[Hub]/) : Traits : Leg fat percentage (right) :

chr4:69,713-1,610,872

Best TWAS P=6.7e-12 · Best GWAS P=1.3e-08 conditioned to 0.0268

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex SLC26A1 0.12 0.06 bslmm 400 0.08 8.0e-10 4.8 5.7 9.6e-09 0.51 0.15 0.84 TRUE
2 GTEx Adipose Subcutaneous RP11-440L14.1 0.58 0.38 enet 36 0.48 1.9e-43 -3.2 5.2 2.6e-07 0.16 0.94 0.01 FALSE
3 GTEx Artery Tibial GAK 0.19 0.03 enet 29 0.10 2.4e-08 -3.1 5.3 1.1e-07 0.59 0.01 0.99 FALSE
4 GTEx Brain Cerebellum SLC26A1 0.61 0.41 enet 22 0.46 2.1e-15 4.8 5.6 2.3e-08 0.57 0.12 0.87 FALSE
5 GTEx Cells Transformed fibroblasts SLC26A1 0.36 0.22 enet 24 0.26 1.4e-19 4.9 5.2 1.7e-07 0.62 0.15 0.84 FALSE
6 GTEx Nerve Tibial CPLX1 0.26 0.05 lasso 5 0.09 1.1e-06 -4.9 5.1 3.1e-07 0.16 0.16 0.83 FALSE
7 GTEx Pituitary SLC26A1 0.37 0.38 enet 14 0.33 3.9e-09 4.9 5.4 7.4e-08 0.65 0.10 0.88 FALSE
8 GTEx Stomach SLC26A1 0.26 0.17 enet 14 0.16 4.0e-08 4.8 6.2 6.2e-10 0.63 0.09 0.90 FALSE
9 NTR Blood PCGF3 0.07 0.00 enet 33 0.02 7.7e-08 4.7 5.5 4.2e-08 0.27 0.25 0.69 FALSE
10 The Cancer Genome Atlas Breast Invasive Carcinoma PCGF3 0.03 0.00 blup 69 0.01 3.7e-03 4.7 6.9 6.7e-12 0.34 0.01 0.56 TRUE
11 The Cancer Genome Atlas Brain Lower Grade Glioma PCGF3 0.08 0.02 lasso 4 0.07 1.9e-08 -4.0 5.3 1.1e-07 0.14 0.04 0.68 FALSE
12 The Cancer Genome Atlas Testicular Germ Cell Tumors PCGF3 0.13 0.00 blup 69 0.04 1.4e-02 -4.9 5.7 1.5e-08 0.10 0.01 0.59 FALSE