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chr4:17,104,059-18,507,692

Best TWAS P=3.2e-12 · Best GWAS P=1.05e-13 conditioned to 0.000305

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
4	GTEx	Breast Mammary Tissue (Male)	DCAF16	0.24	0.03	enet	18	-0.01	4.4e-01	6.0	-7.0	3.2e-12	-0.69	0.04	0.56	TRUE
6	GTEx	Spleen	DCAF16	0.35	0.02	lasso	5	0.11	8.5e-04	-4.7	-6.8	7.8e-12	-0.66	0.08	0.29	FALSE
11	The Cancer Genome Atlas	Brain Lower Grade Glioma	DCAF16	0.09	0.02	lasso	3	0.04	5.2e-05	-4.7	-6.6	3.2e-11	-0.55	0.24	0.39	FALSE
13	The Cancer Genome Atlas	Prostate Adenocarcinoma	DCAF16	0.04	0.04	blup	31	0.04	2.2e-05	-4.7	-6.6	4.1e-11	-0.60	0.21	0.40	FALSE
1	GTEx	Artery Aorta	DCAF16	0.10	0.01	enet	6	0.02	4.7e-02	5.6	-6.5	7.5e-11	-0.69	0.16	0.32	FALSE
15	The Cancer Genome Atlas	Thyroid Carcinoma	DCAF16	0.07	0.04	blup	31	0.07	4.9e-07	-5.0	-6.5	1.1e-10	-0.55	0.44	0.33	FALSE
7	GTEx	Thyroid	DCAF16	0.11	0.02	lasso	5	0.03	2.3e-03	-4.7	-6.3	3.6e-10	-0.53	0.32	0.43	FALSE
14	The Cancer Genome Atlas	Prostate Adenocarcinoma	NCAPG	0.02	0.02	blup	34	0.02	3.4e-03	6.5	6.0	1.9e-09	0.86	0.01	0.86	FALSE
8	ROSMAP	Brain Pre-frontal Cortex	DCAF16	0.04	0.02	bslmm	379	0.01	3.9e-02	6.0	-5.8	6.0e-09	-0.79	0.03	0.90	FALSE
12	The Cancer Genome Atlas	Brain Lower Grade Glioma	NCAPG	0.02	0.03	lasso	1	0.02	9.0e-04	5.8	5.8	6.8e-09	0.75	0.03	0.53	FALSE
10	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	NCAPG	0.14	0.07	lasso	3	0.07	5.2e-08	6.0	5.8	6.9e-09	0.73	0.93	0.07	FALSE
3	GTEx	Breast Mammary Tissue	DCAF16	0.12	0.08	lasso	4	0.10	6.4e-06	-4.7	-5.5	3.3e-08	-0.45	0.20	0.51	FALSE
5	GTEx	Esophagus Mucosa	DCAF16	0.10	0.02	lasso	4	0.02	8.3e-03	-4.7	-5.4	6.1e-08	-0.32	0.16	0.27	FALSE
2	GTEx	Artery Tibial	DCAF16	0.16	0.16	lasso	5	0.13	1.5e-10	-4.7	-5.2	1.5e-07	-0.31	1.00	0.00	FALSE
9	The Cancer Genome Atlas	Colon Adenocarcinoma	NCAPG	0.08	0.04	blup	34	0.09	1.1e-05	5.8	5.2	1.9e-07	0.80	0.05	0.92	FALSE