Best TWAS P=2.67e-07 · Best GWAS P=1.09e-06 conditioned to 1
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | CommonMind | Brain Pre-frontal Cortex | TRIM35 | 0.22 | 0.19 | lasso | 7 | 0.21 | 8.4e-25 | 4.9 | -5.2 | 2.7e-07 | -0.95 | 0 | 0.99 | TRUE |
2 | ROSMAP | Brain Pre-frontal Cortex | TRIM35 | 0.27 | 0.14 | bslmm | 620 | 0.18 | 5.0e-22 | 4.9 | -5.1 | 3.0e-07 | -0.85 | 0 | 0.99 | FALSE |