Best TWAS P=2.3e-07 · Best GWAS P=1.88e-07 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Brain Caudate basal ganglia | SUPT3H | 0.22 | 0.12 | lasso | 6 | 0.10 | 8.1e-04 | 5.0 | 5.1 | 2.9e-07 | 0.86 | 0.06 | 0.81 | FALSE |
| 2 | GTEx | Brain Cortex | SUPT3H | 0.28 | 0.01 | lasso | 7 | 0.01 | 2.1e-01 | 5.2 | 5.2 | 2.3e-07 | 0.98 | 0.04 | 0.86 | TRUE |
| 3 | The Cancer Genome Atlas | Lung Squamous Cell Carcinoma | SUPT3H | 0.06 | 0.05 | lasso | 3 | 0.05 | 3.9e-06 | 5.2 | 5.2 | 2.7e-07 | 0.99 | 0.02 | 0.98 | FALSE |