Best TWAS P=1.13e-07 · Best GWAS P=5.93e-08 conditioned to 2.38e-06
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | METSIM | Adipose | CTSO | 0.06 | 0.03 | enet | 8 | 0.03 | 5.3e-06 | -3.9 | 5.1 | 3.0e-07 | -0.15 | 0.02 | 0.97 | FALSE |
| 2 | ROSMAP | Brain Pre-frontal Cortex | CTSO | 0.03 | 0.06 | lasso | 1 | 0.06 | 2.6e-08 | -5.3 | 5.3 | 1.1e-07 | -0.14 | 0.00 | 1.00 | TRUE |
| 3 | The Cancer Genome Atlas | Kidney Renal Papillary Cell Carcinoma | CTSO | 0.10 | 0.05 | blup | 8 | 0.02 | 1.7e-02 | -5.1 | 5.1 | 3.0e-07 | -0.19 | 0.00 | 0.74 | FALSE |
| 4 | The Cancer Genome Atlas | Lung Squamous Cell Carcinoma | CTSO | 0.08 | 0.05 | lasso | 5 | 0.05 | 3.6e-06 | -5.1 | 5.1 | 2.7e-07 | -0.18 | 0.00 | 1.00 | FALSE |