[Hub]/) : Traits : Leg fat percentage (right) : ← →

chr1:5,611,729-7,460,433

Best TWAS P=2.22e-13 · Best GWAS P=1.62e-14 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex DNAJC11 0.03 0.03 lasso 5 0.04 3.1e-05 5.3 6.5 7.5e-11 -0.78 0.03 0.96 FALSE
2 CommonMind Brain Pre-frontal Cortex PLEKHG5 0.09 0.06 enet 28 0.05 3.1e-07 4.5 5.5 4.3e-08 -0.62 0.77 0.22 FALSE
3 CommonMind Brain Pre-frontal Cortex TNFRSF25 0.09 0.03 enet 22 0.06 1.1e-07 4.5 5.3 1.5e-07 -0.29 0.14 0.74 FALSE
4 GTEx Breast Mammary Tissue GPR153 0.13 0.03 lasso 5 0.01 1.3e-01 5.3 -5.4 7.3e-08 0.50 0.12 0.09 FALSE
5 GTEx Breast Mammary Tissue (Female) GPR153 0.07 -0.01 enet 3 0.00 4.3e-01 5.3 -5.2 1.9e-07 0.51 0.04 0.08 FALSE
6 GTEx Heart Left Ventricle THAP3 0.12 0.07 lasso 7 0.09 1.9e-05 -5.9 6.4 1.3e-10 -0.91 0.06 0.93 FALSE
7 GTEx Muscle Skeletal THAP3 0.14 0.10 lasso 8 0.14 2.4e-13 2.0 5.2 1.8e-07 -0.80 0.10 0.90 FALSE
8 GTEx Testis THAP3 0.22 0.19 lasso 5 0.22 3.1e-10 5.3 6.6 3.7e-11 -0.72 0.31 0.69 FALSE
9 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma THAP3 0.06 0.02 blup 51 0.03 2.8e-04 -6.9 5.7 1.4e-08 -0.87 0.01 0.97 FALSE
10 The Cancer Genome Atlas Brain Lower Grade Glioma DNAJC11 0.02 0.00 blup 74 0.01 9.1e-03 5.3 6.4 1.6e-10 -0.74 0.03 0.52 FALSE
11 The Cancer Genome Atlas Liver Hepatocellular Carcinoma THAP3 0.08 0.04 enet 7 0.04 3.7e-03 -7.2 6.1 1.3e-09 -0.89 0.02 0.88 FALSE
12 The Cancer Genome Atlas Lung Squamous Cell Carcinoma THAP3 0.05 0.04 blup 51 0.05 4.4e-06 -6.9 7.3 2.2e-13 -0.96 0.01 0.99 TRUE