	4.0	-5.5	4.8e-08	0.35	0.38	0.16	FALSE
2	GTEx	Adipose Visceral Omentum	PPP2R3A	0.08	0.00	enet	17	0.00	3.0e-01	-7.4	-5.3	1.2e-07	0.68	0.10	0.57	FALSE
4	GTEx	Artery Tibial	PPP2R3A	0.07	0.07	lasso	2	0.05	1.5e-04	-4.8	-5.2	1.9e-07	0.73	0.51	0.17	FALSE
10	GTEx	Esophagus Mucosa	PPP2R3A	0.06	0.06	lasso	3	0.04	9.1e-04	-5.1	-5.1	3.0e-07	0.71	0.41	0.43	FALSE