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chr17:41,555,474-42,998,534

Best TWAS P=4.95e-11 · Best GWAS P=1.42e-10 conditioned to 0.334

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	C17orf65	0.07	0.06	enet	15	0.07	4.5e-09	5.6	-5.3	9.0e-08	-0.84	0.46	0.53	FALSE
2	GTEx	Adipose Subcutaneous	ASB16-AS1	0.12	0.05	enet	16	0.05	3.7e-05	5.6	-5.2	2.5e-07	-0.75	0.16	0.60	FALSE
3	GTEx	Adipose Visceral Omentum	ASB16-AS1	0.14	0.12	lasso	5	0.10	9.8e-06	5.3	-5.4	5.3e-08	-0.84	0.17	0.81	FALSE
4	GTEx	Breast Mammary Tissue (Female)	ASB16-AS1	0.08	0.04	lasso	2	0.06	7.9e-03	5.3	-5.4	5.3e-08	-0.85	0.06	0.42	FALSE
5	GTEx	Cells Transformed fibroblasts	ASB16	0.14	0.14	lasso	3	0.12	2.0e-09	5.6	-5.6	1.7e-08	-0.89	0.34	0.66	FALSE
6	GTEx	Cells Transformed fibroblasts	ASB16-AS1	0.17	0.17	lasso	4	0.16	2.3e-12	5.6	-5.4	5.6e-08	-0.83	0.38	0.62	FALSE
7	GTEx	Esophagus Mucosa	ASB16	0.10	0.10	lasso	4	0.08	8.2e-06	5.6	-5.6	1.8e-08	-0.89	0.19	0.79	FALSE
8	GTEx	Esophagus Mucosa	ASB16-AS1	0.11	0.08	enet	16	0.07	3.7e-05	3.7	-5.1	2.9e-07	-0.78	0.41	0.56	FALSE
9	GTEx	Heart Left Ventricle	RP5-882C2.2	0.14	0.08	lasso	5	0.10	8.1e-06	6.0	-6.0	2.0e-09	-0.83	0.06	0.92	FALSE
10	GTEx	Nerve Tibial	ASB16	0.12	0.07	lasso	5	0.07	7.5e-06	5.6	-5.6	2.5e-08	-0.87	0.24	0.76	FALSE
11	GTEx	Nerve Tibial	ASB16-AS1	0.17	0.15	lasso	5	0.16	1.4e-11	5.6	-5.6	2.2e-08	-0.85	0.41	0.59	FALSE
12	GTEx	Skin Sun Exposed Lower leg	ASB16-AS1	0.13	0.09	lasso	5	0.07	2.7e-06	5.3	-5.3	1.1e-07	-0.87	0.48	0.52	FALSE
13	GTEx	Testis	ASB16-AS1	0.35	0.25	lasso	5	0.23	1.0e-10	5.6	-5.9	4.6e-09	-0.90	0.21	0.79	FALSE
14	GTEx	Thyroid	RP5-882C2.2	0.10	0.07	lasso	3	0.07	2.9e-06	5.6	-5.8	5.0e-09	-0.85	0.05	0.93	FALSE
15	GTEx	Thyroid	ASB16-AS1	0.14	0.06	lasso	2	0.04	5.4e-04	5.6	-5.7	1.5e-08	-0.89	0.20	0.66	FALSE
16	GTEx	Whole Blood	ASB16	0.11	0.03	enet	24	0.03	6.3e-04	5.3	-5.3	1.4e-07	-0.63	0.17	0.40	FALSE
17	GTEx	Whole Blood	ASB16-AS1	0.14	0.05	lasso	6	0.04	3.1e-04	5.6	-5.8	5.0e-09	-0.90	0.27	0.73	FALSE
18	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	C17orf65	0.03	0.00	blup	37	0.01	2.3e-02	5.6	-6.6	4.9e-11	-0.92	0.02	0.82	TRUE
19	The Cancer Genome Atlas	Colon Adenocarcinoma	ASB16	0.05	0.06	blup	40	0.05	4.6e-04	5.5	-5.7	1.5e-08	-0.90	0.08	0.76	FALSE
20	The Cancer Genome Atlas	Colon Adenocarcinoma	C17orf65	0.05	0.06	blup	38	0.05	4.2e-04	4.0	-5.8	6.0e-09	-0.90	0.16	0.63	FALSE
21	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	ASB16	0.02	0.02	blup	39	0.02	3.8e-03	6.4	-6.4	1.6e-10	-0.90	0.01	0.56	FALSE
22	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	C17orf65	0.03	0.01	lasso	10	0.02	3.6e-03	6.4	-6.2	4.8e-10	-0.82	0.02	0.92	FALSE
23	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	ASB16	0.02	0.03	blup	40	0.03	1.3e-04	5.3	-6.0	2.4e-09	-0.89	0.25	0.71	FALSE
24	The Cancer Genome Atlas	Brain Lower Grade Glioma	ASB16	0.03	0.03	lasso	3	0.03	3.2e-04	5.4	-5.4	6.7e-08	-0.85	0.22	0.59	FALSE
25	The Cancer Genome Atlas	Brain Lower Grade Glioma	C17orf65	0.04	0.04	blup	37	0.03	1.4e-04	5.6	-5.5	3.7e-08	-0.86	0.32	0.62	FALSE
26	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	ASB16	0.04	0.04	lasso	4	0.03	1.8e-04	6.4	-6.3	3.4e-10	-0.99	0.02	0.96	FALSE
27	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	C17orf65	0.07	0.05	lasso	6	0.05	3.1e-06	5.6	-5.4	5.6e-08	-0.88	0.07	0.92	FALSE
28	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	C17orf65	0.04	0.03	blup	39	0.03	2.7e-03	6.4	-5.3	1.1e-07	-0.89	0.02	0.82	FALSE
29	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	C17orf65	0.09	0.09	enet	8	0.08	2.9e-04	5.4	-5.9	3.6e-09	-0.91	0.06	0.84	FALSE
30	The Cancer Genome Atlas	Testicular Germ Cell Tumors	C17orf65	0.07	0.02	blup	38	0.04	1.1e-02	5.4	-6.3	3.0e-10	-0.86	0.02	0.36	FALSE
31	The Cancer Genome Atlas	Thyroid Carcinoma	C17orf65	0.03	0.03	lasso	7	0.03	3.8e-04	5.6	-6.0	1.8e-09	-0.94	0.06	0.83	FALSE