[Hub]/) : Traits : Leg fat percentage (right) : ← →

chr1:7,715,776-9,571,422

Best TWAS P=6.74e-12 · Best GWAS P=2.19e-11 conditioned to 1

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
21	YFS	Blood	RERE	0.09	0.15	lasso	4	0.16	5.7e-49	-6.7	6.9	6.7e-12	-0.98	0.00	1.00	TRUE
16	GTEx	Thyroid	RP5-1115A15.1	0.09	0.12	lasso	2	0.09	1.5e-07	-6.6	6.7	1.6e-11	-0.99	0.00	1.00	FALSE
8	GTEx	Esophagus Mucosa	RP5-1115A15.1	0.06	0.06	lasso	4	0.05	3.0e-04	-6.4	6.6	3.7e-11	-0.95	0.01	0.98	FALSE
10	GTEx	Lung	RP5-1115A15.1	0.05	0.08	lasso	1	0.07	1.0e-05	-6.6	6.6	3.7e-11	-1.00	0.00	1.00	FALSE
22	The Cancer Genome Atlas	Breast Invasive Carcinoma	RERE	0.02	0.03	lasso	2	0.03	4.7e-07	-6.7	6.6	4.3e-11	-0.98	0.00	1.00	FALSE
23	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	RERE	0.22	0.04	lasso	10	0.08	4.1e-04	-6.4	6.6	4.7e-11	-0.90	0.01	0.97	FALSE
17	GTEx	Whole Blood	RERE	0.19	0.15	lasso	4	0.13	2.7e-12	-6.4	6.5	8.2e-11	-0.98	0.01	0.99	FALSE
7	GTEx	Esophagus Mucosa	RERE	0.13	0.16	lasso	3	0.16	7.2e-11	-6.4	6.4	1.5e-10	-0.98	0.00	1.00	FALSE
9	GTEx	Lung	RERE	0.07	0.05	lasso	4	0.05	2.0e-04	-6.2	6.3	3.0e-10	-0.87	0.03	0.96	FALSE
13	GTEx	Skin Not Sun Exposed Suprapubic	RP5-1115A15.1	0.08	0.04	enet	8	0.04	3.0e-03	-6.1	6.3	3.4e-10	-0.95	0.02	0.96	FALSE
11	GTEx	Muscle Skeletal	RP5-1115A15.1	0.09	0.07	enet	10	0.06	1.5e-06	-6.4	6.1	8.1e-10	-0.87	0.00	1.00	FALSE
2	GTEx	Adipose Subcutaneous	RP5-1115A15.1	0.14	0.07	enet	20	0.10	2.6e-08	-6.6	6.1	9.2e-10	-0.88	0.00	1.00	FALSE
1	GTEx	Adipose Subcutaneous	RERE	0.20	0.23	lasso	2	0.24	1.7e-19	5.3	6.0	2.2e-09	-0.77	0.82	0.18	FALSE
3	GTEx	Adipose Visceral Omentum	RERE	0.22	0.17	lasso	5	0.17	5.2e-09	-6.4	6.0	2.3e-09	-0.90	0.01	0.99	FALSE
18	METSIM	Adipose	RERE	0.08	0.12	lasso	17	0.13	1.8e-19	5.2	6.0	2.3e-09	-0.80	0.65	0.35	FALSE
19	NTR	Blood	RERE	0.04	0.04	lasso	8	0.03	2.0e-11	-6.0	5.9	3.4e-09	-0.88	0.06	0.94	FALSE
20	ROSMAP	Brain Pre-frontal Cortex	RERE	0.15	0.15	lasso	7	0.15	1.5e-18	5.4	5.8	5.4e-09	-0.73	0.82	0.18	FALSE
15	GTEx	Skin Sun Exposed Lower leg	RP5-1115A15.1	0.07	0.03	enet	13	0.03	1.5e-03	-6.4	5.7	1.2e-08	-0.87	0.01	0.99	FALSE
6	GTEx	Cells Transformed fibroblasts	RERE	0.12	0.08	lasso	4	0.05	6.0e-05	5.5	5.6	2.5e-08	-0.67	0.31	0.68	FALSE
14	GTEx	Skin Sun Exposed Lower leg	RERE	0.14	0.05	lasso	8	0.08	4.3e-07	-6.4	5.4	6.3e-08	-0.90	0.01	0.99	FALSE
12	GTEx	Pancreas	RERE	0.11	0.12	lasso	4	0.07	5.9e-04	5.4	5.3	1.1e-07	-0.64	0.07	0.80	FALSE
5	GTEx	Breast Mammary Tissue	RP5-1115A15.1	0.10	0.07	lasso	2	0.03	7.0e-03	5.3	5.3	1.2e-07	-0.64	0.19	0.71	FALSE
4	GTEx	Breast Mammary Tissue	RERE	0.19	0.08	enet	10	0.14	8.0e-08	5.5	5.3	1.3e-07	-0.71	0.28	0.68	FALSE