TWAS
hub
About
Usage
Models
Genes
Traits
[Hub]/) :
Traits
:
Impedance of arm (left)
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chr6:44,079,216-46,043,561
Best TWAS P=2.3e-07 · Best GWAS P=1.88e-07 conditioned to 1
44M
44.5M
45M
45.5M
46M
0
2
4
6
physical position
-log10 P
Conditional
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
2
GTEx
Brain Cortex
SUPT3H
0.28
0.01
lasso
7
0.01
2.1e-01
5.2
5.2
2.3e-07
0.98
0.04
0.86
TRUE
3
The Cancer Genome Atlas
Lung Squamous Cell Carcinoma
SUPT3H
0.06
0.05
lasso
3
0.05
3.9e-06
5.2
5.2
2.7e-07
0.99
0.02
0.98
FALSE
1
GTEx
Brain Caudate basal ganglia
SUPT3H
0.22
0.12
lasso
6
0.10
8.1e-04
5.0
5.1
2.9e-07
0.86
0.06
0.81
FALSE