Best TWAS P=8.21e-08 · Best GWAS P=9.35e-08 conditioned to 0.125
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Brain Cerebellum | TTC30A | 0.13 | 0.13 | lasso | 2 | 0.14 | 5.8e-05 | 5.1 | 5.2 | 2.5e-07 | 0.96 | 0.03 | 0.91 | FALSE |
| 2 | GTEx | Brain Nucleus accumbens basal ganglia | AC073834.3 | 0.16 | 0.01 | enet | 33 | 0.05 | 2.1e-02 | 4.8 | 5.2 | 2.6e-07 | 0.72 | 0.09 | 0.78 | FALSE |
| 3 | GTEx | Breast Mammary Tissue | AC073834.3 | 0.13 | 0.12 | lasso | 4 | 0.08 | 4.9e-05 | 4.6 | 5.2 | 2.4e-07 | 0.69 | 0.09 | 0.90 | FALSE |
| 4 | GTEx | Breast Mammary Tissue (Male) | AC073834.3 | 0.22 | 0.13 | enet | 18 | 0.07 | 8.7e-03 | 3.5 | 5.4 | 8.2e-08 | 0.84 | 0.06 | 0.81 | TRUE |
| 5 | GTEx | Esophagus Muscularis | AC073834.3 | 0.06 | 0.02 | lasso | 3 | 0.01 | 5.6e-02 | 5.1 | 5.2 | 2.2e-07 | 0.96 | 0.04 | 0.79 | FALSE |