Best TWAS P=1.17e-11 · Best GWAS P=5.12e-13 conditioned to 2.7e-07
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | ROSMAP | Brain Pre-frontal Cortex | TAX1BP1 | 0.10 | 0.03 | bslmm | 515 | 0.07 | 8.3e-09 | -3.8 | 5.3 | 1.1e-07 | 0.03 | 0.99 | 0.00 | TRUE |
| 2 | The Cancer Genome Atlas | Breast Invasive Carcinoma | JAZF1 | 0.04 | 0.02 | blup | 224 | 0.03 | 3.8e-06 | 3.8 | 5.4 | 7.3e-08 | 0.49 | 0.57 | 0.27 | TRUE |
| 3 | The Cancer Genome Atlas | Thyroid Carcinoma | JAZF1 | 0.12 | 0.09 | lasso | 4 | 0.09 | 2.1e-09 | 6.5 | 6.8 | 1.2e-11 | 0.84 | 0.02 | 0.98 | TRUE |