Best TWAS P=7.93e-08 · Best GWAS P=5.27e-08 conditioned to 0.104
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Esophagus Muscularis | AC015971.2 | 0.09 | 0.03 | lasso | 6 | 0.05 | 0.00091 | 5.4 | -5.1 | 3.0e-07 | -0.89 | 0.02 | 0.94 | FALSE |
| 2 | The Cancer Genome Atlas | Liver Hepatocellular Carcinoma | RNF103 | 0.06 | 0.02 | blup | 42 | 0.02 | 0.02420 | -4.3 | 5.4 | 7.9e-08 | 0.86 | 0.02 | 0.43 | TRUE |