Best TWAS P=1.41e-07 · Best GWAS P=9.44e-27 conditioned to 6.49e-26
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Breast Mammary Tissue (Female) | SETD9 | 0.21 | 0.12 | lasso | 11 | 0.16 | 1.4e-05 | -5.4 | 5.2 | 1.7e-07 | 0.08 | 0.58 | 0.03 | FALSE |
| 2 | The Cancer Genome Atlas | Lung Adenocarcinoma | MAP3K1 | 0.02 | 0.01 | blup | 83 | 0.01 | 9.1e-03 | -3.4 | -5.3 | 1.4e-07 | -0.04 | 0.02 | 0.74 | TRUE |