[Hub]/) : Traits : Impedance of arm (left) : ← →

chr5:62,764,129-65,866,903

Best TWAS P=3.91e-12 · Best GWAS P=3.8e-17 conditioned to 2.86e-11

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous RNF180 0.04 0.02 lasso 5 0.01 1.0e-01 5.2 -5.2 1.5e-07 -0.09 0.15 0.78 FALSE
2 GTEx Artery Aorta RNF180 0.06 0.00 lasso 2 -0.01 9.5e-01 5.5 -5.5 3.8e-08 -0.09 0.05 0.81 FALSE
3 GTEx Brain Cerebellum TRIM23 0.16 0.09 lasso 6 0.07 4.7e-03 5.1 -5.1 2.8e-07 -0.18 0.18 0.06 FALSE
4 GTEx Breast Mammary Tissue NLN 0.17 0.04 enet 13 0.06 3.6e-04 5.1 5.2 1.7e-07 0.17 0.36 0.04 FALSE
5 GTEx Cells Transformed fibroblasts NLN 0.17 0.03 lasso 9 0.06 2.3e-05 5.1 5.5 4.9e-08 0.10 0.95 0.00 FALSE
6 GTEx Testis RNF180 0.10 0.08 lasso 5 0.06 1.8e-03 5.8 -6.1 1.3e-09 -0.07 0.03 0.95 TRUE
7 GTEx Thyroid RNF180 0.09 0.09 lasso 3 0.10 7.7e-08 5.2 -5.2 1.8e-07 -0.11 0.17 0.83 FALSE
8 METSIM Adipose SGTB 0.03 0.00 bslmm 384 0.01 4.7e-03 -2.8 6.9 3.9e-12 0.22 0.22 0.06 TRUE
9 NTR Blood NLN 0.04 0.03 lasso 3 0.03 3.4e-09 5.1 5.2 2.1e-07 0.19 1.00 0.00 FALSE
10 ROSMAP Brain Pre-frontal Cortex RNF180 0.06 0.06 lasso 5 0.07 2.7e-09 5.5 -5.3 1.2e-07 -0.10 0.06 0.94 FALSE
11 The Cancer Genome Atlas Breast Invasive Carcinoma NLN 0.04 0.02 lasso 7 0.02 3.2e-05 5.0 5.7 1.6e-08 0.14 0.00 0.99 FALSE
12 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma NLN 0.06 0.00 blup 101 0.03 3.8e-04 4.1 5.3 1.2e-07 0.03 0.02 0.84 FALSE
13 The Cancer Genome Atlas Lung Squamous Cell Carcinoma RNF180 0.02 0.02 blup 58 0.02 2.0e-03 5.5 -5.9 3.7e-09 -0.10 0.03 0.72 FALSE