TWAS
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Traits
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Traits
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Leg fat percentage (right)
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chr13:111,270,363-112,552,523
Best TWAS P=1.77e-09 · Best GWAS P=1.07e-16 conditioned to 1.79e-16
111.2M
111.4M
111.6M
111.8M
112M
112.2M
112.4M
112.6M
0
5
10
15
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
GTEx
Brain Frontal Cortex BA9
TEX29
0.45
0.10
lasso
8
0.24
4.2e-07
-4.8
-6.0
1.8e-09
-0.01
0.12
0.05
TRUE
2
The Cancer Genome Atlas
Brain Lower Grade Glioma
ARHGEF7
0.09
0.07
blup
142
0.08
3.1e-09
-4.3
5.7
9.5e-09
-0.04
1.00
0.00
FALSE