[Hub]/) : Traits : Impedance of arm (left) : ← →

chr7:71,652,312-75,842,792

Best TWAS P=3.04e-20 · Best GWAS P=5.8e-20 conditioned to 1

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
50	GTEx	Skin Sun Exposed Lower leg	MLXIPL	0.12	0.09	lasso	4	0.06	6.1e-06	-9.14	-9.2	3.0e-20	0.98	0.00	1.00	TRUE
6	GTEx	Adipose Visceral Omentum	MLXIPL	0.16	0.02	lasso	3	0.03	7.8e-03	-8.71	-8.8	1.7e-18	0.95	0.09	0.90	TRUE
67	METSIM	Adipose	BCL7B	0.10	0.02	enet	20	0.05	1.2e-07	-8.71	-7.6	4.0e-14	0.72	0.01	0.99	TRUE
33	GTEx	Esophagus Muscularis	MLXIPL	0.06	0.03	enet	10	0.03	1.1e-02	-4.03	-6.9	6.6e-12	0.57	0.10	0.68	TRUE
37	GTEx	Heart Left Ventricle	MLXIPL	0.14	0.00	enet	24	0.01	1.3e-01	-4.03	-6.6	3.1e-11	0.60	0.10	0.50	TRUE
82	The Cancer Genome Atlas	Thyroid Carcinoma	BCL7B	0.05	0.01	blup	5	0.03	1.3e-03	-7.67	6.5	6.3e-11	-0.46	0.00	0.63	TRUE
2	CommonMind	Brain Pre-frontal Cortex	STAG3L1	0.23	0.14	enet	13	0.17	1.0e-19	5.92	6.2	6.5e-10	-0.05	0.00	1.00	TRUE
69	METSIM	Adipose	POM121	0.05	0.03	blup	130	0.03	5.4e-06	-4.19	-6.2	6.9e-10	0.38	0.80	0.07	TRUE
74	ROSMAP	Brain Pre-frontal Cortex	PMS2P2	0.17	0.08	enet	8	0.08	6.0e-10	5.92	5.8	6.0e-09	-0.03	0.00	1.00	TRUE
75	ROSMAP	Brain Pre-frontal Cortex	FZD9	0.06	0.04	enet	3	0.04	7.1e-06	-4.19	-5.8	7.2e-09	0.39	0.59	0.19	TRUE
84	The Cancer Genome Atlas	Uterine Corpus Endometrial Carcinoma	PMS2L3	0.23	0.14	lasso	2	0.14	1.3e-04	5.92	5.7	1.1e-08	-0.01	0.00	0.91	TRUE
64	GTEx	Thyroid	POM121	0.06	0.01	enet	13	0.03	2.5e-03	-4.49	-5.7	1.3e-08	0.23	0.09	0.04	TRUE
36	GTEx	Esophagus Muscularis	STAG3L1	0.30	0.15	lasso	4	0.16	4.3e-10	5.92	5.6	1.8e-08	-0.03	0.00	1.00	TRUE
9	GTEx	Artery Aorta	STAG3L2	0.18	0.18	lasso	6	0.16	3.0e-09	-5.19	5.2	1.8e-07	0.01	0.00	1.00	TRUE
46	GTEx	Nerve Tibial	TRIM73	0.19	0.20	enet	6	0.20	6.3e-14	5.92	5.2	1.8e-07	-0.02	0.00	1.00	TRUE
34	GTEx	Esophagus Muscularis	PMS2P3	0.19	0.01	enet	42	0.06	2.1e-04	-0.73	5.2	2.6e-07	-0.02	0.03	0.38	TRUE
60	GTEx	Thyroid	MLXIPL	0.23	0.14	lasso	7	0.15	2.1e-11	-8.34	-9.2	4.6e-20	0.95	0.02	0.98	FALSE
47	GTEx	Skin Not Sun Exposed Suprapubic	MLXIPL	0.11	0.11	lasso	3	0.06	2.7e-04	-9.03	-9.1	1.1e-19	0.97	0.01	0.98	FALSE
22	GTEx	Cells Transformed fibroblasts	MLXIPL	0.13	0.06	enet	6	0.09	2.2e-07	-9.03	-9.0	3.5e-19	0.93	0.02	0.98	FALSE
3	GTEx	Adipose Subcutaneous	MLXIPL	0.11	0.07	enet	16	0.07	1.6e-06	-8.34	-8.9	4.6e-19	0.94	0.01	0.99	FALSE
68	METSIM	Adipose	MLXIPL	0.12	0.14	lasso	4	0.13	1.8e-19	-7.52	-8.6	1.2e-17	0.86	0.31	0.69	FALSE
7	GTEx	Adipose Visceral Omentum	NSUN5	0.07	0.03	enet	11	0.04	4.0e-03	-7.75	-8.0	1.5e-15	0.71	0.04	0.50	FALSE
80	The Cancer Genome Atlas	Lung Adenocarcinoma	MLXIPL	0.04	0.03	lasso	1	0.02	2.3e-03	-7.67	-7.7	1.7e-14	0.78	0.00	0.88	FALSE
53	GTEx	Spleen	NCF1B	0.22	0.10	enet	9	0.08	5.1e-03	-7.50	7.6	2.9e-14	-0.71	0.04	0.30	FALSE
78	The Cancer Genome Atlas	Breast Invasive Carcinoma	MLXIPL	0.06	0.05	lasso	2	0.05	5.1e-10	-7.67	-7.3	3.4e-13	0.77	0.00	1.00	FALSE
57	GTEx	Testis	MLXIPL	0.10	0.00	lasso	3	0.00	3.3e-01	-5.41	-7.2	4.9e-13	0.66	0.04	0.32	FALSE
39	GTEx	Lung	MLXIPL	0.10	0.07	enet	14	0.07	6.3e-06	-8.34	-6.3	2.6e-10	0.69	0.08	0.81	FALSE
81	The Cancer Genome Atlas	Prostate Adenocarcinoma	MLXIPL	0.08	0.05	enet	4	0.05	5.3e-06	-7.67	-6.0	1.8e-09	0.71	0.00	0.98	FALSE
1	CommonMind	Brain Pre-frontal Cortex	POM121C	0.08	0.05	lasso	2	0.04	1.1e-05	5.92	6.0	2.4e-09	-0.02	0.00	1.00	FALSE
51	GTEx	Skin Sun Exposed Lower leg	PMS2P3	0.38	0.30	lasso	3	0.29	1.9e-24	5.92	6.0	2.4e-09	-0.01	0.00	1.00	FALSE
59	GTEx	Testis	STAG3L1	0.24	0.24	enet	14	0.27	1.4e-12	5.92	6.0	2.5e-09	-0.04	0.00	1.00	FALSE
29	GTEx	Esophagus Mucosa	PMS2P3	0.14	0.15	lasso	2	0.14	9.7e-10	5.92	6.0	2.6e-09	-0.01	0.00	1.00	FALSE
42	GTEx	Muscle Skeletal	TRIM73	0.08	0.05	enet	11	0.06	3.4e-06	5.92	6.0	2.7e-09	0.00	0.00	1.00	FALSE
12	GTEx	Artery Tibial	POM121C	0.12	0.10	lasso	1	0.10	6.8e-08	5.92	5.9	3.3e-09	-0.02	0.00	1.00	FALSE
20	GTEx	Breast Mammary Tissue (Female)	STAG3L1	0.04	0.12	lasso	1	0.04	2.9e-02	5.92	5.9	3.3e-09	-0.02	0.00	0.96	FALSE
27	GTEx	Colon Transverse	STAG3L1	0.22	0.18	lasso	1	0.16	4.0e-08	5.92	5.9	3.3e-09	-0.02	0.00	1.00	FALSE
30	GTEx	Esophagus Mucosa	POM121C	0.13	0.10	lasso	1	0.07	1.0e-05	5.92	5.9	3.3e-09	-0.02	0.00	1.00	FALSE
32	GTEx	Esophagus Mucosa	STAG3L1	0.19	0.19	lasso	1	0.18	2.4e-12	5.92	5.9	3.3e-09	-0.02	0.00	1.00	FALSE
38	GTEx	Heart Left Ventricle	POM121C	0.13	0.12	lasso	1	0.09	2.2e-05	5.92	5.9	3.3e-09	-0.02	0.00	1.00	FALSE
49	GTEx	Skin Not Sun Exposed Suprapubic	STAG3L1	0.13	0.19	lasso	1	0.18	2.6e-10	5.92	5.9	3.3e-09	-0.02	0.00	1.00	FALSE
70	METSIM	Adipose	POM121C	0.11	0.08	lasso	1	0.08	1.6e-11	5.92	5.9	3.3e-09	-0.02	0.00	1.00	FALSE
72	ROSMAP	Brain Pre-frontal Cortex	PMS2P3	0.05	0.04	lasso	1	0.03	4.6e-05	5.92	5.9	3.3e-09	-0.02	0.00	1.00	FALSE
77	ROSMAP	Brain Pre-frontal Cortex	GTF2IP1	0.09	0.06	lasso	3	0.05	1.7e-07	5.92	5.9	3.3e-09	-0.02	0.06	0.94	FALSE
13	GTEx	Artery Tibial	STAG3L1	0.25	0.19	lasso	4	0.19	8.3e-15	5.92	5.9	3.4e-09	-0.01	0.00	1.00	FALSE
76	ROSMAP	Brain Pre-frontal Cortex	STAG3L1	0.46	0.32	lasso	4	0.32	2.2e-42	5.92	5.9	3.7e-09	-0.01	0.00	1.00	FALSE
8	GTEx	Adipose Visceral Omentum	STAG3L1	0.20	0.19	lasso	3	0.17	2.3e-09	5.92	5.9	3.9e-09	-0.02	0.00	1.00	FALSE
41	GTEx	Muscle Skeletal	PMS2P3	0.07	0.07	lasso	2	0.06	3.8e-06	5.92	5.9	3.9e-09	-0.01	0.00	1.00	FALSE
24	GTEx	Cells Transformed fibroblasts	POM121C	0.15	0.06	lasso	5	0.07	1.2e-05	5.92	5.9	4.1e-09	-0.01	0.00	1.00	FALSE
66	GTEx	Whole Blood	STAG3L1	0.08	0.06	lasso	3	0.07	2.8e-07	5.92	5.9	4.2e-09	-0.01	0.00	1.00	FALSE
58	GTEx	Testis	TRIM73	0.20	0.21	lasso	2	0.19	6.2e-09	5.92	5.9	4.3e-09	-0.01	0.00	1.00	FALSE
83	The Cancer Genome Atlas	Thyroid Carcinoma	POM121C	0.08	0.07	lasso	3	0.07	3.6e-07	5.92	5.9	4.5e-09	-0.01	0.00	1.00	FALSE
79	The Cancer Genome Atlas	Breast Invasive Carcinoma	POM121C	0.04	0.04	lasso	2	0.03	1.2e-07	5.92	5.8	5.0e-09	-0.01	0.00	1.00	FALSE
52	GTEx	Skin Sun Exposed Lower leg	STAG3L1	0.27	0.15	lasso	5	0.15	1.3e-12	5.92	5.8	5.1e-09	-0.01	0.00	1.00	FALSE
40	GTEx	Lung	POM121C	0.13	0.10	lasso	3	0.10	7.8e-08	5.92	5.8	5.2e-09	-0.02	0.00	1.00	FALSE
25	GTEx	Cells Transformed fibroblasts	STAG3L1	0.22	0.17	lasso	4	0.18	2.6e-13	5.92	5.8	5.6e-09	-0.01	0.00	1.00	FALSE
14	GTEx	Brain Cerebellar Hemisphere	POM121C	0.33	0.32	lasso	3	0.30	1.4e-08	5.92	5.8	5.9e-09	-0.02	0.00	1.00	FALSE
48	GTEx	Skin Not Sun Exposed Suprapubic	PMS2P3	0.26	0.19	lasso	3	0.17	1.3e-09	5.92	5.8	6.1e-09	-0.02	0.00	1.00	FALSE
73	ROSMAP	Brain Pre-frontal Cortex	POM121C	0.36	0.26	lasso	7	0.27	2.8e-34	5.92	5.8	6.8e-09	-0.01	0.00	1.00	FALSE
18	GTEx	Breast Mammary Tissue	STAG3L1	0.16	0.15	lasso	2	0.14	8.7e-08	5.92	5.8	7.3e-09	-0.02	0.00	1.00	FALSE
28	GTEx	Esophagus Gastroesophageal Junction	STAG3L1	0.36	0.16	lasso	5	0.16	1.7e-06	5.92	5.8	7.8e-09	-0.04	0.00	1.00	FALSE
10	GTEx	Artery Aorta	STAG3L1	0.18	0.03	lasso	4	0.08	3.9e-05	5.92	5.7	9.6e-09	-0.02	0.00	1.00	FALSE
26	GTEx	Colon Sigmoid	STAG3L1	0.30	0.18	lasso	4	0.18	8.5e-07	5.92	5.7	1.0e-08	-0.02	0.00	1.00	FALSE
4	GTEx	Adipose Subcutaneous	PMS2P3	0.15	0.12	lasso	3	0.10	9.8e-09	5.59	5.7	1.1e-08	-0.01	0.00	1.00	FALSE
21	GTEx	Cells EBV-transformed lymphocytes	STAG3L1	0.43	0.21	enet	21	0.23	3.8e-08	5.92	5.7	1.1e-08	0.02	0.00	1.00	FALSE
45	GTEx	Nerve Tibial	POM121C	0.22	0.14	lasso	5	0.14	6.9e-10	5.92	5.7	1.2e-08	-0.01	0.00	1.00	FALSE
61	GTEx	Thyroid	POM121C	0.14	0.08	lasso	3	0.07	3.4e-06	5.92	5.7	1.5e-08	-0.01	0.00	1.00	FALSE
5	GTEx	Adipose Subcutaneous	STAG3L1	0.30	0.24	enet	24	0.27	2.4e-22	5.92	5.7	1.6e-08	0.00	0.00	1.00	FALSE
54	GTEx	Stomach	PMS2P3	0.16	0.07	lasso	5	0.09	3.7e-05	5.41	5.6	1.6e-08	0.01	0.00	0.99	FALSE
19	GTEx	Breast Mammary Tissue (Female)	POM121C	0.17	-0.01	lasso	3	0.02	6.3e-02	5.92	5.6	1.7e-08	-0.05	0.01	0.59	FALSE
35	GTEx	Esophagus Muscularis	TRIM73	0.12	0.07	lasso	2	0.05	3.5e-04	5.59	5.6	2.6e-08	-0.02	0.00	0.99	FALSE
23	GTEx	Cells Transformed fibroblasts	PMS2P3	0.23	0.15	lasso	6	0.15	1.4e-11	5.59	5.5	3.4e-08	0.00	0.00	1.00	FALSE
11	GTEx	Artery Coronary	STAG3L1	0.28	0.13	lasso	4	0.17	1.8e-06	5.41	5.5	4.2e-08	0.02	0.00	0.99	FALSE
43	GTEx	Muscle Skeletal	STAG3L1	0.16	0.10	enet	24	0.10	3.7e-10	5.92	5.5	4.7e-08	-0.03	0.00	1.00	FALSE
56	GTEx	Stomach	STAG3L1	0.35	0.20	lasso	5	0.18	4.2e-09	5.41	5.5	4.9e-08	0.02	0.01	0.99	FALSE
55	GTEx	Stomach	TRIM73	0.23	0.09	lasso	5	0.09	3.2e-05	5.92	5.4	5.7e-08	0.00	0.00	0.99	FALSE
17	GTEx	Breast Mammary Tissue	PMS2P3	0.19	0.14	lasso	4	0.19	3.5e-10	5.59	5.4	5.8e-08	-0.01	0.00	1.00	FALSE
65	GTEx	Thyroid	STAG3L1	0.36	0.24	enet	17	0.27	8.0e-21	5.92	5.4	8.2e-08	-0.02	0.00	1.00	FALSE
44	GTEx	Nerve Tibial	PMS2P3	0.29	0.13	enet	4	0.18	1.1e-12	5.41	5.3	1.2e-07	-0.03	0.01	0.99	FALSE
71	METSIM	Adipose	TRIM73	0.11	0.11	lasso	5	0.12	8.6e-18	5.59	5.3	1.5e-07	-0.01	0.00	1.00	FALSE
62	GTEx	Thyroid	TRIM73	0.21	0.17	lasso	4	0.18	1.6e-13	5.92	5.2	1.6e-07	-0.02	0.00	1.00	FALSE
15	GTEx	Brain Cerebellum	POM121C	0.30	0.15	lasso	8	0.08	2.4e-03	5.92	5.2	2.1e-07	0.01	0.00	0.97	FALSE
63	GTEx	Thyroid	GTF2IRD2	0.08	0.07	lasso	1	0.04	2.4e-04	-5.19	-5.2	2.1e-07	-0.01	0.00	0.97	FALSE
16	GTEx	Brain Putamen basal ganglia	PMS2P3	0.37	0.13	lasso	6	0.18	6.0e-05	5.41	5.2	2.4e-07	-0.01	0.01	0.85	FALSE
31	GTEx	Esophagus Mucosa	STAG3L2	0.23	0.16	lasso	3	0.16	1.0e-10	-5.19	5.2	2.4e-07	0.00	0.00	1.00	FALSE