Best TWAS P=1.81e-07 · Best GWAS P=3.11e-08 conditioned to 0.0378
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Cells Transformed fibroblasts | TFPI | 0.07 | 0.04 | lasso | 4 | 0.03 | 1.6e-03 | -5.0 | -5.2 | 1.8e-07 | 0.85 | 0.10 | 0.84 | TRUE |
| 2 | The Cancer Genome Atlas | Brain Lower Grade Glioma | CALCRL | 0.03 | 0.04 | blup | 62 | 0.04 | 1.4e-05 | -4.5 | 5.1 | 2.8e-07 | -0.88 | 0.14 | 0.85 | FALSE |