Best TWAS P=7.4e-15 · Best GWAS P=7.88e-16 conditioned to 3.41e-07
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | ROSMAP | Brain Pre-frontal Cortex | LINC00461 | 0.10 | 0.07 | lasso | 2 | 0.05 | 4.5e-07 | 7.7 | 7.8 | 7.4e-15 | 0.95 | 0.00 | 1.00 | TRUE |
2 | ROSMAP | Brain Pre-frontal Cortex | CTC-498M16.2 | 0.11 | 0.13 | lasso | 6 | 0.12 | 1.2e-14 | -6.8 | -6.5 | 8.9e-11 | 0.13 | 0.93 | 0.07 | TRUE |