[Hub]/) : Traits : Impedance of arm (left) :

chr6:125,370,626-128,359,362

Best TWAS P=4.44e-09 · Best GWAS P=2.33e-09 conditioned to 0.651

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex CENPW 0.04 0.06 lasso 10 0.06 2.4e-07 -5.6 5.4 5.3e-08 0.06 0.03 0.97 TRUE
2 CommonMind Brain Pre-frontal Cortex HEY2 0.15 0.20 lasso 10 0.21 6.7e-25 5.5 5.6 2.7e-08 0.16 0.01 0.99 FALSE
3 GTEx Colon Transverse ECHDC1 0.18 0.11 lasso 3 0.15 2.0e-07 4.1 5.4 6.8e-08 0.90 0.01 0.98 TRUE
4 GTEx Skin Sun Exposed Lower leg HINT3 0.08 0.01 lasso 4 0.03 2.0e-03 5.0 5.5 5.0e-08 0.05 0.18 0.28 TRUE
5 GTEx Testis HEY2 0.31 0.17 lasso 5 0.19 7.4e-09 5.7 5.8 8.8e-09 0.17 0.01 0.99 FALSE
6 GTEx Thyroid HEY2 0.22 0.24 lasso 6 0.23 1.0e-17 5.7 5.9 4.4e-09 0.17 0.01 0.99 TRUE
7 ROSMAP Brain Pre-frontal Cortex HEY2 0.10 0.12 enet 15 0.13 9.8e-17 -5.5 5.3 9.6e-08 0.15 0.01 0.99 FALSE
8 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma CENPW 0.04 0.05 lasso 5 0.05 2.6e-06 -5.5 5.1 2.8e-07 0.06 0.02 0.98 FALSE
9 The Cancer Genome Atlas Brain Lower Grade Glioma CENPW 0.04 0.06 blup 35 0.05 9.2e-07 -5.3 5.4 5.5e-08 0.05 0.03 0.97 FALSE
10 The Cancer Genome Atlas Thyroid Carcinoma HEY2 0.03 0.04 lasso 3 0.02 3.8e-03 -5.1 5.2 1.7e-07 0.16 0.02 0.97 FALSE