[Hub]/) : Traits : Leg fat percentage (right) :

chr17:45,271,680-47,718,188

Best TWAS P=1.03e-11 · Best GWAS P=1.05e-11 conditioned to 0.000315

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex SNF8 0.08 0.07 lasso 5 0.08 9.3e-10 -4.2 5.4 8.4e-08 -0.74 0.42 0.58 TRUE
2 GTEx Brain Caudate basal ganglia RP11-6N17.9 0.45 -0.01 enet 28 0.16 3.3e-05 -1.0 -5.7 1.2e-08 0.06 0.06 0.13 FALSE
3 GTEx Brain Cerebellar Hemisphere CDK5RAP3 0.22 0.10 lasso 6 0.09 2.6e-03 4.3 -5.2 2.2e-07 0.09 0.08 0.40 FALSE
4 GTEx Esophagus Muscularis COPZ2 0.14 0.04 lasso 5 0.06 1.3e-04 3.3 5.6 2.2e-08 -0.04 0.18 0.04 FALSE
5 GTEx Heart Left Ventricle ATP5G1 0.24 0.22 lasso 4 0.22 9.3e-12 -4.7 5.2 2.3e-07 -0.57 1.00 0.00 FALSE
6 GTEx Muscle Skeletal AC003665.1 0.05 0.03 enet 8 0.03 1.4e-03 4.4 5.3 9.7e-08 -0.10 0.12 0.72 FALSE
7 GTEx Ovary ATP5G1 0.15 0.08 enet 13 0.09 2.8e-03 -3.8 5.3 1.4e-07 -0.62 0.05 0.78 FALSE
8 GTEx Pancreas CDK5RAP3 0.11 -0.01 lasso 4 0.02 5.1e-02 4.3 -5.4 7.2e-08 0.06 0.09 0.18 FALSE
9 GTEx Pancreas RP11-6N17.9 0.15 0.04 lasso 5 0.04 9.3e-03 -1.3 -5.2 2.6e-07 0.08 0.13 0.17 FALSE
10 GTEx Stomach RP11-6N17.9 0.13 0.02 lasso 6 0.04 8.0e-03 4.9 -5.8 6.6e-09 0.05 0.11 0.69 FALSE
11 GTEx Testis RP11-6N17.4 0.14 0.02 lasso 10 0.02 4.8e-02 5.3 5.2 1.7e-07 -0.06 0.17 0.67 FALSE
12 The Cancer Genome Atlas Prostate Adenocarcinoma CBX1 0.03 0.04 lasso 4 0.04 3.7e-05 5.4 -5.3 1.2e-07 0.07 0.01 0.99 FALSE
13 The Cancer Genome Atlas Prostate Adenocarcinoma CDK5RAP3 0.06 0.00 blup 62 0.03 1.0e-03 -4.8 -6.8 1.0e-11 0.06 0.01 0.58 TRUE