TWAS
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Usage
Models
Genes
Traits
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Traits
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Impedance of arm (left)
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chr7:43,282,331-44,683,889
Best TWAS P=1.86e-08 · Best GWAS P=4.65e-06 conditioned to 0.0495
43.2M
43.4M
43.6M
43.8M
44M
44.2M
44.4M
44.6M
0
1
2
3
4
5
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
2
The Cancer Genome Atlas
Breast Invasive Carcinoma
POLR2J4
0.01
0.00
blup
49
0.01
5.9e-03
-4.3
5.6
1.9e-08
0.51
0.01
0.26
TRUE
1
GTEx
Lung
POLR2J4
0.10
0.02
enet
10
0.05
8.1e-05
4.5
5.2
1.9e-07
0.85
0.03
0.87
FALSE