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chr1:5,611,729-7,460,433

Best TWAS P=2.22e-13 · Best GWAS P=1.62e-14 conditioned to 1

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
12	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	THAP3	0.05	0.04	blup	51	0.05	4.4e-06	-6.9	7.3	2.2e-13	-0.96	0.01	0.99	TRUE
8	GTEx	Testis	THAP3	0.22	0.19	lasso	5	0.22	3.1e-10	5.3	6.6	3.7e-11	-0.72	0.31	0.69	FALSE
1	CommonMind	Brain Pre-frontal Cortex	DNAJC11	0.03	0.03	lasso	5	0.04	3.1e-05	5.3	6.5	7.5e-11	-0.78	0.03	0.96	FALSE
6	GTEx	Heart Left Ventricle	THAP3	0.12	0.07	lasso	7	0.09	1.9e-05	-5.9	6.4	1.3e-10	-0.91	0.06	0.93	FALSE
10	The Cancer Genome Atlas	Brain Lower Grade Glioma	DNAJC11	0.02	0.00	blup	74	0.01	9.1e-03	5.3	6.4	1.6e-10	-0.74	0.03	0.52	FALSE
11	The Cancer Genome Atlas	Liver Hepatocellular Carcinoma	THAP3	0.08	0.04	enet	7	0.04	3.7e-03	-7.2	6.1	1.3e-09	-0.89	0.02	0.88	FALSE
9	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	THAP3	0.06	0.02	blup	51	0.03	2.8e-04	-6.9	5.7	1.4e-08	-0.87	0.01	0.97	FALSE
2	CommonMind	Brain Pre-frontal Cortex	PLEKHG5	0.09	0.06	enet	28	0.05	3.1e-07	4.5	5.5	4.3e-08	-0.62	0.77	0.22	FALSE
4	GTEx	Breast Mammary Tissue	GPR153	0.13	0.03	lasso	5	0.01	1.3e-01	5.3	-5.4	7.3e-08	0.50	0.12	0.09	FALSE
3	CommonMind	Brain Pre-frontal Cortex	TNFRSF25	0.09	0.03	enet	22	0.06	1.1e-07	4.5	5.3	1.5e-07	-0.29	0.14	0.74	FALSE
7	GTEx	Muscle Skeletal	THAP3	0.14	0.10	lasso	8	0.14	2.4e-13	2.0	5.2	1.8e-07	-0.80	0.10	0.90	FALSE
5	GTEx	Breast Mammary Tissue (Female)	GPR153	0.07	-0.01	enet	3	0.00	4.3e-01	5.3	-5.2	1.9e-07	0.51	0.04	0.08	FALSE