TWAS
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Usage
Models
Genes
Traits
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Traits
:
Leg fat percentage (right)
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chr2:187,633,716-189,122,229
Best TWAS P=1.81e-07 · Best GWAS P=3.11e-08 conditioned to 0.0378
187.6M
187.8M
188M
188.2M
188.4M
188.6M
188.8M
189M
189.2M
0
2
4
6
8
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
GTEx
Cells Transformed fibroblasts
TFPI
0.07
0.04
lasso
4
0.03
1.6e-03
-5.0
-5.2
1.8e-07
0.85
0.10
0.84
TRUE
2
The Cancer Genome Atlas
Brain Lower Grade Glioma
CALCRL
0.03
0.04
blup
62
0.04
1.4e-05
-4.5
5.1
2.8e-07
-0.88
0.14
0.85
FALSE