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Traits
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Traits
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Impedance of arm (left)
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chr6:104,478,130-106,283,787
Best TWAS P=1.19e-18 · Best GWAS P=4.46e-29 conditioned to 3.84e-12
104.5M
105M
105.5M
106M
0
5
10
15
20
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30
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
2
CommonMind
Brain Pre-frontal Cortex
LIN28B
0.04
0.04
lasso
9
0.03
3.9e-05
8.96
8.8
1.2e-18
0.74
0.22
0.78
TRUE
1
CommonMind
Brain Pre-frontal Cortex
HACE1
0.14
0.10
enet
28
0.11
8.9e-14
3.51
-5.5
4.4e-08
-0.44
1.00
0.00
FALSE
3
GTEx
Lung
HACE1
0.09
0.00
lasso
4
0.00
6.2e-01
1.01
-5.5
4.9e-08
-0.58
0.05
0.32
FALSE
4
ROSMAP
Brain Pre-frontal Cortex
BVES
0.08
0.00
enet
26
0.05
7.3e-07
0.91
5.2
1.8e-07
0.26
0.15
0.12
FALSE