Best TWAS P=6.72e-09 · Best GWAS P=3.84e-08 conditioned to 0.152
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Thyroid | RP11-168A11.4 | 0.16 | 0.04 | lasso | 6 | 0.04 | 0.00038 | -5.2 | 5.8 | 6.7e-09 | -0.80 | 0.01 | 0.98 | TRUE |
2 | The Cancer Genome Atlas | Lung Adenocarcinoma | THBS4 | 0.04 | 0.02 | lasso | 3 | 0.02 | 0.00223 | -5.5 | 5.7 | 1.2e-08 | -0.97 | 0.00 | 0.98 | FALSE |