Best TWAS P=1.86e-08 · Best GWAS P=4.65e-06 conditioned to 0.0495
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Lung | POLR2J4 | 0.10 | 0.02 | enet | 10 | 0.05 | 8.1e-05 | 4.5 | 5.2 | 1.9e-07 | 0.85 | 0.03 | 0.87 | FALSE |
| 2 | The Cancer Genome Atlas | Breast Invasive Carcinoma | POLR2J4 | 0.01 | 0.00 | blup | 49 | 0.01 | 5.9e-03 | -4.3 | 5.6 | 1.9e-08 | 0.51 | 0.01 | 0.26 | TRUE |