[Hub]/) : Traits : Leg fat percentage (right) : ← →

chr4:2,152,449-3,943,984

Best TWAS P=2.14e-09 · Best GWAS P=6.44e-08 conditioned to 0.435

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
2	GTEx	Cells Transformed fibroblasts	NOP14	0.12	0.06	enet	11	0.09	2.9e-07	-4.1	6.0	2.1e-09	-0.77	0.08	0.91	TRUE
11	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	C4orf44	0.03	0.02	blup	42	0.02	8.0e-04	-4.9	5.6	2.4e-08	-0.32	0.01	0.95	TRUE
10	The Cancer Genome Atlas	Cervical Squamous Cell Carcinoma	RNF4	0.14	0.02	blup	47	0.07	3.1e-04	4.3	5.2	1.8e-07	-0.22	0.00	0.12	TRUE
1	GTEx	Adrenal Gland	GRK4	0.38	0.25	lasso	5	0.29	5.1e-11	-4.7	5.7	1.3e-08	-0.88	0.10	0.89	FALSE
3	GTEx	Colon Transverse	GRK4	0.27	0.25	enet	18	0.25	2.4e-12	-4.9	5.6	2.0e-08	-0.95	0.02	0.97	FALSE
13	The Cancer Genome Atlas	Lung Adenocarcinoma	C4orf44	0.03	0.04	lasso	4	0.05	2.9e-06	-5.0	5.6	2.2e-08	-0.36	0.02	0.98	FALSE
8	GTEx	Whole Blood	HTT	0.10	0.00	enet	15	0.03	1.4e-03	5.1	5.5	3.9e-08	-0.40	0.07	0.56	FALSE
14	The Cancer Genome Atlas	Rectum Adenocarcinoma	GRK4	0.27	0.10	blup	76	0.13	7.3e-04	-4.7	5.4	8.6e-08	-0.87	0.04	0.76	FALSE
12	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	GRK4	0.09	0.18	lasso	5	0.20	1.5e-22	-5.4	5.3	1.4e-07	-0.95	0.01	0.99	FALSE
6	GTEx	Pituitary	GRK4	0.17	0.00	enet	6	-0.01	5.6e-01	-5.4	5.3	1.5e-07	-0.99	0.03	0.64	FALSE
15	The Cancer Genome Atlas	Soft Tissue Sarcoma	GRK4	0.08	0.07	blup	77	0.09	4.4e-06	-4.5	5.2	1.8e-07	-0.90	0.06	0.93	FALSE
7	GTEx	Stomach	GRK4	0.22	0.19	lasso	7	0.19	2.6e-09	-5.1	5.2	2.2e-07	-0.96	0.04	0.96	FALSE
9	The Cancer Genome Atlas	Cervical Squamous Cell Carcinoma	GRK4	0.09	0.12	blup	76	0.12	1.7e-06	-4.6	5.2	2.4e-07	-0.93	0.04	0.96	FALSE
16	The Cancer Genome Atlas	Uterine Corpus Endometrial Carcinoma	GRK4	0.11	0.12	lasso	1	0.10	8.4e-04	-5.2	5.2	2.4e-07	-0.98	0.01	0.90	FALSE
4	GTEx	Esophagus Gastroesophageal Junction	GRK4	0.37	0.23	lasso	9	0.22	2.2e-08	-5.0	5.1	2.7e-07	-0.96	0.03	0.97	FALSE
5	GTEx	Lung	ADD1	0.09	0.02	enet	6	0.01	3.5e-02	3.7	5.1	3.1e-07	-0.71	0.25	0.51	FALSE