[Hub]/) : Traits : Leg fat percentage (right) : →

chr1:903,104-3,172,702

Best TWAS P=3.27e-10 · Best GWAS P=1.16e-08 conditioned to 0.0157

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous RP1-283E3.4 0.65 0.14 lasso 9 0.33 5.1e-28 -3.2 -5.4 5.1e-08 0.00 0.14 0.15 FALSE
2 GTEx Artery Aorta RP1-283E3.4 0.60 0.12 lasso 9 0.27 3.2e-15 -3.2 -5.2 1.8e-07 -0.01 0.09 0.10 FALSE
3 GTEx Artery Tibial RP1-283E3.4 0.66 0.09 lasso 6 0.38 4.9e-31 -3.2 -5.2 1.9e-07 0.01 0.15 0.12 FALSE
4 GTEx Cells Transformed fibroblasts RP1-283E3.4 0.59 0.13 lasso 8 0.29 3.0e-22 2.5 -5.4 7.1e-08 0.01 0.16 0.02 FALSE
5 GTEx Esophagus Mucosa RP1-283E3.4 0.53 0.12 enet 20 0.22 4.1e-15 -3.2 -5.8 6.2e-09 0.02 0.14 0.15 FALSE
6 GTEx Esophagus Muscularis RP1-283E3.4 0.46 0.14 enet 23 0.24 1.6e-14 -3.2 -6.3 3.3e-10 0.01 0.14 0.14 TRUE
7 GTEx Esophagus Muscularis RP3-395M20.12 0.08 0.06 enet 6 0.06 2.3e-04 3.4 -5.3 1.2e-07 0.78 0.01 0.98 TRUE
8 GTEx Muscle Skeletal SLC35E2B 0.35 0.06 lasso 4 0.19 3.2e-18 -3.3 5.5 2.9e-08 0.01 0.14 0.15 FALSE
9 GTEx Muscle Skeletal RP1-283E3.4 0.51 0.12 lasso 6 0.29 2.4e-28 -3.2 -5.3 1.5e-07 0.01 0.14 0.15 FALSE
10 GTEx Muscle Skeletal RP11-345P4.10 0.54 0.06 lasso 7 0.29 4.7e-29 -3.3 5.3 1.4e-07 0.00 0.15 0.12 FALSE
11 GTEx Skin Not Sun Exposed Suprapubic RP1-283E3.4 0.48 0.12 lasso 5 0.31 1.1e-17 -3.2 -5.7 1.5e-08 0.01 0.08 0.08 FALSE
12 GTEx Thyroid RP1-283E3.4 0.59 0.04 lasso 10 0.22 3.8e-17 -3.2 -6.0 2.4e-09 0.00 0.11 0.11 FALSE