[Hub]/) : Traits : Leg fat percentage (right) :

chr8:21,249,296-22,666,279

Best TWAS P=2.27e-08 · Best GWAS P=1.86e-08 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Cells Transformed fibroblasts FAM160B2 0.18 0.09 lasso 5 0.10 4.0e-08 -5.6 5.4 6.8e-08 -0.98 0.00 1.00 FALSE
2 GTEx Cells Transformed fibroblasts AC091171.1 0.15 0.06 lasso 2 0.05 2.2e-04 -5.6 5.6 2.3e-08 -1.00 0.00 0.99 TRUE
3 GTEx Esophagus Mucosa NUDT18 0.21 0.23 enet 8 0.23 3.9e-15 -5.1 -5.1 2.8e-07 0.94 0.03 0.97 FALSE
4 GTEx Esophagus Mucosa AC091171.1 0.14 0.07 lasso 4 0.05 2.2e-04 5.0 5.2 2.2e-07 -0.71 0.02 0.97 FALSE
5 GTEx Skin Not Sun Exposed Suprapubic NUDT18 0.31 0.15 enet 13 0.22 4.6e-12 -5.1 -5.2 2.6e-07 0.90 0.03 0.96 FALSE
6 GTEx Testis NUDT18 0.42 0.40 lasso 4 0.41 1.3e-19 -5.1 -5.2 2.6e-07 0.95 0.03 0.97 FALSE
7 The Cancer Genome Atlas Cervical Squamous Cell Carcinoma NUDT18 0.09 0.03 blup 45 0.08 1.3e-04 -5.2 -5.5 3.0e-08 0.90 0.02 0.97 FALSE
8 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma NUDT18 0.10 0.16 lasso 2 0.16 2.3e-09 -5.2 -5.2 2.2e-07 0.96 0.01 0.99 FALSE
9 The Cancer Genome Atlas Brain Lower Grade Glioma FAM160B2 0.04 0.01 lasso 4 0.01 2.6e-02 -5.1 5.3 9.2e-08 -0.95 0.01 0.89 FALSE
10 The Cancer Genome Atlas Brain Lower Grade Glioma NUDT18 0.11 0.22 lasso 6 0.22 3.6e-24 -5.6 -5.5 2.9e-08 0.96 0.00 1.00 FALSE
11 The Cancer Genome Atlas Lung Squamous Cell Carcinoma NUDT18 0.06 0.08 lasso 3 0.07 1.6e-08 -5.2 -5.2 2.6e-07 0.96 0.01 0.99 FALSE
12 The Cancer Genome Atlas Prostate Adenocarcinoma FAM160B2 0.05 0.01 enet 11 0.03 1.7e-04 -5.5 5.2 1.8e-07 -0.80 0.01 0.98 FALSE
13 The Cancer Genome Atlas Prostate Adenocarcinoma NUDT18 0.17 0.25 blup 45 0.27 6.2e-28 -5.1 -5.3 1.1e-07 0.96 0.01 0.98 FALSE
14 The Cancer Genome Atlas Thyroid Carcinoma FAM160B2 0.08 0.06 lasso 4 0.05 1.4e-05 -5.6 5.5 4.7e-08 -0.93 0.00 1.00 FALSE
15 The Cancer Genome Atlas Uterine Corpus Endometrial Carcinoma NUDT18 0.15 0.17 lasso 4 0.12 2.3e-04 -5.5 -5.5 4.1e-08 0.94 0.01 0.98 FALSE