Best TWAS P=3.64e-09 · Best GWAS P=1.73e-09 conditioned to 0.0281
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | DPY19L1 | 0.08 | 0.05 | enet | 11 | 0.06 | 4.4e-08 | -5.2 | -5.9 | 3.6e-09 | 0.79 | 0.19 | 0.81 | TRUE |
| 2 | GTEx | Skin Not Sun Exposed Suprapubic | DPY19L1 | 0.12 | 0.01 | lasso | 8 | 0.05 | 9.5e-04 | -6.0 | 5.7 | 1.4e-08 | -0.93 | 0.01 | 0.98 | FALSE |
| 3 | GTEx | Skin Sun Exposed Lower leg | DPY19L1 | 0.15 | 0.07 | lasso | 7 | 0.05 | 5.7e-05 | -5.7 | 5.8 | 7.9e-09 | -0.97 | 0.01 | 0.99 | FALSE |
| 4 | ROSMAP | Brain Pre-frontal Cortex | DPY19L1 | 0.06 | 0.07 | lasso | 2 | 0.06 | 8.1e-08 | -5.2 | -5.2 | 2.3e-07 | 0.65 | 0.33 | 0.67 | FALSE |
| 5 | The Cancer Genome Atlas | Ovarian Serous Cystadenocarcinoma | DPY19L1 | 0.07 | 0.02 | blup | 62 | 0.03 | 3.8e-03 | -5.8 | 5.2 | 1.7e-07 | -0.89 | 0.01 | 0.90 | FALSE |