[Hub]/) : Traits : Impedance of arm (left) :

chr6:33,551,514-36,158,878

Best TWAS P=2.48e-20 · Best GWAS P=1.79e-20 conditioned to 0.000276

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex PACSIN1 0.07 0.01 lasso 6 0.02 1.1e-03 -3.8 -6.5 7.7e-11 0.26 0.32 0.04 FALSE
2 GTEx Brain Frontal Cortex BA9 RPS10 0.21 0.08 lasso 3 0.06 8.6e-03 -7.8 -8.7 3.6e-18 0.87 0.07 0.47 FALSE
3 GTEx Cells EBV-transformed lymphocytes C6orf106 0.20 0.00 lasso 5 0.00 2.7e-01 -5.3 -5.5 4.0e-08 0.09 0.07 0.06 FALSE
4 GTEx Cells Transformed fibroblasts RPS10 0.12 0.05 lasso 4 0.06 4.5e-05 -8.8 -9.2 2.5e-20 0.94 0.01 0.99 TRUE
5 GTEx Esophagus Muscularis NUDT3 0.12 0.00 lasso 7 0.02 3.2e-02 -8.8 8.5 1.4e-17 -0.81 0.03 0.82 FALSE
6 GTEx Muscle Skeletal C6orf106 0.08 0.06 lasso 4 0.06 7.1e-07 -3.9 5.2 1.7e-07 -0.10 0.98 0.00 FALSE
7 GTEx Skin Not Sun Exposed Suprapubic SNRPC 0.18 0.04 enet 37 0.03 1.0e-02 -4.2 5.4 7.8e-08 -0.20 0.23 0.10 TRUE
8 GTEx Spleen UHRF1BP1 0.34 0.21 enet 36 0.17 4.5e-05 -4.3 -5.6 2.6e-08 0.26 0.62 0.04 FALSE
9 GTEx Testis RPS10 0.17 0.11 lasso 1 0.04 5.2e-03 -7.5 -7.5 4.7e-14 0.87 0.08 0.75 FALSE
10 GTEx Uterus UHRF1BP1 0.20 0.03 lasso 4 0.07 1.8e-02 -4.1 -5.5 3.4e-08 0.10 0.10 0.08 FALSE
11 METSIM Adipose C6orf106 0.04 0.02 blup 381 0.02 7.7e-04 -4.7 -5.4 5.3e-08 0.28 0.37 0.16 FALSE
12 ROSMAP Brain Pre-frontal Cortex TEAD3 0.07 0.03 bslmm 421 0.04 5.6e-06 -3.4 6.6 3.5e-11 -0.11 0.15 0.81 TRUE
13 YFS Blood NUDT3 0.12 0.12 lasso 9 0.13 2.5e-40 -7.5 -6.5 8.6e-11 0.83 1.00 0.00 FALSE
14 YFS Blood SNRPC 0.02 0.03 lasso 5 0.02 3.0e-08 -5.3 5.3 1.2e-07 -0.07 1.00 0.00 FALSE