TWAS
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Traits
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Traits
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Impedance of arm (left)
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chr7:27,082,425-28,568,019
Best TWAS P=1.17e-11 · Best GWAS P=5.12e-13 conditioned to 2.7e-07
27M
27.2M
27.4M
27.6M
27.8M
28M
28.2M
28.4M
28.6M
0
2
4
6
8
10
12
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
3
The Cancer Genome Atlas
Thyroid Carcinoma
JAZF1
0.12
0.09
lasso
4
0.09
2.1e-09
6.5
6.8
1.2e-11
0.84
0.02
0.98
TRUE
2
The Cancer Genome Atlas
Breast Invasive Carcinoma
JAZF1
0.04
0.02
blup
224
0.03
3.8e-06
3.8
5.4
7.3e-08
0.49
0.57
0.27
TRUE
1
ROSMAP
Brain Pre-frontal Cortex
TAX1BP1
0.10
0.03
bslmm
515
0.07
8.3e-09
-3.8
5.3
1.1e-07
0.03
0.99
0.00
TRUE